Protein: CDK3
Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)

Gene: CDK3
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q00526

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

758188

CDN1A
Cyclin-dependent kinase inhibitor 1

8

20

Small-scale

0.968

High

895413

CKS1
Cyclin-dependent kinases regulatory subunit 1

7

20

Small-scale

0.965

High

706796

CKS2
Cyclin-dependent kinases regulatory subunit 2

5

20

High-throughput

0.926

High

960080

CDK5
Cyclin-dependent kinase 5

4

17

High-throughput

0.909

High

590162

CCNA2
Cyclin-A2

4

20

High-throughput

0.903

High

624573

CCNE1
G1/S-specific cyclin-E1

4

20

High-throughput

0.903

High

625363

CDK2
Cyclin-dependent kinase 2

4

18

High-throughput

0.903

High

804104

CDN1B
Cyclin-dependent kinase inhibitor 1B

4

20

High-throughput

0.903

High

331637

CCNE2
G1/S-specific cyclin-E2

4

20

Small-scale

0.902

High

431741

HS90A
Heat shock protein HSP 90-alpha

4

18

High-throughput

0.895

High

438075

HS90B
Heat shock protein HSP 90-beta

4

18

High-throughput

0.895

High

624422

CCNC
Cyclin-C

4

20

Small-scale

0.894

High

414864

CDK1
Cyclin-dependent kinase 1

3

18

High-throughput

0.861

High

682166

AKT2
RAC-beta serine/threonine-protein kinase

3

8

High-throughput

0.861

High

836898

CDN1C
Cyclin-dependent kinase inhibitor 1C

3

20

High-throughput

0.861

High

960090

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

3

8

High-throughput

0.861

High

960108

SNIP1
Smad nuclear-interacting protein 1

2

1

High-throughput

0.811

High

538521

CCNB1
G2/mitotic-specific cyclin-B1

2

20

Small-scale

0.789

High

673140

CCND3
G1/S-specific cyclin-D3

2

20

High-throughput

0.783

High

851197

CCNH
Cyclin-H

2

20

High-throughput

0.783

High

960093

CCNI
Cyclin-I

2

20

High-throughput

0.783

High

960119

RGAP1
Rac GTPase-activating protein 1

2

3

High-throughput

0.783

High

960097

CDKN3
Cyclin-dependent kinase inhibitor 3

2

2

Small-scale

0.747

High

960099

H90B4
Putative heat shock protein HSP 90-beta 4

2

18

High-throughput

0.712

High

960100

HS905
Putative heat shock protein HSP 90-alpha A5

2

20

High-throughput

0.712

High

64006

SPDE4
Speedy protein E4

2

17

High-throughput

0.700

High

960089

SKP2
S-phase kinase-associated protein 2

4

6

High-throughput

0.699

High

585443

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

9

High-throughput

0.691

High

610205

CCNO
Cyclin-O

1

20

High-throughput

0.691

High

960087

STK4
Serine/threonine-protein kinase 4

1

11

High-throughput

0.691

High

960088

STK3
Serine/threonine-protein kinase 3

1

12

High-throughput

0.691

High

267144

GEMI
Geminin

3

2

High-throughput

0.667

High

960120

CDT1
DNA replication factor Cdt1

3

3

High-throughput

0.667

High

397911

ISG15
Ubiquitin-like protein ISG15

1

8

High-throughput

0.618

High

411675

LCK
Tyrosine-protein kinase Lck

1

12

High-throughput

0.618

High

435611

IGF1R
Insulin-like growth factor 1 receptor

1

15

High-throughput

0.618

High

622427

CCND1
G1/S-specific cyclin-D1

1

20

High-throughput

0.618

High

673388

MPIP1
M-phase inducer phosphatase 1

1

18

High-throughput

0.618

High

673468

MPIP2
M-phase inducer phosphatase 2

1

18

High-throughput

0.618

High

841543

RASF2
Ras association domain-containing protein 2

1

4

High-throughput

0.618

High

960095

CD5R1
Cyclin-dependent kinase 5 activator 1

1

7

Small-scale

0.618

High

960096

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

2

High-throughput

0.618

High

960098

LARP7
La-related protein 7

1

16

High-throughput

0.618

High

960103

RASF6
Ras association domain-containing protein 6

1

4

High-throughput

0.618

High

960106

RASF3
Ras association domain-containing protein 3

1

4

High-throughput

0.618

High

960110

RASF5
Ras association domain-containing protein 5

1

4

High-throughput

0.618

High

960117

CABL2
CDK5 and ABL1 enzyme substrate 2

1

8

Small-scale

0.618

High

960124

RASF1
Ras association domain-containing protein 1

1

6

High-throughput

0.618

High

178959

FOXP2
Forkhead box protein P2

2

5

High-throughput

0.606

High

641372

PAX6
Paired box protein Pax-6

2

6

High-throughput

0.606

High

686552

OTX2
Homeobox protein OTX2

