HitPredict

Interactor 1: GNAO (P16378)
G protein alpha o subunit (Guanine nucleotide-binding protein G(o) subunit alpha 47A)
Gene: Galphao

Interactor 2: GBG1 (P38040)
Guanine nucleotide-binding protein subunit gamma-1
Gene: Ggamma1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005834 - heterotrimeric G-protein complex GO:0007186 - G protein-coupled receptor signaling pathway GO:0061343 - cell adhesion involved in heart morphogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Dm			1 70
+	Hs
		482646 GNAO_HUMAN (1-354): 1.53e-173: 487: 82.20		GBG12_HUMAN (5-70): 6.16e-24: 86.6: 39.39
+	Hs
		243462 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		GBG7_HUMAN (5-70): 1.09e-24: 88.6: 37.88
+	Hs
		482595 GNAO_HUMAN (1-354): 1.53e-173: 487: 82.20		GBG2_HUMAN (5-70): 3.14e-23: 85.1: 44.78
+	Hs
		243468 GNAI1_HUMAN (1-354): 8.5e-172: 483: 69.01		GBG7_HUMAN (5-70): 1.09e-24: 88.6: 37.88
+	Hs
		418759 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		GBG12_HUMAN (5-70): 6.16e-24: 86.6: 39.39
+	Hs
		482602 GNAO_HUMAN (1-354): 1.53e-173: 487: 82.20		GBG3_HUMAN (5-70): 2.54e-22: 82.8: 40.30
+	Hs
		989887 GNAI1_HUMAN (1-354): 8.5e-172: 483: 69.01		GBG12_HUMAN (5-70): 6.16e-24: 86.6: 39.39
+	Hs
		418632 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		GBG2_HUMAN (5-70): 3.14e-23: 85.1: 44.78
+	Hs
		948054 GNAI1_HUMAN (1-354): 8.5e-172: 483: 69.01		GBG2_HUMAN (5-70): 3.14e-23: 85.1: 44.78
+	Hs
		482590 GNAO_HUMAN (1-354): 1.53e-173: 487: 82.20		GBG10_HUMAN (6-70): 2.16e-21: 80.1: 35.39
+	Hs
		418646 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		GBG3_HUMAN (5-70): 2.54e-22: 82.8: 40.30
+	Hs
		989826 GNAI1_HUMAN (1-354): 8.5e-172: 483: 69.01		GBG3_HUMAN (5-70): 2.54e-22: 82.8: 40.30
+	Hs
		418625 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		GBG4_HUMAN (5-70): 1.22e-21: 81.2: 40.30
+	Hs
		893553 GNAI1_HUMAN (1-354): 8.5e-172: 483: 69.01		GBG4_HUMAN (5-70): 1.22e-21: 81.2: 40.30
+	Hs
		418626 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		GBG10_HUMAN (6-70): 2.16e-21: 80.1: 35.39
+	Hs
		418647 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		GBG5_HUMAN (5-70): 2.58e-21: 80.1: 39.39
+	Hs
		482650 GNAO_HUMAN (1-354): 1.53e-173: 487: 82.20		GBG8_HUMAN (6-70): 3.73e-20: 77: 33.33
+	Hs
		893567 GNAI1_HUMAN (1-354): 8.5e-172: 483: 69.01		GBG10_HUMAN (6-70): 2.16e-21: 80.1: 35.39
+	Hs
		989827 GNAI1_HUMAN (1-354): 8.5e-172: 483: 69.01		GBG5_HUMAN (5-70): 2.58e-21: 80.1: 39.39
+	Hs
		418762 GNAI2_HUMAN (1-354): 2.92e-172: 484: 67.89		GBG8_HUMAN (6-70): 3.73e-20: 77: 33.33