Protein: PIAS1
E3 SUMO-protein ligase PIAS1 (EC 2.3.2.27) (DEAD/H box-binding protein 1) (Protein inhibitor of activated STAT protein 1) (RING-type E3 ubiquitin transferase PIAS1)

Gene: PIAS1
Organism: Mus musculus
Interactions: 24
UniProt ID: O88907

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

313156

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

6

Small-scale

0.573

High

313151

TBP
TATA-box-binding protein

1

1

Small-scale

0.561

High

205246

AXIN1
Axin-1

1

2

Small-scale

0.552

High

313162

Q925T4
PLAGL2

1

6

Small-scale

0.527

High

237166

SAP18
Histone deacetylase complex subunit SAP18

1

0

Small-scale

0.486

High

313153

RN19A
E3 ubiquitin-protein ligase RNF19A

1

0

Small-scale

0.486

High

313157

ZN219
Zinc finger protein 219

1

0

Small-scale

0.486

High

313164

SUFU
Suppressor of fused homolog

1

0

Small-scale

0.486

High

63091

A5D6Q2
Nuclear receptor coactivator 3

1

7

Small-scale

0.481

High

109301

G5E8N3
Histone-lysine N-methyltransferase SETDB1

1

5

Small-scale

0.481

High

313148

P53
Cellular tumor antigen p53

1

10

Small-scale

0.481

High

313154

GLI2
Zinc finger protein GLI2

1

1

Small-scale

0.481

High

313159

Q8C253
Galectin

1

1

Small-scale

0.481

High

313161

TRI32
E3 ubiquitin-protein ligase TRIM32

1

13

Small-scale

0.481

High

313150

NECD
Necdin

1

3

Small-scale

0.479

High

313163

MAGD1
Melanoma-associated antigen D1

1

2

Small-scale

0.479

High

148553

NCOA3
Nuclear receptor coactivator 3

1

7

Small-scale

0.457

High

313147

SETB1
Histone-lysine N-methyltransferase SETDB1

1

5

Small-scale

0.457

High

313149

LEG3
Galectin-3

1

1

Small-scale

0.457

High

313152

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

1

Small-scale

0.457

High

313158

Q8BK32
Nuclear receptor co-repressor 1

1

1

Small-scale

0.439

High

313160

HECD2
Probable E3 ubiquitin-protein ligase HECTD2

1

6

Small-scale

0.437

High

313155

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.426

High

312751

LTOR3
Ragulator complex protein LAMTOR3

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025