Protein: ALDH2
Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDHI)

Gene: ALDH2
Organism: Homo sapiens
Interactions: 107
UniProt ID: P05091

Gene Ontology (top 5):
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
GO:0004030 - aldehyde dehydrogenase [NAD(P)+] activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005975 - carbohydrate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

296356

AL1A2
Retinal dehydrogenase 2

3

13

High-throughput

0.861

High

396457

MMSA
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

3

14

High-throughput

0.861

High

334342

AL1A1
Aldehyde dehydrogenase 1A1

1

13

High-throughput

0.698

High

396444

AL1B1
Aldehyde dehydrogenase X, mitochondrial

1

13

High-throughput

0.691

High

361723

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

3

2

High-throughput

0.667

High

361807

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

3

2

High-throughput

0.667

High

361964

FIBG
Fibrinogen gamma chain

3

2

High-throughput

0.667

High

396434

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

13

Small-scale

0.647

High

344146

A1AT
Alpha-1-antitrypsin

3

0

High-throughput

0.638

High

361298

APOA1
Apolipoprotein A-I

3

0

High-throughput

0.638

High

364506

TRFE
Serotransferrin

3

0

High-throughput

0.638

High

396438

TAU
Microtubule-associated protein tau

2

5

High-throughput

0.628

High

396505

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

2

7

Small-scale

0.611

High

396480

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

2

High-throughput

0.611

High

396446

SPB5
Serpin B5

3

1

High-throughput

0.609

High

396439

CH60
60 kDa heat shock protein, mitochondrial

2

4

Small-scale

0.586

High

226248

PRKN
E3 ubiquitin-protein ligase parkin

2

9

High-throughput

0.584

High

396474

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

2

High-throughput

0.584

High

353836

IGHG3
Immunoglobulin heavy constant gamma 3

2

4

High-throughput

0.552

High

353869

IGHG4
Immunoglobulin heavy constant gamma 4

2

6

High-throughput

0.552

High

396465

CUL3
Cullin-3

1

3

High-throughput

0.536

High

396470

ICT1
Large ribosomal subunit protein mL62

1

2

High-throughput

0.536

High

396481

S35F6
Solute carrier family 35 member F6

1

0

High-throughput

0.518

High

393907

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

396469

DPYL1
Dihydropyrimidinase-related protein 1

1

3

High-throughput

0.494

High

121429

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

1

High-throughput

0.489

High

201173

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

High-throughput

0.489

High

396468

PKP1
Plakophilin-1

1

1

High-throughput

0.489

High

396472

MYLK
Myosin light chain kinase, smooth muscle

1

1

High-throughput

0.489

High

396496

KPCD2
Serine/threonine-protein kinase D2

1

1

High-throughput

0.489

High

262673

CISY
Citrate synthase, mitochondrial

1

1

High-throughput

0.479

High

264811

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.479

High

373503

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

396437

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

4

High-throughput

0.479

High

396448

MDHM
Malate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

396451

EFTU
Elongation factor Tu, mitochondrial

1

3

High-throughput

0.479

High

396452

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

396459

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

2

High-throughput

0.479

High

396460

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.479

High

396471

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.479

High

396478

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.479

High

396489

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

396493

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.479

High

396501

MTG2
Mitochondrial ribosome-associated GTPase 2

1

5

High-throughput

0.479

High

396504

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

1

High-throughput

0.479

High

396506

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

2

High-throughput

0.479

High

396440

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.470

High

396473

HSPB2
Heat shock protein beta-2

1

1

High-throughput

0.464

High

396453

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.460

High

396456

CH10
10 kDa heat shock protein, mitochondrial

1

0

Small-scale

0.460

High

59085

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

327333

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

396442

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

396449

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

396458

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

396461

TADBP
TAR DNA-binding protein 43

1

0

Small-scale

0.458

High

396467

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

396485

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.458

High

396486

MCUR1
Mitochondrial calcium uniporter regulator 1

1

0

High-throughput

0.458

High

396487

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

396492

TR61B
tRNA

1

0

High-throughput

0.458

High

396495

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

396499

MTRFR
Mitochondrial translation release factor in rescue

1

0

High-throughput

0.458

High

396503

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

396509

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

174543

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.457

High

353487

IGKC
Immunoglobulin kappa constant

1

3

High-throughput

0.445

High

353611

IGHG1
Immunoglobulin heavy constant gamma 1

1

6

High-throughput

0.445

High

354025

IGHA1
Immunoglobulin heavy constant alpha 1

1

6

High-throughput

0.445

High

396475

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

396514

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

7

High-throughput

0.445

High

396447

RL13A
Large ribosomal subunit protein uL13

1

1

High-throughput

0.439

High

396441

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

359564

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.437

High

384085

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

396443

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

396445

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

396450

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.437

High

396464

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.437

High

396466

CUL4A
Cullin-4A

1

3

High-throughput

0.437

High

396477

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.437

High

396479

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

396490

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.437

High

396491

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.437

High

396494

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.437

High

396500

Q9H4D1
Protein kinase

1

1

High-throughput

0.437

High

396502

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

396510

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.437

High

396512

FBW1A
F-box/WD repeat-containing protein 1A

1

3

Small-scale

0.437

High

396513

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.437

High

396435

JUN
Transcription factor Jun

1

2

High-throughput

0.407

High

396436

PRGR
Progesterone receptor

1

1

Small-scale

0.407

High

396454

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

396476

CP135
Centrosomal protein of 135 kDa

1

2

High-throughput

0.407

High

396498

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

3

High-throughput

0.407

High

396508

CALL5
Calmodulin-like protein 5

3

0

High-throughput

0.347

High

396463

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High

396488

IGS21
Immunoglobulin superfamily member 21

1

0

High-throughput

0.282

High

396511

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

396484

NEK7
Serine/threonine-protein kinase Nek7

1

0

High-throughput

0.279

Low

396497

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

0

High-throughput

0.279

Low

396482

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

396507

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

396462

CENPR
Centromere protein R

1

0

High-throughput

0.238

Low

396483

DEN10
DENN domain-containing protein 10

1

0

High-throughput

0.238

Low

396455

SMS
Somatostatin

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024