Protein: KDM1A
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2)

Gene: KDM1A
Organism: Mus musculus
Interactions: 218
UniProt ID: Q6ZQ88

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1169746

RCOR1
REST corepressor 1

4

16

Small-scale

0.878

High

1169742

RCOR2
REST corepressor 2

3

16

Small-scale

0.827

High

1161359

RCOR3
REST corepressor 3

2

14

High-throughput

0.754

High

140287

HDAC1
Histone deacetylase 1

5

10

Small-scale

0.706

High

590390

PO5F1
POU domain, class 5, transcription factor 1

4

3

High-throughput

0.697

High

936408

HDAC2
Histone deacetylase 2

4

10

Small-scale

0.683

High

1169776

RING2
E3 ubiquitin-protein ligase RING2

3

6

Small-scale

0.662

High

292172

CTBP1
C-terminal-binding protein 1

3

3

Small-scale

0.646

High

1161068

CHD4
Chromodomain-helicase-DNA-binding protein 4

3

8

Small-scale

0.646

High

580483

ANDR
Androgen receptor

2

12

Small-scale

0.619

High

823146

MYBB
Myb-related protein B

1

1

High-throughput

0.618

High

1169708

KDM1A
Lysine-specific histone demethylase 1A

1

6

High-throughput

0.618

High

1169771

MTA3
Metastasis-associated protein MTA3

1

14

High-throughput

0.618

High

1169803

NCOR2
Nuclear receptor corepressor 2

1

15

High-throughput

0.618

High

1169719

NANOG
Homeobox protein NANOG

2

2

Small-scale

0.611

High

250553

GFI1B
Zinc finger protein Gfi-1b

1

7

Small-scale

0.586

High

1169759

KDM4C
Lysine-specific demethylase 4C

1

3

Small-scale

0.586

High

881364

CTBP2
C-terminal-binding protein 2

2

3

High-throughput

0.584

High

1112504

RREB1
Ras-responsive element-binding protein 1

2

2

High-throughput

0.584

High

1112518

Q3UH63
Scm-like with four mbt domains 2

2

12

High-throughput

0.584

High

1113374

KDM5A
Lysine-specific demethylase 5A

2

3

High-throughput

0.584

High

1145161

ZEB1
Zinc finger E-box-binding homeobox 1

2

8

Small-scale

0.584

High

1169606

PF21A
PHD finger protein 21A

2

12

High-throughput

0.584

High

1169690

Q6ZQ47
MKIAA0784 protein

2

1

High-throughput

0.584

High

1169711

ZN516
Zinc finger protein 516

2

3

High-throughput

0.584

High

1169777

ZMYM2
Zinc finger MYM-type protein 2

2

7

High-throughput

0.584

High

1169804

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

2

10

High-throughput

0.584

High

193149

FOG1
Zinc finger protein ZFPM1

1

3

Small-scale

0.554

High

604011

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

2

Small-scale

0.536

High

949331

TNIK
Traf2 and NCK-interacting protein kinase

1

1

High-throughput

0.536

High

1113050

TF2L1
Transcription factor CP2-like protein 1

1

1

High-throughput

0.536

High

1158233

KDM2B
Lysine-specific demethylase 2B

1

1

Small-scale

0.536

High

1169788

TSC1
Hamartin

1

6

High-throughput

0.536

High

1112359

GSE1
Genetic suppressor element 1

2

1

High-throughput

0.533

High

862837

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

Small-scale

0.500

High

56879

A2A7F4
Rearranged L-myc fusion sequence

1

4

High-throughput

0.479

High

57556

LRP2
Low-density lipoprotein receptor-related protein 2

1

1

High-throughput

0.479

High

60486

A5D6Q2
Ncoa3 protein

1

3

High-throughput

0.479

High

64756

ZSC4D
Zinc finger and SCAN domain containing protein 4D

1

9

High-throughput

0.479

High

82783

B9EKQ3
Prdm2 protein

1

3

High-throughput

0.479

High

88331

SAMD1
Sterile alpha motif domain-containing protein 1

1

3

High-throughput

0.479

High

93320

PRR12
Proline-rich protein 12

1

5

High-throughput

0.479

High

93408

E9Q3G0
Zinc finger and SCAN domain containing 4B

