Protein: PRRT2
Proline-rich transmembrane protein 2 (Dispanin subfamily B member 3) (DSPB3)

Gene: PRRT2
Organism: Mus musculus
Interactions: 209
UniProt ID: E9PUL5

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0008021 - synaptic vesicle
GO:0016020 - membrane
GO:0017075 - syntaxin-1 binding
GO:0017124 - SH3 domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

97332

STX1A
Syntaxin-1A

1

7

High-throughput

0.561

High

97399

VAMP2
Vesicle-associated membrane protein 2

1

1

High-throughput

0.561

High

97423

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

12

High-throughput

0.536

High

72834

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

1

High-throughput

0.479

High

73957

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

8

High-throughput

0.479

High

97328

PHB2
Prohibitin-2

1

1

High-throughput

0.479

High

97330

PRRT1
Proline-rich transmembrane protein 1

1

3

High-throughput

0.479

High

97333

SYT3
Synaptotagmin-3

1

4

High-throughput

0.479

High

97335

SNG1
Synaptogyrin-1

1

2

High-throughput

0.479

High

97336

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

5

High-throughput

0.479

High

97338

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

8

High-throughput

0.479

High

97343

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

8

High-throughput

0.479

High

97344

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

5

High-throughput

0.479

High

97347

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

2

High-throughput

0.479

High

97350

NTRK2
BDNF/NT-3 growth factors receptor

1

12

High-throughput

0.479

High

97351

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

1

High-throughput

0.479

High

97352

KCNA1
Potassium voltage-gated channel subfamily A member 1

1

8

High-throughput

0.479

High

97353

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

8

High-throughput

0.479

High

97354

AP2A2
AP-2 complex subunit alpha-2

1

8

High-throughput

0.479

High

97356

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

1

8

High-throughput

0.479

High

97357

MAG
Myelin-associated glycoprotein

1

4

High-throughput

0.479

High

97358

GBRG2
Gamma-aminobutyric acid receptor subunit gamma-2

1

1

High-throughput

0.479

High

97359

GRIA2
Glutamate receptor 2

1

1

High-throughput

0.479

High

97360

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

8

High-throughput

0.479

High

97362

SSR3
Somatostatin receptor type 3

1

7

High-throughput

0.479

High

97363

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

1

High-throughput

0.479

High

97366

CD81
CD81 antigen

1

3

High-throughput

0.479

High

97367

DYN1
Dynamin-1

1

2

High-throughput

0.479

High

97368

DYN2
Dynamin-2

1

2

High-throughput

0.479

High

97369

EAA2
Excitatory amino acid transporter 2

1

3

High-throughput

0.479

High

97371

ITAV
Integrin alpha-V

1

1

High-throughput

0.479

High

97372

SYT1
Synaptotagmin-1

1

4

High-throughput

0.479

High

97373

SYT2
Synaptotagmin-2

1

4

High-throughput

0.479

High

97374

CNR1
Cannabinoid receptor 1

1

5

High-throughput

0.479

High

97378

EAA1
Excitatory amino acid transporter 1

1

3

High-throughput

0.479

High

97379

WFS1
Wolframin

1

2

High-throughput

0.479

High

97380

ACTB
Actin, cytoplasmic 1

1

2

High-throughput

0.479

High

97381

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

97382

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

97383

SNP25
Synaptosomal-associated protein 25

1

1

High-throughput

0.479

High

97384

RAB10
Ras-related protein Rab-10

1

7

High-throughput

0.479

High

97385

RAB8B
Ras-related protein Rab-8B

1

7

High-throughput

0.479

High

97387

RAP2B
Ras-related protein Rap-2b

1

6

High-throughput

0.479

High

97388

STX1B
Syntaxin-1B

1

7

High-throughput

0.479

High

97390

RAB3C
Ras-related protein Rab-3C

1

9

High-throughput

0.479

High

97391

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

4

High-throughput

0.479

High

97392

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

4

High-throughput

0.479

High

97393

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

4

High-throughput

0.479

High

97394

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

7

High-throughput

0.479

High

97395

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

5

High-throughput

0.479

High

97396

RAB3A
