Protein: LRP5
Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7)

Gene: LRP5
Organism: Homo sapiens
Interactions: 95
UniProt ID: O75197

Gene Ontology (top 5):
GO:0001702 - gastrulation with mouth forming second
GO:0002053 - positive regulation of mesenchymal cell proliferation
GO:0002076 - osteoblast development
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

258340

SOST
Sclerostin

4

6

Small-scale

0.896

High

258286

FA9
Coagulation factor IX

2

7

High-throughput

0.811

High

258324

SPA12
Serpin A12

2

1

High-throughput

0.811

High

258313

SUSD4
Sushi domain-containing protein 4

3

4

High-throughput

0.770

High

59821

PRS37
Probable inactive serine protease 37

2

19

High-throughput

0.726

High

158877

NCTR3
Natural cytotoxicity triggering receptor 3

1

2

High-throughput

0.691

High

258344

SIRPD
Signal-regulatory protein delta

1

2

High-throughput

0.691

High

258318

BRNP3
BMP/retinoic acid-inducible neural-specific protein 3

2

0

High-throughput

0.679

High

258282

DKK1
Dickkopf-related protein 1

3

8

High-throughput

0.667

High

258298

ETV6
Transcription factor ETV6

3

1

High-throughput

0.667

High

258329

PAR16
Protein mono-ADP-ribosyltransferase PARP16

3

1

High-throughput

0.667

High

258333

LIPH
Lipase member H

3

6

High-throughput

0.667

High

258338

RHES
GTP-binding protein Rhes

3

6

High-throughput

0.667

High

170583

AXIN1
Axin-1

3

5

Small-scale

0.640

High

258348

SG196
Protein O-mannose kinase

4

1

High-throughput

0.638

High

258349

LRC4C
Leucine-rich repeat-containing protein 4C

2

3

High-throughput

0.628

High

258360

DKKL1
Dickkopf-like protein 1

2

1

High-throughput

0.628

High

257241

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

5

High-throughput

0.618

High

258288

KLK3
Prostate-specific antigen

1

15

High-throughput

0.618

High

258345

KLK15
Kallikrein-15

1

11

High-throughput

0.618

High

258362

KLK5
Kallikrein-5

1

11

High-throughput

0.618

High

258281

LRP6
Low-density lipoprotein receptor-related protein 6

1

9

Small-scale

0.618

High

258309

TAZ
Tafazzin

3

4

High-throughput

0.609

High

258319

CHST9
Carbohydrate sulfotransferase 9

3

1

High-throughput

0.609

High

258314

CAPR2
Caprin-2

1

4

Small-scale

0.578

High

258283

NXPH2
Neurexophilin-2

2

1

High-throughput

0.574

High

258284

SG1D1
Secretoglobin family 1D member 1

2

3

High-throughput

0.574

High

258299

KC1A
Casein kinase I isoform alpha

2

4

High-throughput

0.574

High

258300

FCGRN
IgG receptor FcRn large subunit p51

2

5

High-throughput

0.574

High

258320

PODN
Podocan

2

2

High-throughput

0.574

High

258321

TF2LY
Homeobox protein TGIF2LY

2

1

High-throughput

0.574

High

258335

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

5

High-throughput

0.574

High

258342

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

8

High-throughput

0.574

High

258356

MGT4C
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

2

2

High-throughput

0.574

High

258358

DKK4
Dickkopf-related protein 4

2

8

High-throughput

0.574

High

215777

B3GT2
Beta-1,3-galactosyltransferase 2

2

4

High-throughput

0.558

High

135519

WN10B
Protein Wnt-10b

1

13

High-throughput

0.536

High

258285

LGI1
Leucine-rich glioma-inactivated protein 1

1

5

High-throughput

0.536

High

258289

CFC1
Cryptic protein

1

2

High-throughput

0.536

High

258291

EDN3
Endothelin-3

1

3

High-throughput

0.536

High

258295

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

1

High-throughput

0.536

High

258307

IL5RA
Interleukin-5 receptor subunit alpha

1

6

High-throughput

0.536

High

258327

LYPD1
Ly6/PLAUR domain-containing protein 1

1

1

High-throughput

0.536

High

258328

RNF10
E3 ubiquitin-protein ligase RNF10

1

1

High-throughput

0.536

High

258336

CLC2B
C-type lectin domain family 2 member B

1

2

