Protein: Q8T4A9
Exosome complex component RRP45 (Exosome component 9)

Gene: Q8T4A9, Rrp45
Organism: Drosophila melanogaster
Interactions: 64
UniProt ID: Q8T4A9

Gene Ontology (top 5):
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0016075 - rRNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1345951

Q9VC93
Exosome complex exonuclease RRP44

3

20

Small-scale

0.817

High

1177462

Q29QQ9
Ribosomal RNA-processing protein 42

1

17

High-throughput

0.575

High

1305002

EXOS3
Exosome complex component RRP40

1

13

High-throughput

0.575

High

1345953

Q9VGZ2
FI06805p

1

20

High-throughput

0.575

High

1345959

Q9VK19
FI07225p

1

19

High-throughput

0.575

High

1345960

Q9VKJ4
Csl4

1

12

High-throughput

0.575

High

1345973

Q9VW53
FI01414p

1

20

High-throughput

0.575

High

1345980

Q9W1M9
Exosome complex component RRP4

1

20

High-throughput

0.575

High

1345952

EXOSX
Exosome complex component 10 homolog

1

13

High-throughput

0.445

High

54977

A1Z917
PiggyBac transposable element-derived protein domain-containing protein

1

2

High-throughput

0.407

High

56844

A1ZAK3
Protein DEK

1

3

High-throughput

0.407

High

847877

SNRPA
U1 small nuclear ribonucleoprotein A

1

4

High-throughput

0.407

High

925807

SET
Protein SET

1

3

High-throughput

0.407

High

1050905

SSRP1
FACT complex subunit Ssrp1

1

5

High-throughput

0.407

High

1195955

Q4QQ70
IP09819p

1

3

High-throughput

0.407

High

1261396

Q7JQT8
LD41464p

1

2

High-throughput

0.407

High

1264271

Q7K0L8
FLICE-associated huge protein, isoform A

1

3

High-throughput

0.407

High

1264891

Q7K1Q7
Ribosome assembly factor mrt4

1

4

High-throughput

0.407

High

1273691

Q7PLL3
Eukaryotic initiation factor 4B

1

2

High-throughput

0.407

High

1303652

Q8IN95
Nuclear migration protein nudC

1

4

High-throughput

0.407

High

1305523

Q8IQI3
Uncharacterized protein, isoform B

1

2

High-throughput

0.407

High

1306321

SPT16
FACT complex subunit spt16

1

3

High-throughput

0.407

High

1320842

Q8MMD2
Epidermal growth factor receptor pathway substrate clone 15, isoform B

1

3

High-throughput

0.407

High

1321785

Q8MT77
LD28489p

1

3

High-throughput

0.407

High

1343258

Q8SWT2
RNA helicase

1

2

High-throughput

0.407

High

1344565

Q8SYM9
FI04119p

1

2

High-throughput

0.407

High

1345943

EBI
F-box-like/WD repeat-containing protein ebi

1

9

High-throughput

0.407

High

1345944

NASP
Nuclear autoantigenic sperm protein homolog

1

3

High-throughput

0.407

High

1345945

Q9V3D8
GH27579p

1

3

High-throughput

0.407

High

1345946

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

3

High-throughput

0.407

High

1345947

WDS
Protein will die slowly

1

8

High-throughput

0.407

High

1345948

RU2A
Probable U2 small nuclear ribonucleoprotein A'

1

6

High-throughput

0.407

High

1345949

Q9VB04
Protein CASC3

1

1

High-throughput

0.407

High

1345950

Q9VBT1
CHK kinase-like domain-containing protein

1

2

High-throughput

0.407

High

1345954

Q9VHN4
GH14121p

1

2

High-throughput

0.407

High

1345955

RM19
Large ribosomal subunit protein bL19m

1

1

High-throughput

0.407

High

1345956

Q9VHR5
Veneno

1

3

High-throughput

0.407

High

1345957

Q9VHT5
Large ribosomal subunit protein uL1m

1

4

High-throughput

0.407

High

1345958

Q9VIF7
Dynamin associated protein 160, isoform A

1

3

High-throughput

0.407

High

1345961

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

5

High-throughput

0.407

High

1345962

Q9VL60
RE01590p

1

4

High-throughput

0.407

High

1345963

Q9VM14
dihydrolipoyllysine-residue acetyltransferase

1

3

High-throughput

0.407

High

1345964

Q9VNZ3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

3

High-throughput

0.407

High

1345965

RM10
Large ribosomal subunit protein uL10m

1

3

High-throughput

0.407

High

1345966

Q9VPM0
GH06023p

1

3

High-throughput

0.407

High

1345967

Q9VQS4
Spindly

1

2

High-throughput

0.407

High

1345968

DBR1
Lariat debranching enzyme

1

3

High-throughput

0.407

High

1345969

Q9VT38
GH03795p

1

3

High-throughput

0.407

High

1345970

RM39
Large ribosomal subunit protein mL39

1

3

High-throughput

0.407

High

1345971

SMN
Survival motor neuron protein

1

1

High-throughput

0.407

High

1345972

Q9VVF8
Uncharacterized protein, isoform A

1

2

High-throughput

0.407

High

1345974

RUXG
Probable small nuclear ribonucleoprotein G

1

7

High-throughput

0.407

High

1345975

Q9VYT3
FI23714p1

1

5

High-throughput

0.407

High

1345976

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

1

High-throughput

0.407

High

1345977

THUM1
THUMP domain-containing protein 1 homolog

1

2

High-throughput

0.407

High

1345978

Q9W108
FI01540p

1

5

High-throughput

0.407

High

1345979

Q9W1M6
Regulatory protein zeste

1

2

High-throughput

0.407

High

1345981

Q9W3J4
LD35215p

1

3

High-throughput

0.407

High

1345982

Q9W4J4
GM14292p

1

3

High-throughput

0.407

High

1345983

NSUN2
tRNA

1

3

High-throughput

0.407

High

1345984

SYQ
Probable glutamine--tRNA ligase

1

3

High-throughput

0.407

High

1345985

Q9Y134
RNA helicase

1

16

High-throughput

0.407

High

56274

A1ZA18
Kinesin heavy chain 73, isoform A

1

0

High-throughput

0.232

Low

1266542

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025