Ras-related protein Rab-3A

1

9

High-throughput

0.479

High

97397

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

97401

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

8

High-throughput

0.479

High

97403

ACTG
Actin, cytoplasmic 2

1

2

High-throughput

0.479

High

97406

PLXA1
Plexin-A1

1

2

High-throughput

0.479

High

97407

VAMP7
Vesicle-associated membrane protein 7

1

1

High-throughput

0.479

High

97408

AT8A1
Phospholipid-transporting ATPase IA

1

1

High-throughput

0.479

High

97410

ARF1
ADP-ribosylation factor 1

1

4

High-throughput

0.479

High

97412

NPTN
Neuroplastin

1

2

High-throughput

0.479

High

97413

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

1

3

High-throughput

0.479

High

97414

CXAR
Coxsackievirus and adenovirus receptor homolog

1

4

High-throughput

0.479

High

97415

SCN1B
Sodium channel regulatory subunit beta-1

1

5

High-throughput

0.479

High

97417

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

97418

CTNB1
Catenin beta-1

1

2

High-throughput

0.479

High

97420

GRM2
Metabotropic glutamate receptor 2

1

3

High-throughput

0.479

High

97421

VGLU1
Vesicular glutamate transporter 1

1

1

High-throughput

0.479

High

97422

MYCT
Proton myo-inositol cotransporter

1

1

High-throughput

0.479

High

97427

ICAM5
Intercellular adhesion molecule 5

1

5

High-throughput

0.479

High

97430

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

3

High-throughput

0.479

High

97431

SYPH
Synaptophysin

1

2

High-throughput

0.479

High

97432

HECAM
Hepatic and glial cell adhesion molecule

1

4

High-throughput

0.479

High

97433

GRM7
Metabotropic glutamate receptor 7

1

3

High-throughput

0.479

High

97434

CLH1
Clathrin heavy chain 1

1

1

High-throughput

0.479

High

97435

DPP10
Inactive dipeptidyl peptidase 10

1

1

High-throughput

0.479

High

97436

PRRT3
Proline-rich transmembrane protein 3

1

3

High-throughput

0.479

High

97437

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

5

High-throughput

0.479

High

97438

AT1A2
Sodium/potassium-transporting ATPase subunit alpha-2

1

5

High-throughput

0.479

High

97444

DLG1
Disks large homolog 1

1

4

High-throughput

0.479

High

97445

Q8BG33
Neurotrimin

1

1

High-throughput

0.479

High

97449

S6A17
Sodium-dependent neutral amino acid transporter SLC6A17

1

1

High-throughput

0.479

High

97453

TENR
Tenascin-R

1

6

High-throughput

0.479

High

97456

ABI1
Abl interactor 1

1

13

High-throughput

0.479

High

97457

CACB2
Voltage-dependent L-type calcium channel subunit beta-2

1

2

High-throughput

0.479

High

97458

SEPT8
Septin-8

1

9

High-throughput

0.479

High

97459

CACB4
Voltage-dependent L-type calcium channel subunit beta-4

1

2

High-throughput

0.479

High

97460

SNG3
Synaptogyrin-3

1

2

High-throughput

0.479

High

97461

CACB1
Voltage-dependent L-type calcium channel subunit beta-1

1

2

High-throughput

0.479

High

97463

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

5

High-throughput

0.479

High

97466

S12A5
Solute carrier family 12 member 5

1

4

High-throughput

0.479

High

97473

SYT12
Synaptotagmin-12

1

4

High-throughput

0.479

High

97477

PLPP3
Phospholipid phosphatase 3

1

1

High-throughput

0.479

High

97485

RAB5A
Ras-related protein Rab-5A

1

5

High-throughput

0.479

High

97498

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.479

High

97505

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

8

High-throughput

0.479

High

97514

AGK
Acylglycerol kinase, mitochondrial

1

1

High-throughput

0.479

High

97516

SV2A
Synaptic vesicle glycoprotein 2A

1

1

High-throughput

0.479

High

97518

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

97521

GRM3
Metabotropic glutamate receptor 3

1

3

High-throughput

0.479

High

97522

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

5

High-throughput

0.479

High

97524

ADA22
Disintegrin and metalloproteinase domain-containing protein 22

1

4

High-throughput

0.479

High

97525

ADA23
Disintegrin and metalloproteinase domain-containing protein 23

1

4

High-throughput

0.479

High

97530

DPP6
A-type potassium channel modulatory protein DPP6

1

1

High-throughput

0.479

High

97531

SEPT5
Septin-5

1

9

High-throughput

0.479

High

97337

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.458

High

97339

S4A4
