Protein: E41L2
Band 4.1-like protein 2 (Erythrocyte membrane protein band 4.1-like 2) (Generally expressed protein 4.1) (4.1G)

Gene: E41L2, EPB41L2
Organism: Homo sapiens
Interactions: 206
UniProt ID: O43491

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005198 - structural molecule activity
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

204760

E41L3
Band 4.1-like protein 3

4

16

High-throughput

0.903

High

204589

RASK
GTPase KRas

4

20

High-throughput

0.873

High

204738

E41L1
Band 4.1-like protein 1

2

16

High-throughput

0.811

High

204587

RASN
GTPase NRas

2

20

High-throughput

0.754

High

204643

1433G
14-3-3 protein gamma

5

20

High-throughput

0.725

High

204636

ICLN
Methylosome subunit pICln

3

6

High-throughput

0.675

High

204584

DDAH2
Putative hydrolase DDAH2

3

3

High-throughput

0.667

High

204648

1433Z
14-3-3 protein zeta/delta

3

20

High-throughput

0.658

High

165602

SET1A
Histone-lysine N-methyltransferase SETD1A

2

9

High-throughput

0.628

High

204582

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

2

1

High-throughput

0.628

High

204601

POTEI
POTE ankyrin domain family member I

2

4

High-throughput

0.628

High

204627

AF9
Protein AF-9

2

11

High-throughput

0.628

High

204634

CLK2
Dual specificity protein kinase CLK2

2

5

High-throughput

0.628

High

204651

ENL
Protein ENL

2

12

High-throughput

0.628

High

204661

PPIG
Peptidyl-prolyl cis-trans isomerase G

2

2

High-throughput

0.628

High

204671

RNPS1
RNA-binding protein with serine-rich domain 1

2

8

High-throughput

0.628

High

204685

WDR59
GATOR2 complex protein WDR59

2

3

High-throughput

0.628

High

204697

KIBRA
Protein KIBRA

2

20

High-throughput

0.628

High

204735

PININ
Pinin

2

4

High-throughput

0.628

High

204743

CWC22
Pre-mRNA-splicing factor CWC22 homolog

2

7

High-throughput

0.628

High

204755

SRP68
Signal recognition particle subunit SRP68

2

1

High-throughput

0.628

High

204757

ACINU
Apoptotic chromatin condensation inducer in the nucleus

2

11

High-throughput

0.628

High

204759

SRRM2
Serine/arginine repetitive matrix protein 2

2

16

High-throughput

0.628

High

204614

1433T
14-3-3 protein theta

2

20

High-throughput

0.628

High

204620

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.621

High

204667

NUMA1
Nuclear mitotic apparatus protein 1

2

11

Small-scale

0.619

High

204583

DIRA3
GTP-binding protein Di-Ras3

1

11

High-throughput

0.618

High

204585

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.618

High

204588

RASH
GTPase HRas

1

20

High-throughput

0.618

High

204599

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

204618

UFO
Tyrosine-protein kinase receptor UFO

1

20

Small-scale

0.618

High

204641

RAB2A
Ras-related protein Rab-2A

1

8

High-throughput

0.618

High

204646

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

204670

RAB35
Ras-related protein Rab-35

1

13

High-throughput

0.618

High

204598

A4
Amyloid-beta precursor protein

2

6

High-throughput

0.602

High

204571

PRKN
E3 ubiquitin-protein ligase parkin

2

8

High-throughput

0.584

High

204630

YAP1
Transcriptional coactivator YAP1

2

20

Small-scale

0.584

High

204645

ARF6
ADP-ribosylation factor 6

2

7

High-throughput

0.584

High

119889

AP3B1
AP-3 complex subunit beta-1

2

5

High-throughput

0.574

High

204726

CP2S1
Cytochrome P450 2S1

2

2

High-throughput

0.574

High

204756

GPTC8
G patch domain-containing protein 8

2

12

High-throughput

0.574

High

204590

ESR1
Estrogen receptor

2

18

High-throughput

0.571

High

204603

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

1

High-throughput

0.571

High

204659

GRM1
Metabotropic glutamate receptor 1

1

1

Small-scale

0.561

High

204644

1433E
14-3-3 protein epsilon

1

8

High-throughput

0.554

High

204653

1433F
14-3-3 protein eta

1

20

High-throughput

0.554

High

204626

GRIA1
Glutamate receptor 1

1

12

Small-scale

0.552

High

204596

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.541

High

61961

FA83G
Protein FAM83G

1

1

High-throughput

0.536

High

158255

LIN7A
Protein lin-7 homolog A

1

12

High-throughput

0.536

High

204574

CCNT1
Cyclin-T1

1

2

High-throughput

0.536

High

204576

SRS10
Serine/arginine-rich splicing factor 10

1

2

High-throughput

0.536

High

204609

CSK22
Casein kinase II subunit alpha'

