HitPredict

Interactor 1: RRP4 (Q09704)
Exosome complex component rrp4 (Ribosomal RNA-processing protein 4)
Gene: RRP4

Interactor 2: RRP43 (Q10205)
Exosome complex component rrp43 (Ribosomal RNA-processing protein 43)
Gene: RRP43

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 30321377, 23503588
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ECR1_N~RNase_PH, ECR1_N~RNase_PH_C
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
and 10 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 329
Sp

1 270
+ Sp
+ Hs
+ Sc
+ Hs
+ Sp
+ Hs
+ Dm
+ At
+ At
+ Sp
+ Sc
+ At
+ Hs
+ Dm
+ Pf
+ At
+ Sc
+ At
+ Tb
+ Tb

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024