HitPredict

Interactor 1: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Interactor 2: EHMT1 (Q9H9B1)
Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D)
Gene: EHMT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12700765
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~SET
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 1298
+	Hs
		998821 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		EHMT1_HUMAN (12-1298): 0: 1070: 100.00
+	Hs
		1017218 H33_HUMAN (1-136): 1.86e-61: 186: 93.38		EHMT1_HUMAN (12-1298): 0: 1070: 100.00
+	Hs
		998691 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		EHMT2_HUMAN (149-1296): 0: 693: 47.60
+	Hs
		1162004 H31T_HUMAN (1-136): 1.34e-61: 187: 100.00		EHMT2_HUMAN (149-1296): 0: 693: 47.60
+	Hs
		1017122 H33_HUMAN (1-136): 1.86e-61: 186: 93.38		EHMT2_HUMAN (149-1296): 0: 693: 47.60
+	Hs
		1258917 H32_HUMAN (1-136): 6e-61: 185: 96.32		EHMT2_HUMAN (149-1296): 0: 693: 47.60
+	Hs
		998221 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		ANK2_HUMAN (181-1109): 6.84e-91: 327: 14.15
+	Hs
		1030664 H32_HUMAN (1-136): 6e-61: 185: 96.32		ANK2_HUMAN (181-1109): 6.84e-91: 327: 14.15
+	Hs
		216410 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		SUV91_HUMAN (949-1267): 7.41e-87: 290: 30.51
+	At
		947409 H33_ARATH (1-136): 6.71e-62: 187: 93.38		SUVH4_ARATH (978-1264): 1.4e-84: 291: 28.53
+	Hs
		216415 H33_HUMAN (1-136): 1.86e-61: 186: 93.38		SUV91_HUMAN (949-1267): 7.41e-87: 290: 30.51
+	Hs
		216473 H32_HUMAN (1-136): 6e-61: 185: 96.32		SUV91_HUMAN (949-1267): 7.41e-87: 290: 30.51
+	Hs
		998807 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		SUV92_HUMAN (1023-1267): 4.91e-84: 282: 36.36
+	Hs
		1017210 H33_HUMAN (1-136): 1.86e-61: 186: 93.38		SUV92_HUMAN (1023-1267): 4.91e-84: 282: 36.36
+	Sp
		237891 H31_SCHPO (1-136): 2.84e-59: 181: 88.97		CLR4_SCHPO (997-1265): 5.84e-81: 276: 34.12
+	Hs
		998263 H31_HUMAN (1-136): 3.36e-62: 188: 97.06		ANK3_HUMAN (712-1172): 3.26e-69: 259: 16.92
+	Mm
		1017384 H33_MOUSE (1-136): 1.86e-61: 186: 93.38		EHMT2_MOUSE (72-809): 1.68e-38: 159: 10.73
+	Dm
		121772 H3_DROME (1-136): 6e-61: 185: 96.32		M9PGH7_DROME (72-879): 3.35e-38: 158: 12.86
+	Dm
		381696 H3_DROME (1-136): 6e-61: 185: 96.32		SUV39_DROME (1022-1264): 3.43e-28: 124: 35.99
+	At
		947619 H31_ARATH (1-136): 1.56e-60: 184: 94.12		SUVR2_ARATH (1013-1264): 9.68e-28: 123: 30.97