Protein: TSC1
Hamartin (Tuberous sclerosis 1 protein homolog)

Gene: TSC1
Organism: Mus musculus
Interactions: 123
UniProt ID: Q9EP53

Gene Ontology (top 5):
GO:0000054 - ribosomal subunit export from nucleus
GO:0001822 - kidney development
GO:0001843 - neural tube closure
GO:0002250 - adaptive immune response
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1112023

Q3TQ10
TSC complex subunit 2

5

13

Small-scale

0.702

High

1321952

TBCD7
TBC1 domain family member 7

2

2

Small-scale

0.611

High

906373

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

2

20

High-throughput

0.601

High

1142070

TSC2
Tuberin

2

13

Small-scale

0.571

High

69653

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

4

High-throughput

0.536

High

70574

PYR1
Multifunctional protein CAD

1

3

High-throughput

0.536

High

100088

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

11

High-throughput

0.536

High

432456

HS90A
Heat shock protein HSP 90-alpha

1

10

High-throughput

0.536

High

496131

IF4A2
Eukaryotic initiation factor 4A-II

1

9

High-throughput

0.536

High

513704

HS90B
Heat shock protein HSP 90-beta

1

10

High-throughput

0.536

High

515253

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

6

High-throughput

0.536

High

659469

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

6

High-throughput

0.536

High

660003

KIF5C
Kinesin heavy chain isoform 5C

1

6

High-throughput

0.536

High

699625

RASK
GTPase KRas

1

20

High-throughput

0.536

High

792285

TCPQ
T-complex protein 1 subunit theta

1

7

High-throughput

0.536

High

808375

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

6

High-throughput

0.536

High

829610

CDK5
Cyclin-dependent kinase 5

1

18

High-throughput

0.536

High

845410

RAB7A
Ras-related protein Rab-7a

1

20

High-throughput

0.536

High

885417

EF2
Elongation factor 2

1

6

High-throughput

0.536

High

898000

RAP2B
Ras-related protein Rap-2b

1

10

High-throughput

0.536

High

915338

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

14

High-throughput

0.536

High

919340

RAN
GTP-binding nuclear protein Ran

1

18

High-throughput

0.536

High

925818

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.536

High

926163

HSP7C
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.536

High

926300

DNJA1
DnaJ homolog subfamily A member 1

1

6

High-throughput

0.536

High

926881

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

930578

KPCG
Protein kinase C gamma type

1

13

High-throughput

0.536

High

930614

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

17

High-throughput

0.536

High

932638

RACK1
Small ribosomal subunit protein RACK1

1

15

High-throughput

0.536

High

933144

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

934637

KPCB
Protein kinase C beta type

1

12

High-throughput

0.536

High

936727

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

14

High-throughput

0.536

High

936741

TP53B
TP53-binding protein 1

1

10

High-throughput

0.536

High

946002

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.536

High

949410

TNIK
Traf2 and NCK-interacting protein kinase

1

20

High-throughput

0.536

High

964761

SC23A
Protein transport protein Sec23A

1

1

High-throughput

0.536

High

970164

CTNB1
Catenin beta-1

1

11

High-throughput

0.536

High

975151

EPHA4
Ephrin type-A receptor 4

1

8

High-throughput

0.536

High

990817

MPRI
Cation-independent mannose-6-phosphate receptor

1

1

High-throughput

0.536

High

1112520

WNK2
Serine/threonine-protein kinase WNK2

1

20

High-throughput

0.536

High

1116130

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

12

High-throughput

0.536

High

1131163

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

1

High-throughput

0.536

High

1141829

ARHG2
Rho guanine nucleotide exchange factor 2

1

11

High-throughput

0.536

High

1141983

FOXG1
Forkhead box protein G1

1

3

High-throughput

0.536

High

1142388

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

20

High-throughput

0.536

High

1142566

RASH
GTPase HRas

1

20

High-throughput

0.536

High

1142903

FXR1
RNA-binding protein FXR1

1

14

High-throughput

0.536

High

1143516

DLG4
Disks large homolog 4

1

6

High-throughput

0.536

High

1143844

TIF1B
Transcription intermediary factor 1-beta

1

13

High-throughput

0.536

High

1161349

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

7

High-throughput

0.536

High

1161541

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

6

High-throughput

0.536

High

1169788

KDM1A
Lysine-specific histone demethylase 1A

1

6

High-throughput

0.536

High

1186417

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

1

High-throughput

0.536

High

1193450

NISCH
Nischarin

1

14

High-throughput

0.536

High

1193490

CLAP1
CLIP-associating protein 1

1

6

High-throughput

0.536

High

1193537

SCRIB
Protein scribble homolog

1

4

High-throughput

0.536

High

1194466

WNK3
Serine/threonine-protein kinase WNK3

1

16

High-throughput

0.536

High

1195014

RHG32
Rho GTPase-activating protein 32

1

8

High-throughput

0.536

High

1207472

TENR
Tenascin-R

1

7

High-throughput

0.536

High

1207534

