Protein: SMUF2
E3 ubiquitin-protein ligase SMURF2 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF2) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2)

Gene: SMUF2, Smurf2
Organism: Mus musculus
Interactions: 15
UniProt ID: A2A5Z6

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

59022

SMAD7
Mothers against decapentaplegic homolog 7

3

20

Small-scale

0.640

High

59035

PAR6A
Partitioning defective 6 homolog alpha

1

15

Small-scale

0.536

High

59025

SMAD1
Mothers against decapentaplegic homolog 1

2

20

Small-scale

0.533

High

59023

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

20

Small-scale

0.515

High

59024

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.515

High

59027

RUNX2
Runt-related transcription factor 2

1

11

Small-scale

0.479

High

59028

SKIL
Ski-like protein

1

4

Small-scale

0.479

High

59029

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

20

Small-scale

0.479

High

59030

TGFR1
TGF-beta receptor type-1

1

19

Small-scale

0.479

High

59026

TP53B
TP53-binding protein 1

1

7

Small-scale

0.470

High

59021

E9Q509
Pyruvate kinase

1

5

Small-scale

0.437

High

59031

Q6GTZ3
Idb1 protein

1

3

Small-scale

0.437

High

59033

SETD7
Histone-lysine N-methyltransferase SETD7

1

5

Small-scale

0.437

High

59032

NKD2
Protein naked cuticle homolog 2

1

0

Small-scale

0.269

Low

59034

PROK2
Prokineticin-2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025