1

8

High-throughput

0.479

High

93739

E9QA23
Zinc finger protein 644

1

1

High-throughput

0.479

High

93833

E9QMD3
Zinc finger homeobox 3

1

1

High-throughput

0.479

High

101555

F8VQG7
NEDD4 binding protein 2

1

1

High-throughput

0.479

High

102325

G3UW90
Transcriptional repressor GATA binding 1

1

7

High-throughput

0.479

High

103642

G5E8N3
SET domain, bifurcated 1

1

5

High-throughput

0.479

High

140051

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

4

High-throughput

0.479

High

192532

CHK1
Serine/threonine-protein kinase Chk1

1

1

High-throughput

0.479

High

223236

SPT5H
Transcription elongation factor SPT5

1

3

High-throughput

0.479

High

291342

WIZ
Protein Wiz

1

4

High-throughput

0.479

High

548974

NDKA
Nucleoside diphosphate kinase A

1

1

High-throughput

0.479

High

669126

NEDD8
NEDD8

1

3

High-throughput

0.479

High

675607

HMGB2
High mobility group protein B2

1

9

High-throughput

0.479

High

678832

SUH
Recombining binding protein suppressor of hairless

1

1

Small-scale

0.479

High

817491

RFX1
MHC class II regulatory factor RFX1

1

2

High-throughput

0.479

High

824602

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

869040

ATX1
Ataxin-1

1

1

High-throughput

0.479

High

869797

MSH6
DNA mismatch repair protein Msh6

1

2

High-throughput

0.479

High

885727

FOXP1
Forkhead box protein P1

1

3

High-throughput

0.479

High

926291

DNJA1
DnaJ homolog subfamily A member 1

1

1

High-throughput

0.479

High

928554

DYL1
Dynein light chain 1, cytoplasmic

1

2

High-throughput

0.479

High

956192

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

959179

PIT1
Pituitary-specific positive transcription factor 1

1

4

Small-scale

0.479

High

966382

NDKB
Nucleoside diphosphate kinase B

1

1

High-throughput

0.479

High

970216

PLAK
Junction plakoglobin

1

1

High-throughput

0.479

High

993668

TLE3
Transducin-like enhancer protein 3

1

6

High-throughput

0.479

High

1112180

Q3U0X6
Zinc finger protein 217

1

3

High-throughput

0.479

High

1112256

DDB1
DNA damage-binding protein 1

1

1

Small-scale

0.479

High

1112334

LCORL
Ligand-dependent nuclear receptor corepressor-like protein

1

1

High-throughput

0.479

High

1112336

ZMYM5
Zinc finger MYM-type protein 5

1

6

High-throughput

0.479

High

1112449

Q3UCL2
RING-type E3 ubiquitin transferase

1

3

High-throughput

0.479

High

1112509

Q3UH28
Zinc finger, MYND-type containing 8

1

7

High-throughput

0.479

High

1112901

MCAF2
Activating transcription factor 7-interacting protein 2

1

1

High-throughput

0.479

High

1113209

TET1
Methylcytosine dioxygenase TET1

1

2

High-throughput

0.479

High

1113228

ZSC4F
Zinc finger and SCAN domain containing protein 4F

1

10

High-throughput

0.479

High

1117011

TET2
Methylcytosine dioxygenase TET2

1

2

High-throughput

0.479

High

1119767

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

6

High-throughput

0.479

High

1122671

ZN608
Zinc finger protein 608

1

4

High-throughput

0.479

High

1142101

NR0B1
Nuclear receptor subfamily 0 group B member 1

1

14

High-throughput

0.479

High

1142666

ERR2
Steroid hormone receptor ERR2

1

8

High-throughput

0.479

High

1142955

ZN148
Zinc finger protein 148

1

3

High-throughput

0.479

High

1143957

TLE1
Transducin-like enhancer protein 1

1

6

High-throughput

0.479

High

1143963

TLE4
Transducin-like enhancer protein 4

1

6

High-throughput

0.479

High

1144857

PHC1
Polyhomeotic-like protein 1

1

16

High-throughput

0.479

High

1145005

NR2E1
