Protein: RCO1
Transcriptional regulatory protein RCO1

Gene: RCO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 100
UniProt ID: Q04779

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0006334 - nucleosome assembly
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

739914

RPD3
Histone deacetylase RPD3

12

20

Small-scale

0.980

High

650018

SIN3
Transcriptional regulatory protein SIN3

13

20

Small-scale

0.979

High

1048422

EAF3
Chromatin modification-related protein EAF3

9

13

Small-scale

0.971

High

963711

H3
Histone H3

5

20

Small-scale

0.906

High

1048412

RCO1
Transcriptional regulatory protein RCO1

3

18

Small-scale

0.817

High

381633

H2B2
Histone H2B.2

2

20

High-throughput

0.776

High

381258

H2B1
Histone H2B.1

2

20

High-throughput

0.737

High

419870

H2A2
Histone H2A.2

2

20

High-throughput

0.737

High

1040446

UME1
Transcriptional regulatory protein UME1

9

0

Small-scale

0.720

High

1042370

GCN5
Histone acetyltransferase GCN5

1

18

High-throughput

0.691

High

382338

H4
Histone H4

3

16

High-throughput

0.624

High

580051

HSC82
ATP-dependent molecular chaperone HSC82

4

6

High-throughput

0.619

High

741113

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

16

High-throughput

0.618

High

546238

SSB1
Ribosome-associated molecular chaperone SSB1

2

12

High-throughput

0.601

High

819767

SSB2
Ribosome-associated molecular chaperone SSB2

2

12

High-throughput

0.588

High

594565

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

3

Small-scale

0.584

High

743137

STH1
Nuclear protein STH1/NPS1

1

20

High-throughput

0.575

High

744342

CHD1
Chromo domain-containing protein 1

1

20

High-throughput

0.575

High

1048420

YRA1
RNA annealing protein YRA1

1

19

High-throughput

0.575

High

1048425

H2AZ
Histone H2A.Z

1

20

High-throughput

0.575

High

734475

BTAF1
TATA-binding protein-associated factor MOT1

2

20

Small-scale

0.571

High

527650

HSP72
Heat shock protein SSA2

2

12

High-throughput

0.552

High

808778

NAB3
Nuclear polyadenylated RNA-binding protein 3

1

0

High-throughput

0.546

High

893339

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

14

High-throughput

0.536

High

689657

RS7A
Small ribosomal subunit protein eS7A

2

3

High-throughput

0.526

High

781065

T2EA
Transcription initiation factor IIE subunit alpha

1

1

High-throughput

0.515

High

863949

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

20

High-throughput

0.515

High

1039036

IMA1
Importin subunit alpha

1

20

High-throughput

0.515

High

676676

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.513

High

393318

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.479

High

402113

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

9

Small-scale

0.479

High

647220

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

6

High-throughput

0.479

High

708152

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

745872

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

7

High-throughput

0.479

High

778529

RS27A
Small ribosomal subunit protein eS27A

1

6

High-throughput

0.479

High

925045

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.479

High

1044740

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

1048424

CMR1
DNA damage-binding protein CMR1

1

20

High-throughput

0.479

High

585371

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

4

High-throughput

0.470

High

738113

MYO4
Myosin-4

1

7

High-throughput

0.470

High

748040

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

764000

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

1048415

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

1048417

SGO1
Shugoshin

1

0

High-throughput

0.458

High

358334

ADH1
Alcohol dehydrogenase 1

1

2

High-throughput

0.445

High

459165

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

3

High-throughput

0.445

High

525116

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

531887

RL4A
Large ribosomal subunit protein uL4A

1

6

High-throughput

0.445

High

561531

TBP
TATA-box-binding protein

1

3

