Protein: ESS2
Splicing factor ESS-2 homolog (DiGeorge syndrome critical region 13) (DiGeorge syndrome critical region 14) (DiGeorge syndrome protein H) (DGS-H) (Protein ES2)

Gene: ESS2
Organism: Homo sapiens
Interactions: 138
UniProt ID: Q96DF8

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0007399 - nervous system development
GO:0071013 - catalytic step 2 spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1174479

F10C1
Protein FRA10AC1

4

2

Small-scale

0.707

High

453883

RU2A
U2 small nuclear ribonucleoprotein A'

3

1

High-throughput

0.667

High

1197537

RALYL
RNA-binding Raly-like protein

3

3

High-throughput

0.667

High

1288177

PRP19
Pre-mRNA-processing factor 19

3

3

High-throughput

0.667

High

49691

F170A
Protein FAM170A

3

0

High-throughput

0.638

High

1245909

DNJB8
DnaJ homolog subfamily B member 8

3

0

High-throughput

0.638

High

1288174

IKZF3
Zinc finger protein Aiolos

3

0

High-throughput

0.638

High

504555

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.628

High

1288171

NXF1
Nuclear RNA export factor 1

3

0

High-throughput

0.625

High

912090

RUXG
Small nuclear ribonucleoprotein G

2

2

High-throughput

0.611

High

1288147

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

1

High-throughput

0.606

High

327804

SYF2
Pre-mRNA-splicing factor SYF2

2

0

High-throughput

0.602

High

556764

ACADS
Short-chain specific acyl-CoA dehydrogenase, mitochondrial

2

0

High-throughput

0.602

High

911712

RUXE
Small nuclear ribonucleoprotein E

2

0

High-throughput

0.602

High

927995

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

0

High-throughput

0.602

High

1288154

USB1
U6 snRNA phosphodiesterase 1

2

0

High-throughput

0.585

High

347549

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

360256

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

2

High-throughput

0.584

High

204408

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

1048714

DGCR6
Protein DGCR6

2

0

High-throughput

0.580

High

808219

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

1

High-throughput

0.571

High

387273

P53
Cellular tumor antigen p53

2

0

High-throughput

0.559

High

918598

H2B1C
Histone H2B type 1-C/E/F/G/I

2

0

High-throughput

0.559

High

1102779

CCD57
Coiled-coil domain-containing protein 57

2

1

High-throughput

0.553

High

443715

VIME
Vimentin

2

1

High-throughput

0.543

High

241346

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

3

High-throughput

0.536

High

432855

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

4

High-throughput

0.536

High

534262

YJU2B
Probable splicing factor YJU2B

1

1

High-throughput

0.536

High

639043

S100P
Protein S100-P

1

2

High-throughput

0.536

High

642979

S10A4
Protein S100-A4

1

2

High-throughput

0.536

High

871724

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.536

High

952071

SRSF3
Serine/arginine-rich splicing factor 3

1

1

High-throughput

0.536

High

1064587

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.536

High

278505

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.513

High

519058

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

586911

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

1029299

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

1039762

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

1092877

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

0

High-throughput

0.513

High

1204072

CARM1
Histone-arginine methyltransferase CARM1

1

0

High-throughput

0.513

High

1288158

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

1288163

HINT3
Adenosine 5'-monophosphoramidase HINT3

1

0

High-throughput

0.513

High

1288170

FOXJ2
Forkhead box protein J2

1

0

High-throughput

0.513

High

1288176

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

High-throughput

0.513

High

1288178

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

0

High-throughput

0.513

High

1288183

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.513

High

224826

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

2

High-throughput

0.508

High

929609

RACK1
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.508

High

1288156

RBM4
RNA-binding protein 4

1

2

High-throughput

0.508

High

808836

YAP1
Transcriptional coactivator YAP1

1

3

High-throughput

0.501

High

661385

S10A2
Protein S100-A2

1

2

High-throughput

0.489

High

1288164

DJC17
DnaJ homolog subfamily C member 17

1

1

High-throughput

0.489

High

1288169

HPBP1
Hsp70-binding protein 1

1

2

High-throughput

0.489

High

1063751

EXOS7
Exosome complex component RRP42

1

1

High-throughput

0.481

High

1288150

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

2

High-throughput

0.481

High

1288165

RBM22
Pre-mRNA-splicing factor RBM22

1

1

High-throughput

0.481

High

175103

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

379699

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

935098

H31
Histone H3.1

1

1

High-throughput

0.479

High

952536

H33
Histone H3.3

1

1

High-throughput

0.479

High

980834

TLE3
Transducin-like enhancer protein 3

1

2

High-throughput

0.479

High

1055446

DHX8
ATP-dependent RNA helicase DHX8

1

2

High-throughput

0.479

High

1254881

SP7
Transcription factor Sp7

1

1

High-throughput

0.479

High

1272072

CELF1