Electrogenic sodium bicarbonate cotransporter 1

1

0

High-throughput

0.458

High

97346

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.458

High

97349

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

High-throughput

0.458

High

97364

GTR3
Solute carrier family 2, facilitated glucose transporter member 3

1

0

High-throughput

0.458

High

97375

VA0D1
V-type proton ATPase subunit d 1

1

0

High-throughput

0.458

High

97376

LIPS
Hormone-sensitive lipase

1

0

High-throughput

0.458

High

97389

KCAB2
Voltage-gated potassium channel subunit beta-2

1

0

High-throughput

0.458

High

97400

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.458

High

97402

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

0

High-throughput

0.458

High

97411

CPLX2
Complexin-2

1

0

High-throughput

0.458

High

97439

CSPG5
Chondroitin sulfate proteoglycan 5

1

0

High-throughput

0.458

High

97442

AGRL1
Adhesion G protein-coupled receptor L1

1

0

High-throughput

0.458

High

97452

CTL2
Choline transporter-like protein 2

1

0

High-throughput

0.458

High

97455

NRX3B
Neurexin-3-beta

1

0

High-throughput

0.458

High

97462

REEP2
Receptor expression-enhancing protein 2

1

0

High-throughput

0.458

High

97465

CCG8
Voltage-dependent calcium channel gamma-8 subunit

1

0

High-throughput

0.458

High

97471

Q91XH6
Vesicle transport through interaction with t-SNAREs homolog 1B

1

0

High-throughput

0.458

High

97474

BRNP1
BMP/retinoic acid-inducible neural-specific protein 1

1

0

High-throughput

0.458

High

97476

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.458

High

97492

SNAG
Gamma-soluble NSF attachment protein

1

0

High-throughput

0.458

High

97503

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.458

High

97515

PRAF2
PRA1 family protein 2

1

0

High-throughput

0.458

High

97517

NSMA2
Sphingomyelin phosphodiesterase 3

1

0

High-throughput

0.458

High

97527

GNAS3
Neuroendocrine secretory protein 55

1

0

High-throughput

0.458

High

97529

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.458

High

73055

B1AWE1
Clathrin light chain

1

2

High-throughput

0.437

High

97329

NCAM2
Neural cell adhesion molecule 2

1

3

High-throughput

0.437

High

97331

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.437

High

97341

NU4M
NADH-ubiquinone oxidoreductase chain 4

1

1

High-throughput

0.437

High

97342

TBA1B
Tubulin alpha-1B chain

1

5

High-throughput

0.437

High

97345

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

5

High-throughput

0.437

High

97361

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

4

High-throughput

0.437

High

97365

RAB18
Ras-related protein Rab-18

1

8

High-throughput

0.437

High

97386

ARF3
ADP-ribosylation factor 3

1

4

High-throughput

0.437

High

97404

TBA4A
Tubulin alpha-4A chain

1

4

High-throughput

0.437

High

97405

TBB4B
Tubulin beta-4B chain

1

4

High-throughput

0.437

High

97416

TBB5
Tubulin beta-5 chain

1

4

High-throughput

0.437

High

97419

ATP5I
ATP synthase F(0) complex subunit e, mitochondrial

1

1

High-throughput

0.437

High

97424

SCN2B
Sodium channel regulatory subunit beta-2

1

8

High-throughput

0.437

High

97425

PRAG1
Inactive tyrosine-protein kinase PRAG1

1

2

High-throughput

0.437

High

97426

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

3

High-throughput

0.437

High

97428

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

3

High-throughput

0.437

High

97429

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

3

High-throughput

0.437

High

97441

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

1

High-throughput

0.437

High

97446

Q8BH40
Syntaxin-7

1

6

High-throughput

0.437

High

97447

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

1

High-throughput

0.437

High

97448

ATLA1
Atlastin-1

1

1

High-throughput

0.437

High

97450

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

1

High-throughput

0.437

High

97451

AOFB
Amine oxidase [flavin-containing] B

1

2

High-throughput

0.437

High

97464

S25A3
Solute carrier family 25 member 3

1

1

High-throughput

0.437

High

97467

SFXN3
Sideroflexin-3

1

1

High-throughput

0.437

High

97475

SFXN5
Sideroflexin-5

1

1

High-throughput

0.437

High

97487

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

1

High-throughput

0.437

High

97493

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