High-throughput

0.445

High

671112

SIS1
Protein SIS1

1

2

High-throughput

0.445

High

742375

HSP7F
Heat shock protein homolog SSE1

1

19

High-throughput

0.445

High

742943

HSP79
Heat shock protein homolog SSE2

1

19

High-throughput

0.445

High

793995

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

20

High-throughput

0.445

High

794221

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

20

High-throughput

0.445

High

804446

SSZ1
Ribosome-associated complex subunit SSZ1

1

9

High-throughput

0.445

High

811393

CAJ1
Protein CAJ1

1

7

High-throughput

0.445

High

823037

ATAD2
ATPase histone chaperone YTA7

1

4

High-throughput

0.445

High

850574

RSC8
Chromatin structure-remodeling complex protein RSC8

1

14

High-throughput

0.445

High

917405

ITC1
Imitation switch two complex protein 1

1

8

High-throughput

0.445

High

1010210

ARP4
Actin-related protein 4

1

10

High-throughput

0.445

High

1026829

CDC14
Tyrosine-protein phosphatase CDC14

1

8

High-throughput

0.445

High

1036343

ADA2
SAGA complex subunit ADA2

1

14

High-throughput

0.445

High

1048413

ARP9
Actin-like protein ARP9

1

10

High-throughput

0.445

High

1048414

IMB1
Importin subunit beta-1

1

13

High-throughput

0.445

High

1048419

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

20

High-throughput

0.445

High

1048423

CAF1A
Chromatin assembly factor 1 subunit A

1

6

High-throughput

0.445

High

843232

ZIM17
Mitochondrial protein import protein ZIM17

1

0

High-throughput

0.438

High

433845

RL26A
Large ribosomal subunit protein uL24A

1

6

High-throughput

0.437

High

442109

RS14A
Small ribosomal subunit protein uS11A

1

6

High-throughput

0.437

High

455258

RS19A
Small ribosomal subunit protein eS19A

1

6

High-throughput

0.437

High

503238

RS22A
Small ribosomal subunit protein uS8A

1

6

High-throughput

0.437

High

504412

RL31A
Large ribosomal subunit protein eL31A

1

7

High-throughput

0.437

High

512649

RS6A
Small ribosomal subunit protein eS6A

1

8

High-throughput

0.437

High

514835

RS18A
Small ribosomal subunit protein uS13A

1

4

High-throughput

0.437

High

674835

RS2
Small ribosomal subunit protein uS5

1

7

High-throughput

0.437

High

753585

RS3A1
Small ribosomal subunit protein eS1A

1

6

High-throughput

0.437

High

802385

RS20
Small ribosomal subunit protein uS10

1

5

High-throughput

0.437

High

874526

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.437

High

1033562

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.437

High

1048418

RS10A
Small ribosomal subunit protein eS10A

1

9

High-throughput

0.437

High

745614

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

0

High-throughput

0.426

High

921165

H1
Histone H1

1

0

High-throughput

0.426

High

1040998

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.426

High

1035082

UBC7
Ubiquitin-conjugating enzyme E2 7

1

17

High-throughput

0.417

High

1048426

VPS5
Vacuolar protein sorting-associated protein 5

1

3

High-throughput

0.417

High

453789

PYR1
Multifunctional protein URA2

1

7

High-throughput

0.407

High

510809

HSP77
Import motor subunit, mitochondrial

1

17

High-throughput

0.407

High

592496

VATB
V-type proton ATPase subunit B

1

10

High-throughput

0.407

High

639067

VPS1
Vacuolar protein sorting-associated protein 1

1

2

High-throughput

0.407

High

755174

GCN1
eIF-2-alpha kinase activator GCN1

1

10

High-throughput

0.407

High

811164

TCPZ
T-complex protein 1 subunit zeta

1

5

High-throughput

0.407

High

826486

DJP1
DnaJ-like protein 1

1

7

High-throughput

0.407

High

836890

MPG1
Mannose-1-phosphate guanyltransferase

1

3

High-throughput

0.407

High

1048416

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

6

High-throughput

0.407

High

752718

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

850382

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.232

Low

863729

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

864328

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low

1048421

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025