HitPredict

Interactor 1: GNAO (P16378)
G protein alpha o subunit (Guanine nucleotide-binding protein G(o) subunit alpha 47A)
Gene: Galphao

Interactor 2: Q8T017 (Q8T017)
Double hit, isoform B (LD40005p)
Gene: Dhit

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.80	0.662

Property	Details
Experiments	24560274
Identification Methods	affinity chromatography technology, enzymatic study, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	G-alpha~RGS
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Dm			1 274
+	Hs
		303102 GNAO_HUMAN (1-354): 1.53e-173: 487: 82.20		RGS20_HUMAN (43-268): 2.38e-71: 226: 44.05
+	Hs
		303098 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		RGS20_HUMAN (43-268): 2.38e-71: 226: 44.05
+	Hs
		418623 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		RGS3_HUMAN (105-266): 6.25e-62: 212: 41.36
+	Hs
		297293 GNAO_HUMAN (1-354): 1.53e-173: 487: 82.20		RGS9_HUMAN (111-272): 8.63e-62: 208: 32.32
+	Hs
		418751 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		RGS18_HUMAN (122-274): 1.03e-67: 211: 39.22
+	Hs
		482588 GNAO_HUMAN (1-354): 1.53e-173: 487: 82.20		RGS19_HUMAN (74-268): 1.1e-66: 208: 54.36
+	Hs
		418622 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		RGS19_HUMAN (74-268): 1.1e-66: 208: 54.36
+	Hs
		482589 GNAO_HUMAN (1-354): 1.53e-173: 487: 82.20		RGS4_HUMAN (104-272): 7.29e-65: 203: 36.05
+	Hs
		418624 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		RGS4_HUMAN (104-272): 7.29e-65: 203: 36.05
+	Rn
		533208 GNAI1_RAT (1-354): 1.13e-171: 483: 69.01		RGS4_RAT (104-272): 2.18e-65: 204: 36.05
+	Rn
		890708 GNAO_RAT (1-354): 1e-171: 483: 81.07		RGS4_RAT (104-272): 2.18e-65: 204: 36.05
+	Hs
		168010 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		RGS13_HUMAN (125-266): 6.68e-64: 199: 39.73
+	Hs
		193880 GNAO_HUMAN (1-354): 1.53e-173: 487: 82.20		RGS5_HUMAN (126-259): 3.09e-62: 195: 42.54
+	Hs
		193876 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		RGS5_HUMAN (126-259): 3.09e-62: 195: 42.54
+	Hs
		193887 GNAI1_HUMAN (1-354): 8.5e-172: 483: 69.01		RGS5_HUMAN (126-259): 3.09e-62: 195: 42.54
+	Hs
		192032 GNAO_HUMAN (1-354): 1.53e-173: 487: 82.20		RGS16_HUMAN (124-257): 5.06e-59: 188: 39.55
+	Hs
		220432 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		RGS14_HUMAN (108-272): 2.11e-56: 191: 26.95
+	Hs
		220444 GNAI1_HUMAN (1-354): 8.5e-172: 483: 69.01		RGS14_HUMAN (108-272): 2.11e-56: 191: 26.95
+	Hs
		192029 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		RGS16_HUMAN (124-257): 5.06e-59: 188: 39.55
+	Hs
		192036 GNAI1_HUMAN (1-354): 8.5e-172: 483: 69.01		RGS16_HUMAN (124-257): 5.06e-59: 188: 39.55