CUGBP Elav-like family member 1

1

1

High-throughput

0.479

High

1288168

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

535515

GFAP
Glial fibrillary acidic protein

1

1

High-throughput

0.470

High

1288151

TTC14
Tetratricopeptide repeat protein 14

1

1

High-throughput

0.464

High

1235768

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

0

High-throughput

0.460

High

1288146

THOC1
THO complex subunit 1

1

0

High-throughput

0.460

High

1288149

CK5P3
CDK5 regulatory subunit-associated protein 3

1

0

High-throughput

0.460

High

1288179

TRAK1
Trafficking kinesin-binding protein 1

1

0

High-throughput

0.460

High

160701

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

163122

XPO1
Exportin-1

1

0

High-throughput

0.458

High

314672

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.458

High

553402

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

611488

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

0

Small-scale

0.458

High

651922

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

668897

PML
Protein PML

1

0

High-throughput

0.458

High

750403

COIL
Coilin

1

0

High-throughput

0.458

High

779894

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

824269

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

831571

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

875214

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

928655

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.458

High

967340

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1027178

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1188698

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1250981

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1266643

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1270369

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.458

High

1288145

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

1288152

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.458

High

1288157

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.458

High

1288159

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1288162

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1288166

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1288172

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1288180

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

1288182

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

68443

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

2

High-throughput

0.445

High

1288167

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

1

High-throughput

0.439

High

1220253

DHX40
Probable ATP-dependent RNA helicase DHX40

1

2

High-throughput

0.437

High

1288160

Q9H4D1
Protein kinase

1

1

High-throughput

0.437

High

321160

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

883598

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

1288148

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

1

High-throughput

0.373

High

1286095

LENG1
Leukocyte receptor cluster member 1

3

0

High-throughput

0.347

High

819171

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

2

0

High-throughput

0.328

High

872980

GALC
Galactocerebrosidase

2

0

High-throughput

0.328

High

926747

CANB1
Calcineurin subunit B type 1

2

0

High-throughput

0.328

High

1020305

ELAV2
ELAV-like protein 2

2

0

High-throughput

0.328

High

1172866

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.328

High

814510

SYQ
Glutamine--tRNA ligase

2

0

High-throughput

0.316

High

1223247

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.316

High

1288161

ARMC7
Armadillo repeat-containing protein 7

2

0

High-throughput

0.316

High

1218342

ARHGJ
Rho guanine nucleotide exchange factor 19

2

0

High-throughput

0.298

High

323953

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

648576

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

1101742

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

1263754

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

246020

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.265

Low

362402

CRP

1

0

High-throughput

0.251

Low

1071325

K1H1
Keratin, type I cuticular Ha1

1

0

High-throughput

0.251

Low

1120287

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.251

Low

1127668

PRC2B
Protein PRRC2B

1

0

High-throughput

0.251

Low

1138138

PR38B
Pre-mRNA-splicing factor 38B

1

0

High-throughput

0.251

Low

1288153

LYST
Lysosomal-trafficking regulator

1

0

Small-scale

0.251

Low

1288173

HOOK1
Protein Hook homolog 1

1

0

High-throughput

0.251

Low

1288181

WNK2
Serine/threonine-protein kinase WNK2

1

0

High-throughput

0.251

Low

101052

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

721125

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

882499

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.249

Low

1200304

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.249

Low

1222511

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.249

Low

1285725

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.249

Low

1287555

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.249

Low

1288155

CP250
Centrosome-associated protein CEP250

1

0

High-throughput

0.249

Low

1288175

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024