Protein: H2A2A
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)

Gene: H2A2A, H2AC18
Organism: Homo sapiens
Interactions: 164
UniProt ID: Q6FI13

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0005634 - nucleus
GO:0030527 - structural constituent of chromatin
GO:0031492 - nucleosomal DNA binding
GO:0046982 - protein heterodimerization activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

918440

H2B1C
Histone H2B type 1-C/E/F/G/I

4

20

High-throughput

0.873

High

1151374

RING2
E3 ubiquitin-protein ligase RING2

3

20

Small-scale

0.840

High

917438

H4
Histone H4

3

13

High-throughput

0.827

High

420844

H2B1J
Histone H2B type 1-J

2

20

High-throughput

0.789

High

832523

MCM2
DNA replication licensing factor MCM2

2

20

High-throughput

0.789

High

996711

SSRP1
FACT complex subunit SSRP1

2

20

High-throughput

0.789

High

1151400

SP16H
FACT complex subunit SPT16

2

9

High-throughput

0.789

High

717932

BMI1
Polycomb complex protein BMI-1

2

20

Small-scale

0.768

High

1151376

H2B1N
Histone H2B type 1-N

2

20

High-throughput

0.757

High

241559

H2B1K
Histone H2B type 1-K

2

20

High-throughput

0.754

High

934877

H31
Histone H3.1

2

20

High-throughput

0.754

High

1086182

H31T
Histone H3.1t

2

20

High-throughput

0.754

High

1087194

H2B2E
Histone H2B type 2-E

2

20

Small-scale

0.754

High

1151349

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

20

Small-scale

0.691

High

1151350

H2A2B
Histone H2A type 2-B

1

14

High-throughput

0.691

High

1017148

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

4

Small-scale

0.665

High

1151403

U3KQK0
Histone H2B

1

20

High-throughput

0.665

High

475912

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

16

High-throughput

0.647

High

176209

PPM1G
Protein phosphatase 1G

2

11

High-throughput

0.628

High

1151371

IPO9
Importin-9

1

9

High-throughput

0.618

High

391748

H2A1B
Histone H2A type 1-B/E

1

15

High-throughput

0.618

High

470417

H2A1
Histone H2A type 1

1

15

High-throughput

0.618

High

594851

H2A1D
Histone H2A type 1-D

1

15

High-throughput

0.618

High

617952

H2B1O
Histone H2B type 1-O

1

20

High-throughput

0.618

High

707657

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.618

High

886132

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.618

High

924034

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

17

High-throughput

0.618

High

924322

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

16

High-throughput

0.618

High

1151344

H32
Histone H3.2

1

20

High-throughput

0.618

High

1151347

H2A3
Histone H2A type 3

1

14

High-throughput

0.618

High

1151355

H2B3B
Histone H2B type 3-B

1

20

High-throughput

0.618

High

1151365

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.618

High

1151377

H2B1L
Histone H2B type 1-L

1

20

High-throughput

0.618

High

564939

HMGA1
High mobility group protein HMG-I/HMG-Y

2

6

High-throughput

0.611

High

1151382

WDR76
WD repeat-containing protein 76

2

15

High-throughput

0.611

High

394926

A4
Amyloid-beta precursor protein

2

2

High-throughput

0.602

High

1151353

RN168
E3 ubiquitin-protein ligase RNF168

2

12

Small-scale

0.595

High

338555

EGFR
Epidermal growth factor receptor

2

2

Small-scale

0.584

High

489096

H14
Histone H1.4

2

20

High-throughput

0.584

High

408631

KPCB
Protein kinase C beta type

2

10

High-throughput

0.571

High

657839

ELK4
ETS domain-containing protein Elk-4

2

9

High-throughput

0.571

High

1151375

DNJC2
DnaJ homolog subfamily C member 2

1

7

Small-scale

0.561

High

179047

TNC18
Trinucleotide repeat-containing gene 18 protein

1

9

High-throughput

0.553

High

272879

KS6A4
Ribosomal protein S6 kinase alpha-4

1

8

High-throughput

0.536

High

299066

PHF14
PHD finger protein 14

1

8

High-throughput

0.536

High

440571

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.536

High

449745

HMGB1
High mobility group protein B1

1

20

High-throughput

0.536

High

557716

NCK1
SH2/SH3 adapter protein NCK1

1

3

High-throughput

0.536

High

708464

MCM4
DNA replication licensing factor MCM4

1

20

High-throughput

0.536

High

967041

XPC
DNA repair protein complementing XP-C cells

1

5