Nuclear receptor subfamily 2 group E member 1

1

9

Small-scale

0.479

High

1145012

TIF1A
Transcription intermediary factor 1-alpha

1

6

High-throughput

0.479

High

1148417

Z280D
Zinc finger protein 280D

1

6

High-throughput

0.479

High

1149450

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

High-throughput

0.479

High

1157158

ZN532
Zinc finger protein 532

1

4

High-throughput

0.479

High

1169598

LCOR
Ligand-dependent corepressor

1

1

Small-scale

0.479

High

1169626

Q6ZPV6
MKIAA1227 protein

1

4

High-throughput

0.479

High

1169712

NACC1
Nucleus accumbens-associated protein 1

1

6

High-throughput

0.479

High

1169713

MCAF1
Activating transcription factor 7-interacting protein 1

1

6

High-throughput

0.479

High

1169714

RERE
Arginine-glutamic acid dipeptide repeats protein

1

10

High-throughput

0.479

High

1169715

ZSC4C
Zinc finger and SCAN domain containing protein 4C

1

8

High-throughput

0.479

High

1169716

HOMEZ
Homeobox and leucine zipper protein Homez

1

3

High-throughput

0.479

High

1169717

KDM5B
Lysine-specific demethylase 5B

1

3

High-throughput

0.479

High

1169718

CTIP
DNA endonuclease RBBP8

1

2

High-throughput

0.479

High

1169721

TXNIP
Thioredoxin-interacting protein

1

3

High-throughput

0.479

High

1169724

ZN592
Zinc finger protein 592

1

3

High-throughput

0.479

High

1169726

Q8BK32
Nuclear receptor corepressor 1

1

2

High-throughput

0.479

High

1169728

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

12

High-throughput

0.479

High

1169729

ARI5B
AT-rich interactive domain-containing protein 5B

1

4

High-throughput

0.479

High

1169731

KAISO
Transcriptional regulator Kaiso

1

6

High-throughput

0.479

High

1169732

Q8BNK5
C2H2-type domain-containing protein

1

7

High-throughput

0.479

High

1169734

Q8BPK8
Agenet-like domain-containing protein

1

1

High-throughput

0.479

High

1169735

TRI14
Tripartite motif-containing protein 14

1

6

High-throughput

0.479

High

1169736

TREF1
Transcriptional-regulating factor 1

1

16

High-throughput

0.479

High

1169737

ZN609
Zinc finger protein 609

1

1

High-throughput

0.479

High

1169738

POGZ
Pogo transposable element with ZNF domain

1

6

High-throughput

0.479

High

1169741

PIAS2
E3 SUMO-protein ligase PIAS2

1

1

High-throughput

0.479

High

1169744

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

12

High-throughput

0.479

High

1169747

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.479

High

1169748

BCOR
BCL-6 corepressor

1

7

High-throughput

0.479

High

1169749

TSH3
Teashirt homolog 3

1

3

High-throughput

0.479

High

1169750

PHC3
Polyhomeotic-like protein 3

1

13

High-throughput

0.479

High

1169754

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

6

High-throughput

0.479

High

1169755

ZN131
Zinc finger protein 131

1

8

High-throughput

0.479

High

1169758

PSPC1
Paraspeckle component 1

1

2

High-throughput

0.479

High

1169760

ELF5
ETS-related transcription factor Elf-5

1

1

High-throughput

0.479

High

1169761

RCC1
Regulator of chromosome condensation

1

3

High-throughput

0.479

High

1169762

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

1169763

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

5

High-throughput

0.479

High

1169765

ZKSC3
Zinc finger protein with KRAB and SCAN domains 3

1

5

High-throughput

0.479

High

1169766

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

1

High-throughput

0.479

High

1169768

EED
Polycomb protein EED

1

5

High-throughput

0.479

High

1169769

CIC
