Interactor 1: EXOS3 (Q8IPX7)
Exosome complex component RRP40 (Ribosomal RNA-processing protein 40)
Gene: Rrp40

Interactor 2: Q8T4A9 (Q8T4A9)
Exosome complex component RRP45 (Exosome component 9)
Gene: Rrp45

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 38944040
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains RNase_PH~Rrp40_N, RNase_PH~RRP40_S1
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0034475 - U4 snRNA 3'-end processing
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 232
Dm

1 412
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Sp
+ Sc
+ At
+ Dm
+ Hs
+ At
+ Sc
+ Sc

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Last updated: 11Aug2025