Protein: KBTB7
Kelch repeat and BTB domain-containing protein 7

Gene: KBTB7, KBTBD7
Organism: Homo sapiens
Interactions: 221
UniProt ID: Q8WVZ9

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0009968 - negative regulation of signal transduction
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0035020 - regulation of Rac protein signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1042149

CUL3
Cullin-3

12

20

Small-scale

0.977

High

1201284

KBTB6
Kelch repeat and BTB domain-containing protein 6

6

19

Small-scale

0.950

High

1262064

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

4

19

Small-scale

0.909

High

1262066

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

3

19

Small-scale

0.896

High

1245061

KBTB8
Kelch repeat and BTB domain-containing protein 8

3

19

High-throughput

0.876

High

1262088

FXL17
F-box/LRR-repeat protein 17

3

19

High-throughput

0.871

High

891243

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

3

19

Small-scale

0.871

High

306250

GBRAP
Gamma-aminobutyric acid receptor-associated protein

2

19

Small-scale

0.822

High

1262093

ZBT21
Zinc finger and BTB domain-containing protein 21

2

3

High-throughput

0.811

High

1262059

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

2

19

Small-scale

0.792

High

1262043

KLH29
Kelch-like protein 29

2

20

High-throughput

0.726

High

1164620

KLH24
Kelch-like protein 24

1

20

High-throughput

0.691

High

990897

ZO1
Tight junction protein ZO-1

3

4

High-throughput

0.675

High

1262086

PI4KB
Phosphatidylinositol 4-kinase beta

3

2

High-throughput

0.675

High

262523

TULP3
Tubby-related protein 3

3

1

High-throughput

0.667

High

548321

FOSL2
Fos-related antigen 2

3

8

High-throughput

0.667

High

603213

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

3

4

High-throughput

0.667

High

896163

UBC12
NEDD8-conjugating enzyme Ubc12

3

15

High-throughput

0.667

High

1158554

L2GL2
LLGL scribble cell polarity complex component 2

3

3

High-throughput

0.667

High

1237969

ZFP41
Zinc finger protein 41 homolog

3

6

High-throughput

0.667

High

1256931

DOK4
Docking protein 4

3

4

High-throughput

0.667

High

1262044

AP2M1
AP-2 complex subunit mu

3

1

High-throughput

0.667

High

1262062

PAR6B
Partitioning defective 6 homolog beta

3

6

High-throughput

0.667

High

1262100

ARI1
E3 ubiquitin-protein ligase ARIH1

3

13

High-throughput

0.667

High

1262041

NSUN4
5-methylcytosine rRNA methyltransferase NSUN4

4

2

High-throughput

0.643

High

1071549

L2GL1
Lethal(2) giant larvae protein homolog 1

4

2

High-throughput

0.636

High

1220864

PHC2
Polyhomeotic-like protein 2

2

2

High-throughput

0.633

High

116882

KIF2A
Kinesin-like protein KIF2A

2

1

High-throughput

0.628

High

132185

PESC
Pescadillo homolog

2

1

High-throughput

0.628

High

304498

ALX3
Homeobox protein aristaless-like 3

2

3

High-throughput

0.628

High

563792

ZNF3
Zinc finger protein 3

2

1

High-throughput

0.628

High

638358

RBTN2
Rhombotin-2

2

5

High-throughput

0.628

High

664252

TPP2
Tripeptidyl-peptidase 2

2

1

High-throughput

0.628

High

782050

RGS2
Regulator of G-protein signaling 2

2

2

High-throughput

0.628

High

784054

KPCI
Protein kinase C iota type

2

5

High-throughput

0.628

High

814648

CDX1
Homeobox protein CDX-1

2

4

High-throughput

0.628

High

1052116

MAP7
Ensconsin

2

6

High-throughput

0.628

High

1056604

TRIPC
E3 ubiquitin-protein ligase TRIP12

2

2

High-throughput

0.628

High

1059143

HLX
H2.0-like homeobox protein

2

1

High-throughput

0.628

High

1127495

WDR44
WD repeat-containing protein 44

2

4

High-throughput

0.628

High

1169060

ZN574
Zinc finger protein 574

2

1

High-throughput

0.628

High

1199653

ZN598
E3 ubiquitin-protein ligase ZNF598

2

2

High-throughput

0.628

High

1203663

AROS
Active regulator of SIRT1

2

1

High-throughput

0.628

High

1261037

SNX33
Sorting nexin-33

2

8

High-throughput

0.628

High

1262039

ZN669
Zinc finger protein 669

2

2

High-throughput

0.628

High

1262046

ZN414
Zinc finger protein 414

2

5

High-throughput

0.628

High

1262048

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

2

2

High-throughput

0.628

High

1262068

TXNIP
Thioredoxin-interacting protein

2

7

High-throughput

0.628

High

1262077

DCA13
DDB1- and CUL4-associated factor 13

2

2

High-throughput

0.628

High

1262087

ZO2
Tight junction protein ZO-2

2

4

High-throughput

0.628

High

1262092

TNIK
TRAF2 and NCK-interacting protein kinase