PAK5
Serine/threonine-protein kinase PAK 5

1

20

High-throughput

0.536

High

1208102

ABI1
Abl interactor 1

1

8

High-throughput

0.536

High

1208325

SMC2
Structural maintenance of chromosomes protein 2

1

6

High-throughput

0.536

High

1225194

MATR3
Matrin-3

1

8

High-throughput

0.536

High

1225231

DP13A
DCC-interacting protein 13-alpha

1

6

High-throughput

0.536

High

1247001

WASF1
Actin-binding protein WASF1

1

11

High-throughput

0.536

High

1257675

SFPQ
Splicing factor, proline- and glutamine-rich

1

14

High-throughput

0.536

High

1265042

RAB14
Ras-related protein Rab-14

1

14

High-throughput

0.536

High

1265874

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

10

High-throughput

0.536

High

1321687

LTOR1
Ragulator complex protein LAMTOR1

1

5

High-throughput

0.536

High

1322157

AMPD2
AMP deaminase 2

1

1

High-throughput

0.536

High

1322209

Q9ER67
MAGE family member D2

1

8

High-throughput

0.536

High

1322211

LGI1
Leucine-rich glioma-inactivated protein 1

1

1

High-throughput

0.536

High

1322212

CUL3
Cullin-3

1

16

High-throughput

0.536

High

1322213

MINK1
Misshapen-like kinase 1

1

20

High-throughput

0.536

High

1322214

DNJA4
DnaJ homolog subfamily A member 4

1

6

High-throughput

0.536

High

1322215

MAGD1
Melanoma-associated antigen D1

1

8

High-throughput

0.536

High

1322216

DNJA2
DnaJ homolog subfamily A member 2

1

6

High-throughput

0.536

High

1322218

TRIM3
Tripartite motif-containing protein 3

1

11

High-throughput

0.536

High

1322223

RASL1
RasGAP-activating-like protein 1

1

9

High-throughput

0.536

High

640194

EZRI
Ezrin

1

17

Small-scale

0.527

High

640210

RADI
Radixin

1

20

Small-scale

0.527

High

1322220

BEX3
Protein BEX3

1

3

Small-scale

0.515

High

292340

DCX
Neuronal migration protein doublecortin

1

0

High-throughput

0.513

High

659535

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.513

High

788771

PURA
Transcriptional activator protein Pur-alpha

1

0

High-throughput

0.513

High

1265093

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.513

High

88377

SHAN1
SH3 and multiple ankyrin repeat domains protein 1

1

14

High-throughput

0.500

High

874722

NCAN
Neurocan core protein

1

8

High-throughput

0.489

High

1157654

MTCL3
Microtubule cross-linking factor 3

1

20

High-throughput

0.489

High

1193578

SESD1
SEC14 domain and spectrin repeat-containing protein 1

1

20

High-throughput

0.489

High

1307803

TMED9
Transmembrane emp24 domain-containing protein 9

1

2

High-throughput

0.489

High

1321971

TMEDA
Transmembrane emp24 domain-containing protein 10

1

3

High-throughput

0.489

High

640201

MOES
Moesin

1

20

Small-scale

0.481

High

59969

A4FUW1
4932417H02Rik protein

1

20

High-throughput

0.479

High

103657

G5E8T2
RING-type E3 ubiquitin transferase

1

12

High-throughput

0.479

High

682126

AKT1
RAC-alpha serine/threonine-protein kinase

1

15

High-throughput

0.479

High

910338

1433E
14-3-3 protein epsilon

1

9

High-throughput

0.479

High

957155

DAB2
Disabled homolog 2

1

9

High-throughput

0.479

High

1111627

STING
Stimulator of interferon genes protein

1

6

High-throughput

0.479

High

1160025

Q6P5B5
FMR1 autosomal homolog 2

1

14

High-throughput

0.479

High

1206496

WDR48
WD repeat-containing protein 48

1

16

High-throughput

0.479

High

1206747

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

18

High-throughput

0.479

High

1207093

Q8BPK8
Agenet-like domain-containing protein

1

14

High-throughput

0.479

High

1208479

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

3

High-throughput

0.479

High

1322210

RBCC1
RB1-inducible coiled-coil protein 1

1

18

Small-scale

0.479

High

1322221

FOXO3
Forkhead box protein O3

1

9

High-throughput

0.479

High

291321

TTC3
E3 ubiquitin-protein ligase TTC3

1

11

High-throughput

0.445

High

729590

FMR1
Fragile X messenger ribonucleoprotein 1

1

14

High-throughput

0.445

High

1186645

ACTN1
Alpha-actinin-1

1

19

High-throughput

0.445

High

1225301

RPTOR
Regulatory-associated protein of mTOR

1

19

High-throughput

0.445

High

1321770

1433B
14-3-3 protein beta/alpha

1

20

Small-scale

0.445

High

1322217

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

2

High-throughput

0.445

High

1322219

TEN2
Teneurin-2

1

5

High-throughput

0.445

High

1322222

FXR2
RNA-binding protein FXR2

1

14

High-throughput

0.445

High

56994

A2A9M5
Dedicator of cytokinesis 7

1

5

High-throughput

0.437

High

82716

B9EJ72
Odz2 protein

1

4

High-throughput

0.437

High

1163329

RICTR
Rapamycin-insensitive companion of mTOR

1

5

Small-scale

0.437

High

1246798

DOCK7
Dedicator of cytokinesis protein 7

1

5

High-throughput

0.407

High

1129191

CNRP1
CB1 cannabinoid receptor-interacting protein 1

1

0

High-throughput

0.279

Low

1155799

FBX41
F-box only protein 41

1

0

High-throughput

0.279

Low

1206931

TCAF1
TRPM8 channel-associated factor 1

1

0

High-throughput

0.279

Low

1265721

CYRIB
CYFIP-related Rac1 interactor B

1

0

High-throughput

0.279

Low

46599

QSER1
Glutamine and serine-rich protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024