1

8

High-throughput

0.536

High

204629

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.536

High

204632

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.536

High

204649

SRPK2
SRSF protein kinase 2

1

16

High-throughput

0.536

High

204693

PIM3
Serine/threonine-protein kinase pim-3

1

11

High-throughput

0.536

High

204698

KT222
Keratin-like protein KRT222

1

6

High-throughput

0.536

High

204701

NKAP
NF-kappa-B-activating protein

1

3

High-throughput

0.536

High

204702

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

1

High-throughput

0.536

High

204704

CAMKV
CaM kinase-like vesicle-associated protein

1

6

High-throughput

0.536

High

204711

HASP
Serine/threonine-protein kinase haspin

1

1

High-throughput

0.536

High

204715

FAN
Protein FAN

1

4

High-throughput

0.536

High

204761

M3K2
Mitogen-activated protein kinase kinase kinase 2

1

2

High-throughput

0.536

High

204741

WDR76
WD repeat-containing protein 76

2

3

High-throughput

0.533

High

204613

FKBP2
Peptidyl-prolyl cis-trans isomerase FKBP2

1

1

Small-scale

0.523

High

204569

PRC1
Protein regulator of cytokinesis 1

1

4

High-throughput

0.515

High

204579

DDAH1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

1

3

High-throughput

0.515

High

204606

FCGR1
High affinity immunoglobulin gamma Fc receptor I

1

7

Small-scale

0.515

High

204621

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

204719

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

7

High-throughput

0.515

High

204577

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.513

High

204612

PAX6
Paired box protein Pax-6

1

0

High-throughput

0.513

High

204640

MLF1
Myeloid leukemia factor 1

1

0

High-throughput

0.513

High

204681

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

High-throughput

0.513

High

204666

ARI5B
AT-rich interactive domain-containing protein 5B

1

0

High-throughput

0.493

High

204683

CXB7
Gap junction beta-7 protein

1

10

High-throughput

0.489

High

204694

ZCH18
Zinc finger CCCH domain-containing protein 18

1

14

High-throughput

0.489

High

204709

TBCK
TBC domain-containing protein kinase-like protein

1

12

High-throughput

0.489

High

204721

CERS2
Ceramide synthase 2

1

2

High-throughput

0.489

High

204722

KLH15
Kelch-like protein 15

1

3

High-throughput

0.489

High

204731

NUAK2
NUAK family SNF1-like kinase 2

1

8

High-throughput

0.489

High

204747

KLC4
Kinesin light chain 4

1

2

High-throughput

0.489

High

204600

ATX1L
Ataxin-1-like

1

1

High-throughput

0.481

High

119028

LEG9
Galectin-9

1

4

High-throughput

0.479

High

178312

STX7
Syntaxin-7

1

7

High-throughput

0.479

High

204570

STX6
Syntaxin-6

1

3

High-throughput

0.479

High

204572

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

10

High-throughput

0.479

High

204573

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

204575

PR40A
Pre-mRNA-processing factor 40 homolog A

1

17

High-throughput

0.479

High

204578

FLOT1
Flotillin-1

1

9

High-throughput

0.479

High

204586

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.479

High

204591

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

15

High-throughput

0.479

High

204593

GCR
Glucocorticoid receptor

1

17

High-throughput

0.479

High

204595

P53
Cellular tumor antigen p53

1

5

High-throughput

0.479

High

204597

H2A1B
Histone H2A type 1-B/E

1

3

High-throughput

0.479

High

204604

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.479

High

204605

LAMP1
Lysosome-associated membrane glycoprotein 1

1

7

High-throughput

0.479

High

204607

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

204608

CXA1
Gap junction alpha-1 protein

1

10

High-throughput

0.479

High

204611

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.479

High

204615

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

204616

PML
Protein PML

1

9

High-throughput

0.479

High

204617

MARCS
Myristoylated alanine-rich C-kinase substrate

1

10

High-throughput

0.479

High

204619

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

1

High-throughput

0.479

High

204622

STIP1
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.479

High

204623

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

204624

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

6

High-throughput

0.479

High

204625

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

204628

MUC18
Cell surface glycoprotein MUC18

1

12

High-throughput

0.479

High

204631

KC1D
Casein kinase I isoform delta

1

2

High-throughput

0.479

High

204633

RBM25
RNA-binding protein 25

1

13

High-throughput

0.479

High

204638

MFAP1
Microfibrillar-associated protein 1

1

1

High-throughput

0.479

High

204639

ARL4C
ADP-ribosylation factor-like protein 4C

1

20

High-throughput

0.479

High

204642

ABCE1
ATP-binding cassette sub-family E member 1

1

4

High-throughput

0.479

High

204652

CAV1
Caveolin-1

1

7

High-throughput

0.479

High

204654

UBE3A
Ubiquitin-protein ligase E3A

1

11

High-throughput

0.479

High

204657

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

12

High-throughput

0.479

High

204658

RFA4
Replication protein A 30 kDa subunit

1

7

High-throughput

0.479

High

204660

TIF1B
Transcription intermediary factor 1-beta

1

8

High-throughput

0.479

High

204662

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

204663

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

2

High-throughput

0.479

High

204664

SRC8
Src substrate cortactin

1

10

High-throughput

0.479

High

204665

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

7

High-throughput

0.479

High

204668

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

204669

KIF14
Kinesin-like protein KIF14

1

11

High-throughput

0.479

High

204672

OCLN
Occludin

1

10

High-throughput

0.479

High

204673

AR13B
