HitPredict

Interactor 1: TRX (P20659)
Histone-lysine N-methyltransferase trithorax (EC 2.1.1.355) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Lysine N-methyltransferase 2A)
Gene: TRX

Interactor 2: TRX (P20659)
Histone-lysine N-methyltransferase trithorax (EC 2.1.1.355) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Lysine N-methyltransferase 2A)
Gene: TRX

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.872

The method score is based on:

Property Details
Experiments 24235145, 10656681, 11313484
Identification Methods enzymatic study, two hybrid, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FYRC~FYRN, PHD~PHD, SET~SET
Common GO terms GO:0000123 - histone acetyltransferase complex
GO:0001654 - eye development
GO:0003682 - chromatin binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 20 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 3726
Dm

1 3726
+ Dm
+ At
+ Hs
+ Sc
+ At
+ Hs
+ Mm
+ Hs
+ At
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024