Protein capicua homolog

1

7

High-throughput

0.479

High

1169770

XPO5
Exportin-5

1

1

High-throughput

0.479

High

1169772

FOXP3
Forkhead box protein P3

1

4

High-throughput

0.479

High

1169773

UBQL4
Ubiquilin-4

1

2

High-throughput

0.479

High

1169778

SGT1
Protein SGT1 homolog

1

5

High-throughput

0.479

High

1169785

HM20A
High mobility group protein 20A

1

10

High-throughput

0.479

High

1169786

Q9DCC5
Cbx3 protein

1

6

High-throughput

0.479

High

1169790

TCF20
Transcription factor 20

1

7

High-throughput

0.479

High

1169792

PKHA2
Pleckstrin homology domain-containing family A member 2

1

1

High-throughput

0.479

High

1169794

GTF2I
General transcription factor II-I

1

1

High-throughput

0.479

High

1169795

ZMYM3
Zinc finger MYM-type protein 3

1

7

High-throughput

0.479

High

1169796

SMBT1
Scm-like with four MBT domains protein 1

1

13

High-throughput

0.479

High

1169797

CAF1A
Chromatin assembly factor 1 subunit A

1

3

High-throughput

0.479

High

1169798

PHC2
Polyhomeotic-like protein 2

1

15

High-throughput

0.479

High

1169800

ZEB2
Zinc finger E-box-binding homeobox 2

1

8

High-throughput

0.479

High

1169801

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

5

High-throughput

0.479

High

1169802

FIZ1
Flt3-interacting zinc finger protein 1

1

1

High-throughput

0.479

High

1169805

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

7

High-throughput

0.479

High

1169806

RED
Protein Red

1

1

High-throughput

0.479

High

69861

ZN462
Zinc finger protein 462

1

0

High-throughput

0.458

High

93880

E9QPI5
PDS5 cohesin associated factor A

1

0

High-throughput

0.458

High

444972

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

485953

MYOD1
Myoblast determination protein 1

1

0

Small-scale

0.458

High

622993

LKHA4
Leukotriene A-4 hydrolase

1

0

High-throughput

0.458

High

818855

PROX1
Prospero homeobox protein 1

1

0

High-throughput

0.458

High

981541

CO6A1

1

0

High-throughput

0.458

High

996143

TFDP1
Transcription factor Dp-1

1

0

High-throughput

0.458

High

1123035

LIN54
Protein lin-54 homolog

1

0

High-throughput

0.458

High

1142523

AP2C
Transcription factor AP-2 gamma

1

0

High-throughput

0.458

High

1144401

MEF2D
Myocyte-specific enhancer factor 2D

1

0

Small-scale

0.458

High

1149096

JHD2C
Probable JmjC domain-containing histone demethylation protein 2C

1

0

High-throughput

0.458

High

1160367

SPCS
O-phosphoseryl-tRNA(Sec) selenium transferase

1

0

High-throughput

0.458

High

1160655

KIF11
Kinesin-like protein KIF11

1

0

High-throughput

0.458

High

1169630

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.458

High

1169709

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.458

High

1169720

RUSC1
AP-4 complex accessory subunit RUSC1

1

0

High-throughput

0.458

High

1169722

BOLA2
BolA-like protein 2

1

0

High-throughput

0.458

High

1169727

TF3C2
General transcription factor 3C polypeptide 2

1

0

High-throughput

0.458

High

1169743

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.458

High

1169764

DDX1
ATP-dependent RNA helicase DDX1

1

0

High-throughput

0.458

High

1169767

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.458

High

1169774

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.458

High

1169784

TF3C6
General transcription factor 3C polypeptide 6

1

0

High-throughput

0.458

High

1169787

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.458

High

1169791

INP4A
Inositol polyphosphate-4-phosphatase type I A

1

0

High-throughput

0.458

High