ADP-ribosylation factor-like protein 13B

1

17

High-throughput

0.479

High

204674

MIDN
Midnolin

1

4

High-throughput

0.479

High

204677

RN123
E3 ubiquitin-protein ligase RNF123

1

7

High-throughput

0.479

High

204679

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

204682

TAF2
Transcription initiation factor TFIID subunit 2

1

2

High-throughput

0.479

High

204684

RHDF2
Inactive rhomboid protein 2

1

5

High-throughput

0.479

High

204686

RICTR
Rapamycin-insensitive companion of mTOR

1

5

High-throughput

0.479

High

204687

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

204692

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

204695

TAXB1
Tax1-binding protein 1

1

11

High-throughput

0.479

High

204700

ARL14
ADP-ribosylation factor-like protein 14

1

13

High-throughput

0.479

High

204703

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

2

High-throughput

0.479

High

204705

RB15B
Putative RNA-binding protein 15B

1

3

High-throughput

0.479

High

204712

ATX2L
Ataxin-2-like protein

1

6

High-throughput

0.479

High

204713

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

6

High-throughput

0.479

High

204714

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

204716

ESR2
Estrogen receptor beta

1

17

High-throughput

0.479

High

204718

CK052
Uncharacterized protein C11orf52

1

9

High-throughput

0.479

High

204720

SPDLY
Protein Spindly

1

7

High-throughput

0.479

High

204723

FMNL2
Formin-like protein 2

1

5

High-throughput

0.479

High

204725

CIC
Protein capicua homolog

1

15

High-throughput

0.479

High

204730

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

204733

NSRP1
Nuclear speckle splicing regulatory protein 1

1

3

High-throughput

0.479

High

204736

DNJC5
DnaJ homolog subfamily C member 5

1

7

High-throughput

0.479

High

204739

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

204740

BRD9
Bromodomain-containing protein 9

1

3

High-throughput

0.479

High

204744

ANLN
Anillin

1

6

High-throughput

0.479

High

204745

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

204748

DCA13
DDB1- and CUL4-associated factor 13

1

4

High-throughput

0.479

High

204749

ARL15
ADP-ribosylation factor-like protein 15

1

15

High-throughput

0.479

High

204750

DDX56
Probable ATP-dependent RNA helicase DDX56

1

3

High-throughput

0.479

High

204752

HDAC6
Histone deacetylase 6

1

6

High-throughput

0.479

High

204753

ABCF2
ATP-binding cassette sub-family F member 2

1

1

High-throughput

0.479

High

204754

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

204758

TRI33
E3 ubiquitin-protein ligase TRIM33

1

7

High-throughput

0.479

High

123141

CBX4
E3 SUMO-protein ligase CBX4

1

0

High-throughput

0.458

High

146002

CLD4
Claudin-4

1

0

Small-scale

0.458

High

204592

ALDOA
Fructose-bisphosphate aldolase A

1

0

High-throughput

0.458

High

204635

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

204637

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

204647

H4
Histone H4

1

0

High-throughput

0.458

High

204656

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.458

High

204691

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

204696

DDX42
ATP-dependent RNA helicase DDX42

1

0

High-throughput

0.458

High

204706

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

204707

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

204708

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

0

Small-scale

0.458

High

204724

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

0

High-throughput

0.458

High

204728

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

204732

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

204734

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

204742

MOV10
Helicase MOV-10

1

0

High-throughput

0.458

High

204746

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

204751

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

204655

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.457

High

204737

WNK1
Serine/threonine-protein kinase WNK1

1

9

High-throughput

0.457

High

204594

PRIO
Major prion protein

1

3

High-throughput

0.445

High

204602

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.445

High

204676

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

204680

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.445

High

100286

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

132377

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

4

High-throughput

0.437

High

204580

TOX4
TOX high mobility group box family member 4

1

2

High-throughput

0.437

High

204581

ZFPL1
Zinc finger protein-like 1

1

7

High-throughput

0.437

High

204610

HXA5
Homeobox protein Hox-A5

1

1

High-throughput

0.437

High

204650

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.437

High

204678

DCA15
DDB1- and CUL4-associated factor 15

1

2

High-throughput

0.437

High

204688

MOB3C
MOB kinase activator 3C

1

12

High-throughput

0.437

High

204690

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.437

High

204710

RHBL4
Rhomboid-related protein 4

1

5

High-throughput

0.437

High

204727

SEC62
Translocation protein SEC62

1

3

High-throughput

0.437

High

204729

MMTA2
Multiple myeloma tumor-associated protein 2

1

2

High-throughput

0.437

High

204762

ARL5A
ADP-ribosylation factor-like protein 5A

1

8

High-throughput

0.437

High

204699

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

204717

CSN5
COP9 signalosome complex subunit 5

1

0

Small-scale

0.426

High

73070

ZN736
Zinc finger protein 736

1

0

High-throughput

0.269

Low

204675

FA76B
Protein FAM76B

1

0

High-throughput

0.249

Low

204689

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.249

Low

204763

CCD61
Centrosomal protein CCDC61

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024