High-throughput

0.536

High

997767

RBBP4
Histone-binding protein RBBP4

1

9

High-throughput

0.536

High

1021673

MYO1E
Unconventional myosin-Ie

1

4

High-throughput

0.536

High

1061142

NUMA1
Nuclear mitotic apparatus protein 1

1

11

High-throughput

0.536

High

1110489

GON4L
GON-4-like protein

1

6

High-throughput

0.536

High

1151342

MMS22
Protein MMS22-like

1

4

High-throughput

0.536

High

1151351

APLF
Aprataxin and PNK-like factor

1

4

High-throughput

0.536

High

1151354

MIER1
Mesoderm induction early response protein 1

1

15

High-throughput

0.536

High

1151362

GEMI5
Gem-associated protein 5

1

9

High-throughput

0.536

High

1151378

COR1B
Coronin-1B

1

10

High-throughput

0.536

High

1151381

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

2

High-throughput

0.536

High

1151386

HM20A
High mobility group protein 20A

1

20

High-throughput

0.536

High

1151392

CFDP1
Craniofacial development protein 1

1

4

High-throughput

0.536

High

1151393

PARP2
Poly [ADP-ribose] polymerase 2

1

13

High-throughput

0.536

High

1151396

RUVB2
RuvB-like 2

1

9

High-throughput

0.536

High

1151402

EPN1
Epsin-1

1

3

High-throughput

0.536

High

1030294

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.515

High

154201

CHK1
Serine/threonine-protein kinase Chk1

1

0

High-throughput

0.513

High

1036418

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

0

High-throughput

0.513

High

1062957

MD2BP
MAD2L1-binding protein

1

0

High-throughput

0.513

High

1151346

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.513

High

1151397

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.513

High

245612

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

6

Small-scale

0.501

High

321318

IL33
Interleukin-33

1

1

Small-scale

0.501

High

455554

PARP1
Poly [ADP-ribose] polymerase 1

1

20

Small-scale

0.501

High

1138171

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

18

Small-scale

0.501

High

1151358

RN169
E3 ubiquitin-protein ligase RNF169

1

9

Small-scale

0.501

High

1151364

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

Small-scale

0.501

High

1151370

ANM6
Protein arginine N-methyltransferase 6

1

5

High-throughput

0.501

High

1151385

MSL2
E3 ubiquitin-protein ligase MSL2

1

1

Small-scale

0.501

High

1151399

NOC2L
Nucleolar complex protein 2 homolog

1

3

Small-scale

0.501

High

1151401

UBP16
Ubiquitin carboxyl-terminal hydrolase 16

1

14

Small-scale

0.501

High

157048

AIM2
Interferon-inducible protein AIM2

1

2

High-throughput

0.489

High

307536

EPN2
Epsin-2

1

2

High-throughput

0.489

High

324822

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

13

High-throughput

0.489

High

781557

CETN2
Centrin-2

1

6

High-throughput

0.489

High

851543

NEK4
Serine/threonine-protein kinase Nek4

1

15

High-throughput

0.489

High

948601

RT09
Small ribosomal subunit protein uS9m

1

4

High-throughput

0.489

High

1103044

ATG2A
Autophagy-related protein 2 homolog A

1

1

High-throughput

0.489

High

1151341

CP087
UPF0547 protein C16orf87

1

4

High-throughput

0.489

High

1151357

NECP1
Adaptin ear-binding coat-associated protein 1

1

1

High-throughput

0.489

High

1151363

TRI41
E3 ubiquitin-protein ligase TRIM41

1

3

High-throughput

0.489

High

1151369

TONSL
Tonsoku-like protein

1

13

High-throughput

0.489

High

1151373

FNBP1
Formin-binding protein 1

1

4

High-throughput

0.489

High

62086

EPAB2
Embryonic polyadenylate-binding protein 2

1

9

High-throughput

0.479

High

124229

TAF4
Transcription initiation factor TFIID subunit 4

1

7

High-throughput

0.479

High

213571

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

3

High-throughput

0.479

High

303297

HEXI1
Protein HEXIM1

1

12

High-throughput

0.479

High

398895

HMGN2
Non-histone chromosomal protein HMG-17

1

9

High-throughput

0.479

High

578452

RCC1
Regulator of chromosome condensation

1

5

High-throughput

0.479

High

596222

NEBU
Nebulin

1

6

High-throughput

0.479

High

610738

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

3

Small-scale

0.479

High

643357

HMGB2
High mobility group protein B2

1

20

High-throughput

0.479

High

708681

MCM5