2

8

High-throughput

0.606

High

960084

PAX8
Paired box protein Pax-8

2

5

High-throughput

0.606

High

960114

LHX4
LIM/homeobox protein Lhx4

2

2

High-throughput

0.606

High

960121

NELFA
Negative elongation factor A

2

3

High-throughput

0.606

High

960127

LHX3
LIM/homeobox protein Lhx3

2

3

High-throughput

0.606

High

414244

RB
Retinoblastoma-associated protein

2

10

Small-scale

0.602

High

960107

CCNQ
Cyclin-Q

1

20

Small-scale

0.590

High

275734

ZN189
Zinc finger protein 189

1

0

High-throughput

0.586

High

960126

ANFY1
Rabankyrin-5

1

0

High-throughput

0.586

High

909447

1433E
14-3-3 protein epsilon

2

5

High-throughput

0.584

High

960081

PAX5
Paired box protein Pax-5

2

7

High-throughput

0.553

High

960086

PPARA
Peroxisome proliferator-activated receptor alpha

1

9

High-throughput

0.541

High

503902

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.536

High

684635

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.536

High

685907

ARRB2
Beta-arrestin-2

1

1

High-throughput

0.536

High

928873

SKP1
S-phase kinase-associated protein 1

1

4

High-throughput

0.536

High

960083

EF1A2
Elongation factor 1-alpha 2

1

5

High-throughput

0.536

High

960091

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.536

High

960092

CUL1
Cullin-1

1

5

High-throughput

0.536

High

960104

CSN6
COP9 signalosome complex subunit 6

1

5

High-throughput

0.536

High

960112

CSN5
COP9 signalosome complex subunit 5

1

8

High-throughput

0.536

High

46684

A0A384NQ31
Epididymis secretory sperm binding protein

1

1

High-throughput

0.515

High

960102

Q6FHY5
MEOX2 protein

1

9

High-throughput

0.515

High

394544

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.501

High

960116

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

5

High-throughput

0.501

High

837929

MEOX2
Homeobox protein MOX-2

1

9

High-throughput

0.481

High

960109

FRS2
Fibroblast growth factor receptor substrate 2

1

1

High-throughput

0.481

High

960115

TRI63
E3 ubiquitin-protein ligase TRIM63

1

9

High-throughput

0.481

High

960118

TRI55
Tripartite motif-containing protein 55

1

13

High-throughput

0.481

High

303167

HEXI1
Protein HEXIM1

1

5

High-throughput

0.479

High

502908

MYH3
Myosin-3

1

12

High-throughput

0.479

High

522542

MYH1
Myosin-1

1

12

High-throughput

0.479

High

522604

MYH7
Myosin-7

1

12

High-throughput

0.479

High

528368

MYH6
Myosin-6

1

12

High-throughput

0.479

High

528405

MYH8
Myosin-8

1

12

High-throughput

0.479

High

646799

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

683268

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

683964

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

713942

HS71L
Heat shock 70 kDa protein 1-like

1

7

High-throughput

0.479

High

714185

HSP74
Heat shock 70 kDa protein 4

1

11

High-throughput

0.479

High

960082

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

960094

TFDP1
Transcription factor Dp-1

1

7

Small-scale

0.479

High

960122

SAV1
Protein salvador homolog 1

1

8

High-throughput

0.479

High

960128

MYH2
Myosin-2

1

12

High-throughput

0.479

High

960129

MYH13
Myosin-13

1

12

High-throughput

0.479

High

960130

MYH15
Myosin-15

1

12

High-throughput

0.479

High

960123

STN1
CST complex subunit STN1

1

0

High-throughput

0.460

High

960105

SHLD2
Shieldin complex subunit 2

1

0

High-throughput

0.458

High

371401

ANGI
Angiogenin

1

2

High-throughput

0.445

High

123567

PGRC1
Membrane-associated progesterone receptor component 1

1

4

Small-scale

0.437

High

801506

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

1

1

High-throughput

0.437

High

807687

MAP1B
Microtubule-associated protein 1B

1

4

High-throughput

0.437

High

960111

RIN2
Ras and Rab interactor 2

1

9

High-throughput

0.437

High

960113

KPBB
Phosphorylase b kinase regulatory subunit beta

1

1

High-throughput

0.437

High

960125

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

3

0

High-throughput

0.347

High

960101

OR2G6
Olfactory receptor 2G6

2

0

High-throughput

0.316

High

960085

NKG2E
NKG2-E type II integral membrane protein

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024