Protein: DCR2
Endoribonuclease Dcr-2 (Protein Dicer-2) (EC 3.1.26.3)

Gene: DCR2, Dcr-2
Organism: Drosophila melanogaster
Interactions: 34
UniProt ID: A1ZAW0

Gene Ontology (top 5):
GO:0002230 - positive regulation of defense response to virus by host
GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0004386 - helicase activity
GO:0004525 - ribonuclease III activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

57216

Q9VLW8
LD06392p

19

0

Small-scale

0.934

High

57223

AGO2
Protein argonaute-2

3

20

Small-scale

0.853

High

57193

DCR2
Endoribonuclease Dcr-2

1

18

Small-scale

0.618

High

57197

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

6

Small-scale

0.584

High

57200

PP1B
Serine/threonine-protein phosphatase beta isoform

2

6

High-throughput

0.584

High

57218

Q9VMW2
Reticulon-like protein

2

5

High-throughput

0.584

High

57208

Q8T0U6
Serine/threonine-protein phosphatase

2

6

High-throughput

0.570

High

57217

Q9VMV9
Reticulon-like protein

2

5

High-throughput

0.552

High

57210

SRRT
Serrate RNA effector molecule homolog

1

1

Small-scale

0.515

High

57195

M9NFI9
Neurabin-1

1

5

High-throughput

0.484

High

57194

A8JQV1
Uncharacterized protein, isoform C

1

9

High-throughput

0.479

High

57202

NELFE
Negative elongation factor E

1

11

Small-scale

0.479

High

57209

CPSF2
Probable cleavage and polyadenylation specificity factor subunit 2

1

3

Small-scale

0.479

High

57213

CPSF3
Cleavage and polyadenylation specificity factor 73

1

3

Small-scale

0.479

High

57214

ELP1
Elongator complex protein 1

1

1

Small-scale

0.479

High

57222

SMD1
Probable small nuclear ribonucleoprotein Sm D1

1

6

Small-scale

0.479

High

57224

GLD2B
Poly(A) RNA polymerase gld-2 homolog B

1

1

Small-scale

0.479

High

57225

Q9W1I0
TAR DNA-binding protein 43

1

20

Small-scale

0.479

High

57201

TAF11
Transcription initiation factor TFIID subunit 11

1

0

Small-scale

0.458

High

57207

SYMPK
Symplekin

1

0

Small-scale

0.458

High

57219

Q9VP13
Large ribosomal subunit protein mL64

1

0

Small-scale

0.458

High

57196

TENM
Teneurin-m

1

1

High-throughput

0.445

High

57198

SGG
Protein kinase shaggy

1

9

High-throughput

0.445

High

57199

FAS2
Fasciclin-2

1

2

High-throughput

0.445

High

57204

Q4V467
IP10845p

1

9

High-throughput

0.445

High

57206

Q8IRE7
PAN2-PAN3 deadenylation complex subunit PAN3

1

4

High-throughput

0.445

High

57215

Q9VJ30
non-specific serine/threonine protein kinase

1

6

High-throughput

0.445

High

57220

COLD
UPAR/Ly6 domain-containing protein cold

1

1

High-throughput

0.445

High

57221

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

6

High-throughput

0.445

High

57212

Q9VCC9
LD23779p

1

5

High-throughput

0.437

High

57203

DALY
Division abnormally delayed protein

1

1

High-throughput

0.407

High

57211

Q9V9S0
FI04419p

1

0

High-throughput

0.253

Low

57205

Q7K3W4
GH08941p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025