1

1

High-throughput

0.437

High

97494

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

1

High-throughput

0.437

High

97495

BCS1
Mitochondrial chaperone BCS1

1

5

High-throughput

0.437

High

97497

RAB1B
Ras-related protein Rab-1B

1

5

High-throughput

0.437

High

97499

TBB4A
Tubulin beta-4A chain

1

4

High-throughput

0.437

High

97500

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

1

High-throughput

0.437

High

97501

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

1

High-throughput

0.437

High

97502

TMX2
Thioredoxin-related transmembrane protein 2

1

2

High-throughput

0.437

High

97504

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

2

High-throughput

0.437

High

97509

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

1

High-throughput

0.437

High

97511

STX12
Syntaxin-12

1

6

High-throughput

0.437

High

97512

TBB3
Tubulin beta-3 chain

1

4

High-throughput

0.437

High

97520

Q9MD82
NADH-ubiquinone oxidoreductase chain 5

1

1

High-throughput

0.437

High

97526

AT1A4
Sodium/potassium-transporting ATPase subunit alpha-4

1

5

High-throughput

0.437

High

97326

G5E814
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

1

0

High-throughput

0.249

Low

97327

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

1

0

High-throughput

0.249

Low

97334

NDUA1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1

1

0

High-throughput

0.249

Low

97340

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.249

Low

97348

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.249

Low

97355

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.249

Low

97370

CX6A1
Cytochrome c oxidase subunit 6A1, mitochondrial

1

0

High-throughput

0.249

Low

97377

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

1

0

High-throughput

0.249

Low

97398

MPC1
Mitochondrial pyruvate carrier 1

1

0

High-throughput

0.249

Low

97409

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.249

Low

97440

ATPMK
ATP synthase F(0) complex subunit k, mitochondrial

1

0

High-throughput

0.249

Low

97443

MFN2
Mitofusin-2

1

0

High-throughput

0.249

Low

97454

ENDD1
Endonuclease domain-containing 1 protein

1

0

High-throughput

0.249

Low

97468

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

0

High-throughput

0.249

Low

97469

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

0

High-throughput

0.249

Low

97470

CISD1
CDGSH iron-sulfur domain-containing protein 1

1

0

High-throughput

0.249

Low

97472

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.249

Low

97478

GLO2
Hydroxyacylglutathione hydrolase, mitochondrial

1

0

High-throughput

0.249

Low

97479

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

0

High-throughput

0.249

Low

97480

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.249

Low

97481

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

0

High-throughput

0.249

Low

97482

ATP5L
ATP synthase F(0) complex subunit g, mitochondrial

1

0

High-throughput

0.249

Low

97483

QCR8
Cytochrome b-c1 complex subunit 8

1

0

High-throughput

0.249

Low

97484

NDUB4
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

1

0

High-throughput

0.249

Low

97486

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

1

0

High-throughput

0.249

Low

97488

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

0

High-throughput

0.249

Low

97489

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

1

0

High-throughput

0.249

Low

97490

TMM33
Transmembrane protein 33

1

0

High-throughput

0.249

Low

97491

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

97496

ARM10
Armadillo repeat-containing protein 10

1

0

High-throughput

0.249

Low

97506

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.249

Low

97507

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

High-throughput

0.249

Low

97508

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

1

0

High-throughput

0.249

Low

97510

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

0

High-throughput

0.249

Low

97513

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.249

Low

97519

Q9MD68
Cytochrome c oxidase subunit 1

1

0

High-throughput

0.249

Low

97523

GUAD
Guanine deaminase

1

0

High-throughput

0.249

Low

97528

TWF2
Twinfilin-2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025