2

7

High-throughput

0.628

High

1198041

KAISO
Transcriptional regulator Kaiso

1

5

High-throughput

0.618

High

1222484

SLX4
Structure-specific endonuclease subunit SLX4

1

3

High-throughput

0.618

High

1216132

RB6I2
ELKS/Rab6-interacting/CAST family member 1

3

4

High-throughput

0.616

High

1229651

RBFA
Putative ribosome-binding factor A, mitochondrial

3

1

High-throughput

0.616

High

1262079

TM160
Transmembrane protein 160

3

1

High-throughput

0.616

High

255948

OBSL1
Obscurin-like protein 1

2

7

High-throughput

0.611

High

921360

RBX1
E3 ubiquitin-protein ligase RBX1

2

11

Small-scale

0.611

High

979333

UBXN1
UBX domain-containing protein 1

2

7

Small-scale

0.611

High

1262038

H2B1A
Histone H2B type 1-A

2

2

High-throughput

0.611

High

1074691

SURF2
Surfeit locus protein 2

3

1

High-throughput

0.609

High

1262033

EDA
Ectodysplasin-A

3

2

High-throughput

0.609

High

1262091

KLF15
Krueppel-like factor 15

2

6

High-throughput

0.606

High

948896

SARNP
SAP domain-containing ribonucleoprotein

2

0

High-throughput

0.602

High

1102143

TSR1
Pre-rRNA-processing protein TSR1 homolog

2

0

High-throughput

0.602

High

1192037

MTEF4
Transcription termination factor 4, mitochondrial

2

0

High-throughput

0.602

High

1237369

TSYL6
Testis-specific Y-encoded-like protein 6

2

0

High-throughput

0.602

High

1262037

LMBL2
Lethal(3)malignant brain tumor-like protein 2

2

0

High-throughput

0.602

High

1262052

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

2

0

High-throughput

0.602

High

898981

PSME3
Proteasome activator complex subunit 3

2

0

High-throughput

0.580

High

1262058

CC106
Coiled-coil domain-containing protein 106

2

0

High-throughput

0.580

High

1262027

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

18

High-throughput

0.575

High

215848

ANGL7
Angiopoietin-related protein 7

2

1

High-throughput

0.574

High

256552

ZC11A
Zinc finger CCCH domain-containing protein 11A

2

1

High-throughput

0.574

High

270884

CLC3A
C-type lectin domain family 3 member A

2

1

High-throughput

0.574

High

833633

NUMB
Protein numb homolog

2

5

High-throughput

0.574

High

1147769

SPT2
Protein SPT2 homolog

2

2

High-throughput

0.574

High

1168314

PPR21
Protein phosphatase 1 regulatory subunit 21

2

2

High-throughput

0.574

High

1262045

RT24
Small ribosomal subunit protein uS3m

2

1

High-throughput

0.574

High

1262102

NUMBL
Numb-like protein

2

5

High-throughput

0.574

High

121594

IKBE
NF-kappa-B inhibitor epsilon

1

1

High-throughput

0.541

High

127119

FOXN3
Forkhead box protein N3

1

3

High-throughput

0.536

High

182367

PER1
Period circadian protein homolog 1

1

3

High-throughput

0.536

High

299433

UBXN7
UBX domain-containing protein 7

1

7

High-throughput

0.536

High

345500

FOS
Protein c-Fos

1

8

High-throughput

0.536

High

439351

CATG
Cathepsin G

1

2

High-throughput

0.536

High

471629

TFPT
TCF3 fusion partner

1

1

High-throughput

0.536

High

550415

ZEP1
Zinc finger protein 40

1

2

High-throughput

0.536

High

568034

HXB6
Homeobox protein Hox-B6

1

4

High-throughput

0.536

High

618677

IF4B
Eukaryotic translation initiation factor 4B

1

2

High-throughput

0.536

High

626659

ARBK1
Beta-adrenergic receptor kinase 1

1

4

High-throughput

0.536

High

671882

PDIA3
Protein disulfide-isomerase A3

1

2

High-throughput

0.536

High

809376

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

High-throughput

0.536

High

821335

TCPE
T-complex protein 1 subunit epsilon

1

4

High-throughput

0.536

High

877814

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.536

High

899654

FGF12
Fibroblast growth factor 12

1

6

High-throughput

0.536

High

983883

KPCZ
Protein kinase C zeta type

1

6

High-throughput

0.536

High

997197

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

2

High-throughput

0.536

High

1040001

DGKZ
Diacylglycerol kinase zeta

1

1

High-throughput

0.536

High

1079550

NEDD8
NEDD8

1

3

High-throughput

0.536

High

1132818

OTUD3
OTU domain-containing protein 3

1

1

High-throughput

0.536

High

1135207

RBM26
RNA-binding protein 26

1

2

High-throughput

0.536

High

1157582

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.536

High

1161493

DCNL2
DCN1-like protein 2

1

11

High-throughput

0.536

High

1186121

BHA15
Class A basic helix-loop-helix protein 15

1

3

High-throughput

0.536

High

1216234

H2A2B
Histone H2A type 2-B

1

2

High-throughput

0.536

High

