Protein: CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase)

Gene: CDKAL, CDKAL1
Organism: Homo sapiens
Interactions: 210
UniProt ID: Q5VV42

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005791 - rough endoplasmic reticulum
GO:0016020 - membrane
GO:0035598 - N6-threonylcarbomyladenosine methylthiotransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

282921

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

4

0

High-throughput

0.749

High

782251

NAA10
N-alpha-acetyltransferase 10

1

1

High-throughput

0.691

High

1015983

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

1

High-throughput

0.691

High

1138724

MMS19
MMS19 nucleotide excision repair protein homolog

5

0

Small-scale

0.682

High

1138676

TYW1B
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B

1

0

High-throughput

0.656

High

1138734

NAA50
N-alpha-acetyltransferase 50

1

1

High-throughput

0.618

High

1138709

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

4

High-throughput

0.611

High

1138762

CIA2B
Cytosolic iron-sulfur assembly component 2B

3

1

Small-scale

0.593

High

990489

CKAP4
Cytoskeleton-associated protein 4

2

0

High-throughput

0.585

High

1138764

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

2

0

High-throughput

0.585

High

360028

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

3

2

High-throughput

0.585

High

350241

RASK
GTPase KRas

2

4

High-throughput

0.584

High

507058

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.584

High

1138758

DYN3
Dynamin-3

2

2

High-throughput

0.574

High

178590

STX7
Syntaxin-7

2

1

High-throughput

0.558

High

513743

CP19A
Aromatase

1

1

High-throughput

0.536

High

885926

EVA1C
Protein eva-1 homolog C

1

1

High-throughput

0.536

High

897902

RAP1B
Ras-related protein Rap-1b

1

3

High-throughput

0.536

High

1044916

AVR2B
Activin receptor type-2B

1

1

High-throughput

0.536

High

1086121

AMHR2
Anti-Muellerian hormone type-2 receptor

1

1

High-throughput

0.536

High

1138689

LRRT1
Leucine-rich repeat transmembrane neuronal protein 1

1

1

High-throughput

0.536

High

1138696

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1138740

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.536

High

1138748

EVA1B
Protein eva-1 homolog B

1

1

High-throughput

0.536

High

591882

RAB4A
Ras-related protein Rab-4A

2

1

High-throughput

0.533

High

914126

RB11A
Ras-related protein Rab-11A

2

1

High-throughput

0.533

High

131577

STK25
Serine/threonine-protein kinase 25

1

0

High-throughput

0.513

High

199908

SPIT2
Kunitz-type protease inhibitor 2

1

0

High-throughput

0.513

High

240751

USO1
General vesicular transport factor p115

1

0

High-throughput

0.513

High

488255

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.513

High

794394

GRK6
G protein-coupled receptor kinase 6

1

0

High-throughput

0.513

High

1053766

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

1125013

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1138673

TM268
Transmembrane protein 268

1

0

High-throughput

0.513

High

1138691

ST32C
Serine/threonine-protein kinase 32C

1

0

High-throughput

0.513

High

1138700

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

1138707

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.513

High

1138710

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1138735

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

1138757

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

0

High-throughput

0.513

High

1138761

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.513

High

1138765

PCDB3
Protocadherin beta-3

1

0

High-throughput

0.513

High

383848

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

3

High-throughput

0.500

High

445852

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

3

High-throughput

0.500

High

1138731

TRI54
Tripartite motif-containing protein 54

1

3

High-throughput

0.494

High

1063444

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.493

High

281672

WFS1
Wolframin

1

0

High-throughput

0.493

High

130296

BT3A1
Butyrophilin subfamily 3 member A1

1

2

High-throughput

0.489

High

156841

FFAR1
Free fatty acid receptor 1

1

2

High-throughput

0.489

High

537747

INSRR
Insulin receptor-related protein

1

6

High-throughput

0.489

High

840726

DYN2
Dynamin-2

1

2

High-throughput

0.489

High

983384

DYN1
Dynamin-1

1

2

High-throughput

0.489

High

1067516

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.489

High

1138683

BT2A1
Butyrophilin subfamily 2 member A1

1

1

High-throughput

0.489

High

1138692

P2RY8
P2Y purinoceptor 8

1

1

High-throughput

0.489

High

48384

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.479

High

163842

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.479

High

167939

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

169181

MUSK
Muscle, skeletal receptor tyrosine-protein kinase

1

5

High-throughput

0.479

High

348717

RASN
GTPase NRas

1

4

High-throughput

0.479

High

435669

IGF1R
Insulin-like growth factor 1 receptor

1

6

High-throughput

0.479

High

436355

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

508057

FGFR1
Fibroblast growth factor receptor 1

1

2

High-throughput

0.479

High

527516

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

545433

RAC2
Ras-related C3 botulinum toxin substrate 2

1

6

High-throughput

0.479

High

567108

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

595264

LMNB1
Lamin-B1

1

2

High-throughput

0.479

High

651424

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

845532

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.479

High

892425

RAC3
Ras-related C3 botulinum toxin substrate 3

1

6

High-throughput

0.479

High

894121

CDC42
Cell division control protein 42 homolog

1

6

High-throughput

0.479

High

900573

RHOA
Transforming protein RhoA

1

7

High-throughput

0.479

High

951072

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.479

High

968403

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

4

High-throughput

0.479

High

1017667

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

1041772

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1053017

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.479

High

1087545

CAH9
Carbonic anhydrase 9

1

1

High-throughput

0.479

High

1132444

MARH8
E3 ubiquitin-protein ligase MARCHF8

1

1

High-throughput

0.479

High

1138674

RNF43
E3 ubiquitin-protein ligase RNF43

1

3

High-throughput

0.479

High

1138678

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.479

High

1138680

DJC14
DnaJ homolog subfamily C member 14

1

2

High-throughput

0.479

High

1138688

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

3

High-throughput

0.479

High

1138697

MIRO2
Mitochondrial Rho GTPase 2

1

10

High-throughput

0.479

High

1138702

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.479

High

1138705

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.479

High

1138706

RN139
E3 ubiquitin-protein ligase RNF139

1

2

High-throughput

0.479

High

1138712

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.479

High

1138720

DNJC1
DnaJ homolog subfamily C member 1

1

3

High-throughput

0.479

High

1138723

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

1138728

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

1138736

DJC25
DnaJ homolog subfamily C member 25

1

2

High-throughput

0.479

High

1138746

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.479

High

1138753

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1138754

SEC63
Translocation protein SEC63 homolog

1

1

High-throughput

0.479

High

1138760

DJC16
DnaJ homolog subfamily C member 16

1

1

High-throughput

0.479

High

118337