729525

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.445

High

56875

ZMYM4
Zinc finger MYM-type protein 4

1

6

High-throughput

0.437

High

88483

GLSK
Glutaminase kidney isoform, mitochondrial

1

1

High-throughput

0.437

High

93231

E9PW10
Tripartite motif family-like 2

1

5

High-throughput

0.437

High

93560

DESP
Desmoplakin

1

6

High-throughput

0.437

High

101561

F8VQJ3
Laminin, gamma 1

1

1

High-throughput

0.437

High

102640

G3X928
Sec23 interacting protein

1

2

High-throughput

0.437

High

589639

VIME
Vimentin

1

6

High-throughput

0.437

High

1103780

S39A7
Zinc transporter SLC39A7

1

1

High-throughput

0.437

High

1112001

Q3TMP1
General transcription factor IIIC, polypeptide 3

1

3

High-throughput

0.437

High

1112526

Q3UH85
Nucleolar protein 4-like

1

1

High-throughput

0.437

High

1143244

CP131
Centrosomal protein of 131 kDa

1

6

High-throughput

0.437

High

1169710

EMAL2
Echinoderm microtubule-associated protein-like 2

1

3

High-throughput

0.437

High

1169723

CDC23
Cell division cycle protein 23 homolog

1

4

High-throughput

0.437

High

1169733

Q8BNP7
Adenomatous polyposis coli N-terminal dimerisation domain-containing protein

1

1

High-throughput

0.437

High

1169739

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.437

High

1169740

K1958
Uncharacterized protein KIAA1958 homolog

1

6

High-throughput

0.437

High

1169745

Q8CEB4
DNA endonuclease Ctp1 N-terminal domain-containing protein

1

2

High-throughput

0.437

High

1169775

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.437

High

1169779

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.437

High

1169780

Q9D0K8
C2H2 AKAP95-type domain-containing protein

1

1

High-throughput

0.437

High

1169781

ERP44
Endoplasmic reticulum resident protein 44

1

1

High-throughput

0.437

High

1169782

ZN687
Zinc finger protein 687

1

3

High-throughput

0.437

High

1169793

RBP2
E3 SUMO-protein ligase RanBP2

1

1

High-throughput

0.437

High

1169799

PLEC
Plectin

1

5

High-throughput

0.437

High

1169789

XPO7
Exportin-7

1

1

High-throughput

0.407

High

82725

GRB1L
GREB1-like protein

1

0

High-throughput

0.249

Low

192548

DHX15
ATP-dependent RNA helicase DHX15

1

0

High-throughput

0.249

Low

292626

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.249

Low

535742

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.249

Low

822753

FOLC
Folylpolyglutamate synthase, mitochondrial

1

0

High-throughput

0.249

Low

950910

AP2M1
AP-2 complex subunit mu

1

0

High-throughput

0.249

Low

1103598

MSTO1
Protein misato homolog 1

1

0

High-throughput

0.249

Low

1113399

Q3UZG4
Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

1

0

High-throughput

0.249

Low

1141814

IF1A
Eukaryotic translation initiation factor 1A

1

0

High-throughput

0.249

Low

1157875

MSD2
Myb/SANT-like DNA-binding domain-containing protein 2

1

0

High-throughput

0.249

Low

1169725

AL14E
ARL14 effector protein

1

0

High-throughput

0.249

Low

1169730

TF3C4
General transcription factor 3C polypeptide 4

1

0

High-throughput

0.249

Low

1169751

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.249

Low

1169752

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.249

Low

1169753

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.249

Low

1169756

SPNS1
Protein spinster homolog 1

1

0

High-throughput

0.249

Low

1169757

TF3C5
General transcription factor 3C polypeptide 5

1

0

High-throughput

0.249

Low

1169783

IDH3A
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024