1255824

ES8L1
Epidermal growth factor receptor kinase substrate 8-like protein 1

1

1

High-throughput

0.536

High

1262031

APBP2
Amyloid protein-binding protein 2

1

2

High-throughput

0.536

High

1262034

FGF13
Fibroblast growth factor 13

1

6

High-throughput

0.536

High

1262035

FGF11
Fibroblast growth factor 11

1

6

High-throughput

0.536

High

1262040

ZN524
Zinc finger protein 524

1

3

High-throughput

0.536

High

1262055

PLCD4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

1

2

High-throughput

0.536

High

1262061

PAR6G
Partitioning defective 6 homolog gamma

1

4

High-throughput

0.536

High

1262072

E41L5
Band 4.1-like protein 5

1

3

High-throughput

0.536

High

1262074

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

1

High-throughput

0.536

High

1262076

TBC23
TBC1 domain family member 23

1

2

High-throughput

0.536

High

1262085

IKBL1
NF-kappa-B inhibitor-like protein 1

1

1

High-throughput

0.536

High

1262095

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

1262096

FAF1
FAS-associated factor 1

1

7

High-throughput

0.536

High

1250787

VANG1
Vang-like protein 1

2

1

Small-scale

0.533

High

537297

DRD2
D(2) dopamine receptor

1

2

Small-scale

0.523

High

1046237

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.518

High

1151149

Q6FHY5
MEOX2 protein

1

5

High-throughput

0.515

High

273915

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.513

High

275651

POP7
Ribonuclease P protein subunit p20

1

0

High-throughput

0.513

High

822493

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.513

High

825224

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.513

High

827820

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.513

High

963550

TIAR
Nucleolysin TIAR

1

0

High-throughput

0.513

High

997544

ZN543
Zinc finger protein 543

1

0

High-throughput

0.513

High

1036526

MTM1
Myotubularin

1

0

High-throughput

0.513

High

1120887

PKHO1
Pleckstrin homology domain-containing family O member 1

1

0

High-throughput

0.513

High

1230490

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

High-throughput

0.513

High

1262029

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.513

High

1262032

FAN
Protein FAN

1

0

High-throughput

0.513

High

1262069

BORG4
Cdc42 effector protein 4

1

0

High-throughput

0.513

High

1262073

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.513

High

1262081

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

1262094

VANG2
Vang-like protein 2

1

1

Small-scale

0.512

High

1262051

BARD1
BRCA1-associated RING domain protein 1

1

4

High-throughput

0.508

High

1262057

DUS23
Dual specificity protein phosphatase 23

1

3

High-throughput

0.508

High

49990

PXDNL
Probable oxidoreductase PXDNL

1

2

High-throughput

0.489

High

225934

FGF17
Fibroblast growth factor 17

1

6

High-throughput

0.489

High

265470

PAGE1
P antigen family member 1

1

1

High-throughput

0.489

High

536139

HGF
Hepatocyte growth factor

1

2

High-throughput

0.489

High

589740

CAP7
Azurocidin

1

4

High-throughput

0.489

High

611581

GNLY
Granulysin

1

3

High-throughput

0.489

High

817018

TFPI2
Tissue factor pathway inhibitor 2

1

2

High-throughput

0.489

High

947107

RT25
Small ribosomal subunit protein mS25

1

1

High-throughput

0.489

High

1029190

NOGG
Noggin

1

3

High-throughput

0.489

High

1155862

PHLB3
Pleckstrin homology-like domain family B member 3

1

5

High-throughput

0.489

High

1231740

AN36B
Ankyrin repeat domain-containing protein 36B

1

1

High-throughput

0.489

High

1232259

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

2

High-throughput

0.489

High

1234108

FBXL6
F-box/LRR-repeat protein 6

1

20

High-throughput

0.489

High

1240592

IN80E
INO80 complex subunit E

1

2

High-throughput

0.489

High

1262042

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.489

High

1262060

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

2

High-throughput

0.489

High

1262067

RM18
Large ribosomal subunit protein uL18m

1

1

High-throughput

0.489

High

1262070

GREM2
Gremlin-2

1

1

High-throughput

0.489

High

1262075

EMIL3
EMILIN-3

1

6

High-throughput

0.489

High

1262089

IL17B
Interleukin-17B

1

3

High-throughput

0.489

High

1262097

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

3

High-throughput

0.489

High

838163

MEOX2
Homeobox protein MOX-2

1

6

High-throughput

0.481

High

869399

HAP1
Huntingtin-associated protein 1

1

3

High-throughput