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

227725

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

273836

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

319228

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

390288

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

390952

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

514695

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.458

High

573742

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

648792

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

654424

CALX
Calnexin

1

0

High-throughput

0.458

High

785959

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

795158

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

813533

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

825441

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

838891

EMD
Emerin

1

0

High-throughput

0.458

High

847508

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

879809

TPTE
Putative tyrosine-protein phosphatase TPTE

1

0

High-throughput

0.458

High

890202

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

912953

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

917420

H4
Histone H4

1

0

High-throughput

0.458

High

961691

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.458

High

1040132

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1135068

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

1138679

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1138681

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1138684

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1138685

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1138686

NEK8
Serine/threonine-protein kinase Nek8

1

0

High-throughput

0.458

High

1138695

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1138701

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

1138703

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.458

High

1138715

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1138717

FAF2
FAS-associated factor 2

1

0

High-throughput

0.458

High

1138719

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1138721

TM237
Transmembrane protein 237

1

0

High-throughput

0.458

High

1138722

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1138726

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1138727

GORS1
Golgi reassembly-stacking protein 1

1

0

High-throughput

0.458

High

1138729

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1138732

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1138737

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

1138742

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1138744

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1138745

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

1138749

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

1138750

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1138752

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

1138756

CLC4E
C-type lectin domain family 4 member E

1

0

High-throughput

0.458

High

1138763

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

883533

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.445

High

120486

RHOD
Rho-related GTP-binding protein RhoD

1

7

High-throughput

0.437

High

164395

TRI66
Tripartite motif-containing protein 66

1

2

High-throughput

0.437

High

177914

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.437

High

591592

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.437

High

592307

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.437

High

665485

EPHA8
Ephrin type-A receptor 8

1

1

High-throughput

0.437

High

720670

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

844565

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.437

High

844986

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.437

High

852517

RND2
Rho-related GTP-binding protein RhoN

1

8

High-throughput

0.437

High

884510

RAB25
Ras-related protein Rab-25

1

1

High-throughput

0.437

High

940454

CXAR
Coxsackievirus and adenovirus receptor

1

1

High-throughput

0.437

High

1049063

TRI14
Tripartite motif-containing protein 14

1

2

High-throughput

0.437

High

1070241

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.437

High

1076616

RHOH
Rho-related GTP-binding protein RhoH

1

7

High-throughput

0.437

High

1081507

NTRK3
NT-3 growth factor receptor

1

5

High-throughput

0.437

High

1138677

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1138682

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1138687

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

1138699

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.437

High

1138718

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

1138738

Q9H4D1
Protein kinase

1

3

High-throughput

0.437

High

1138739

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1138751

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

1

High-throughput

0.437

High

1138755

ANC2
Anaphase-promoting complex subunit 2

1

2

High-throughput

0.437

High

1138759

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.437

High

529244

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

1103042

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.426

High

1138675

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

2

0

High-throughput

0.328

High

1138704

BPIB1
BPI fold-containing family B member 1

2

0

High-throughput

0.328

High

1138733

TTYH3
Protein tweety homolog 3

2

0

High-throughput

0.328

High

328869

TOP3B
DNA topoisomerase 3-beta-1

2

0

High-throughput

0.313

High

411760

LCK
Tyrosine-protein kinase Lck

1

0

High-throughput

0.299

High

63594

ASB14
Ankyrin repeat and SOCS box protein 14

1

0

High-throughput

0.279

Low

299170

CSCL1
CSC1-like protein 1

1

0

High-throughput

0.279

Low

307381

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.279

Low

625490

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.279

Low

959469

VIGLN
Vigilin

1

0

High-throughput

0.279

Low

1045048

CD166
CD166 antigen

1

0

High-throughput

0.279

Low

1138708

ITLN1
Intelectin-1

1

0

High-throughput

0.279

Low

1138713

T106A
Transmembrane protein 106A

1

0

High-throughput

0.279

Low

1138716

UPP
Uracil phosphoribosyltransferase homolog

1

0

High-throughput

0.279

Low

1138730

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.279

Low

1138743

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.279

Low

868216

ATX3
Ataxin-3

1

0

High-throughput

0.268

Low

174956

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.261

Low

205511

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

212868

STX6
Syntaxin-6

1

0

High-throughput

0.249

Low

402137

JUN
Transcription factor Jun

1

0

High-throughput

0.249

Low

546847

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.249

Low

670070

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.249

Low

779577

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

824097

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

881198

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.249

Low

1076978

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.249

Low

1138690

LBN
Limbin

1

0

High-throughput

0.249

Low

1138693

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1138694

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

1138698

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

1138711

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1138714

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

1138725

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low

1138741

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1138747

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024