High-throughput

0.536

High

258343

WN10A
Protein Wnt-10a

1

13

High-throughput

0.536

High

258350

SDF2L
Stromal cell-derived factor 2-like protein 1

1

2

High-throughput

0.536

High

258357

DNJB9
DnaJ homolog subfamily B member 9

1

2

High-throughput

0.536

High

258361

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

8

High-throughput

0.536

High

258364

LIPG
Endothelial lipase

1

6

High-throughput

0.536

High

258323

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.513

High

258332

TM87A
Transmembrane protein 87A

1

0

High-throughput

0.513

High

258346

FZD8
Frizzled-8

1

4

Small-scale

0.501

High

258326

APCD1
Protein APCDD1

1

0

Small-scale

0.493

High

180111

SIA8E
Alpha-2,8-sialyltransferase 8E

1

5

High-throughput

0.489

High

211335

PI15
Peptidase inhibitor 15

1

5

High-throughput

0.489

High

258290

PRG2
Bone marrow proteoglycan

1

5

High-throughput

0.489

High

258293

CRIS2
Cysteine-rich secretory protein 2

1

5

High-throughput

0.489

High

258297

TIMP3
Metalloproteinase inhibitor 3

1

4

High-throughput

0.489

High

258308

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

1

5

High-throughput

0.489

High

258311

DB135
Beta-defensin 135

1

1

High-throughput

0.489

High

258312

NMS
Neuromedin-S

1

2

High-throughput

0.489

High

258315

LYZL1
Lysozyme-like protein 1

1

3

High-throughput

0.489

High

258316

IGFL3
Insulin growth factor-like family member 3

1

6

High-throughput

0.489

High

258317

CHSS3
Chondroitin sulfate synthase 3

1

4

High-throughput

0.489

High

258325

NRSN1
Neurensin-1

1

1

High-throughput

0.489

High

258330

KC1AL
Casein kinase I isoform alpha-like

1

4

High-throughput

0.489

High

258331

ZN383
Zinc finger protein 383

1

11

High-throughput

0.489

High

258337

CCL17
C-C motif chemokine 17

1

2

High-throughput

0.489

High

258341

OVOL2
Transcription factor Ovo-like 2

1

19

High-throughput

0.489

High

258351

GPTC2
G patch domain-containing protein 2

1

1

High-throughput

0.489

High

258355

DNM3B
DNA

1

1

High-throughput

0.489

High

258359

DKK2
Dickkopf-related protein 2

1

8

High-throughput

0.489

High

171349

SMAD9
Mothers against decapentaplegic homolog 9

1

0

High-throughput

0.486

High

204822

TGON2
Trans-Golgi network integral membrane protein 2

1

8

High-throughput

0.479

High

258292

RAC2
Ras-related C3 botulinum toxin substrate 2

1

10

High-throughput

0.479

High

258296

CTNB1
Catenin beta-1

1

3

Small-scale

0.479

High

258302

RAC3
Ras-related C3 botulinum toxin substrate 3

1

12

High-throughput

0.479

High

258303

CDC42
Cell division control protein 42 homolog

1

12

High-throughput

0.479

High

258304

RHOA
Transforming protein RhoA

1

12

High-throughput

0.479

High

258305

RAC1
Ras-related C3 botulinum toxin substrate 1

1

12

High-throughput

0.479

High

258347

RHOJ
Rho-related GTP-binding protein RhoJ

1

15

High-throughput

0.479

High

258352

ELOV5
Very long chain fatty acid elongase 5

1

3

High-throughput

0.479

High

258363

TRAF6
TNF receptor-associated factor 6

1

4

Small-scale

0.479

High

258306

NDP
Norrin

1

2

Small-scale

0.445

High

258354

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.437

High

258287

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

258301

FAM3B
Protein FAM3B

2

0

High-throughput

0.328

High

258310

ODAPH
Odontogenesis associated phosphoprotein

2

0

High-throughput

0.328

High

58571

COLL1
Colipase-like protein 1

1

0

High-throughput

0.279

Low

258322

RBM45
RNA-binding protein 45

1

0

High-throughput

0.279

Low

258334

DNS2B
Deoxyribonuclease-2-beta

1

0

High-throughput

0.279

Low

258339

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

258353

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.279

Low

258294

STMN1
Stathmin

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024