Protein: IRGQ
Immunity-related GTPase family Q protein

Gene: IRGQ
Organism: Homo sapiens
Interactions: 26
UniProt ID: Q8WZA9

Gene Ontology (top 5):
GO:0005764 - lysosome
GO:0005776 - autophagosome
GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins
GO:0010508 - positive regulation of autophagy
GO:0030674 - protein-macromolecule adaptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1362110

MLP3B
Microtubule-associated protein 1 light chain 3 beta

3

3

High-throughput

0.653

High

1362113

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

2

3

High-throughput

0.606

High

963965

NPC2
NPC intracellular cholesterol transporter 2

2

0

High-throughput

0.602

High

952272

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

2

3

High-throughput

0.588

High

1362114

PLK2
Serine/threonine-protein kinase PLK2

1

3

High-throughput

0.536

High

242444

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.437

High

412343

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

606949

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.437

High

887450

CEBPD
CCAAT/enhancer-binding protein delta

1

1

Small-scale

0.437

High

530137

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

659691

NFYA
Nuclear transcription factor Y subunit alpha

3

0

High-throughput

0.347

High

248532

O10H3
Olfactory receptor 10H3

2

0

High-throughput

0.328

High

329875

OR5F1
Olfactory receptor 5F1

2

0

High-throughput

0.328

High

1307236

TF2LY
Homeobox protein TGIF2LY

2

0

High-throughput

0.328

High

1360289

SCG3
Secretogranin-3

2

0

High-throughput

0.328

High

1362111

S2532
Solute carrier family 25 member 32

2

0

High-throughput

0.328

High

106364

APRIO
Alternative prion protein

2

0

High-throughput

0.305

High

1161821

ZSC26
Zinc finger and SCAN domain-containing protein 26

1

0

High-throughput

0.279

Low

1259050

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

0

High-throughput

0.279

Low

260227

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

942782

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.249

Low

1254851

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1362112

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

0

Small-scale

0.249

Low

67081

S38A8
Solute carrier family 38 member 8

1

0

High-throughput

0.232

Low

404858

PRIO
Major prion protein

1

0

High-throughput

0.232

Low

1104033

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025