0.481

High

338758

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

432109

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

438396

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

563645

ZNF24
Zinc finger protein 24

1

12

High-throughput

0.479

High

649629

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

908883

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

7

High-throughput

0.479

High

1022427

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

5

Small-scale

0.479

High

1262036

RL36L
Ribosomal protein eL42-like

1

1

High-throughput

0.479

High

1262080

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1262101

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

7

High-throughput

0.479

High

651790

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

1151035

SFRP4
Secreted frizzled-related protein 4

1

0

High-throughput

0.458

High

1240556

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

0

High-throughput

0.458

High

1221886

DDX60
Probable ATP-dependent RNA helicase DDX60

1

2

High-throughput

0.445

High

1133088

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

1

High-throughput

0.439

High

72616

B4DEF8
Large ribosomal subunit protein mL45

1

1

High-throughput

0.437

High

1168985

AEBP2
Zinc finger protein AEBP2

1

5

High-throughput

0.437

High

1246339

THOC2
THO complex subunit 2

1

4

High-throughput

0.437

High

1262084

CE126
Centrosomal protein of 126 kDa

1

1

High-throughput

0.417

High

102371

G3V1M0
Uncharacterized protein DKFZp686H10254

1

5

High-throughput

0.407

High

108796

H0Y7U4
THO complex subunit 2

1

1

High-throughput

0.407

High

483706

CT456
Cancer/testis antigen family 45 member A6

1

1

High-throughput

0.407

High

1262056

RM45
Large ribosomal subunit protein mL45

1

1

High-throughput

0.407

High

1262049

TEFM
Transcription elongation factor, mitochondrial

5

0

High-throughput

0.376

High

63405

MET15
12S rRNA N4-methylcytidine

2

0

High-throughput

0.328

High

271834

CREG1
Protein CREG1

2

0

High-throughput

0.328

High

600974

MK
Midkine

2

0

High-throughput

0.328

High

1059025

LTBP1
Latent-transforming growth factor beta-binding protein 1

2

0

High-throughput

0.328

High

1219511

SULF2
Extracellular sulfatase Sulf-2

2

0

High-throughput

0.328

High

1262047

JPH4
Junctophilin-4

2

0

High-throughput

0.328

High

1262050

CP2S1
Cytochrome P450 2S1

2

0

High-throughput

0.328

High

1262054

RT63
Large ribosomal subunit protein mL63

2

0

High-throughput

0.328

High

1262063

RT26
Small ribosomal subunit protein mS26

2

0

High-throughput

0.328

High

1262065

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

0

High-throughput

0.328

High

1262082

RM27
Large ribosomal subunit protein bL27m

2

0

High-throughput

0.328

High

1262090

MRM2
rRNA methyltransferase 2, mitochondrial

2

0

High-throughput

0.328

High

839334

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.282

High

127540

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.279

Low

823276

MRP
MARCKS-related protein

1

0

High-throughput

0.279

Low

948307

RT34
Small ribosomal subunit protein mS34

1

0

High-throughput

0.279

Low

948645

RT09
Small ribosomal subunit protein uS9m

1

0

High-throughput

0.279

Low

1016394

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.279

Low

1217305

LYSM2
LysM and putative peptidoglycan-binding domain-containing protein 2

1

0

High-throughput

0.279

Low

1219181

BRSK2
Serine/threonine-protein kinase BRSK2

1

0

High-throughput

0.279

Low

1236770

LRC17
Leucine-rich repeat-containing protein 17

1

0

High-throughput

0.279

Low

1253377

RM30
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.279

Low

1253480

DEN10
DENN domain-containing protein 10

1

0

High-throughput

0.279

Low

1259759

SCFD2
Sec1 family domain-containing protein 2

1

0

High-throughput

0.279

Low

1262028

HPSE2
Inactive heparanase-2

1

0

High-throughput

0.279

Low

1262030

RT27
Small ribosomal subunit protein mS27

1

0

High-throughput

0.279

Low

1262053

RM34
Large ribosomal subunit protein bL34m

1

0

High-throughput

0.279

Low

1262098

RT28
Small ribosomal subunit protein bS1m

1

0

High-throughput

0.279

Low

1262099

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

1262071

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.265

Low

1262078

TMM51
Transmembrane protein 51

1

0

High-throughput

0.249

Low

1262083

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024