DNA replication licensing factor MCM5

1

20

High-throughput

0.479

High

792998

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

6

High-throughput

0.479

High

800797

MK08
Mitogen-activated protein kinase 8

1

5

High-throughput

0.479

High

840732

DYN2
Dynamin-2

1

3

High-throughput

0.479

High

841774

CDK9
Cyclin-dependent kinase 9

1

9

High-throughput

0.479

High

905432

RRAS2
Ras-related protein R-Ras2

1

2

High-throughput

0.479

High

913578

RL7A
Large ribosomal subunit protein eL8

1

4

High-throughput

0.479

High

921298

RBX1
E3 ubiquitin-protein ligase RBX1

1

4

High-throughput

0.479

High

1038464

HDAC1
Histone deacetylase 1

1

13

Small-scale

0.479

High

1041798

CUL3
Cullin-3

1

14

High-throughput

0.479

High

1048105

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

20

Small-scale

0.479

High

1063449

SUZ12
Polycomb protein SUZ12

1

3

High-throughput

0.479

High

1067005

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.479

High

1067434

EEA1
Early endosome antigen 1

1

20

High-throughput

0.479

High

1116320

LARP7
La-related protein 7

1

20

High-throughput

0.479

High

1122689

ESCO2
N-acetyltransferase ESCO2

1

1

Small-scale

0.479

High

1148629

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

1151345

MEPCE
7SK snRNA methylphosphate capping enzyme

1

12

High-throughput

0.479

High

1151348

SLN11
Schlafen family member 11

1

6

High-throughput

0.479

High

1151352

SRRM1
Serine/arginine repetitive matrix protein 1

1

8

High-throughput

0.479

High

1151361

SMRC2
SWI/SNF complex subunit SMARCC2

1

13

High-throughput

0.479

High

1151366

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

1151367

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

10

High-throughput

0.479

High

1151368

AURKB
Aurora kinase B

1

10

Small-scale

0.479

High

1151380

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

17

High-throughput

0.479

High

1151395

RL26L
Ribosomal protein uL24-like

1

7

High-throughput

0.479

High

122825

MEN1
Menin

1

0

Small-scale

0.458

High

1048043

CYLC2
Cylicin-2

1

0

High-throughput

0.458

High

1151390

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

1151394

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

14

Small-scale

0.457

High

924639

GRB2
Growth factor receptor-bound protein 2

1

3

High-throughput

0.445

High

1032470

CTBP1
C-terminal-binding protein 1

1

3

High-throughput

0.445

High

1130186

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

1151383

LN28A
Protein lin-28 homolog A

1

20

High-throughput

0.445

High

148937

CTRO
Citron Rho-interacting kinase

1

11

High-throughput

0.437

High

255860

OBSL1
Obscurin-like protein 1

1

5

High-throughput

0.437

High

430980

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

4

High-throughput

0.437

High

610436

CBL
E3 ubiquitin-protein ligase CBL

1

10

High-throughput

0.437

High

618643

IF4B
Eukaryotic translation initiation factor 4B

1

9

High-throughput

0.437

High

807754

MAP1B
Microtubule-associated protein 1B

1

5

High-throughput

0.437

High

814804

RL29
Large ribosomal subunit protein eL29

1

1

High-throughput

0.437

High

824106

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

7

High-throughput

0.437

High

1061463

CUL7
Cullin-7

1

1

High-throughput

0.437

High

1063867

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.437

High

1136124

RC3H1
Roquin-1

1

3

High-throughput

0.437

High

1151343

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.437

High

1151360

NUP43
Nucleoporin Nup43

1

12

High-throughput

0.437

High

1151384

RC3H2
Roquin-2

1

12

High-throughput

0.437

High

1151388

ANLN
Anillin

1

3

High-throughput

0.437

High

1151391

DAPLE
Protein Daple

1

20

High-throughput

0.437

High

240048

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.407

High

1151372

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

1

High-throughput

0.407

High

1151356

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

0

High-throughput

0.279

Low

1151359

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.279

Low

1151387

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

0

High-throughput

0.279

Low

1151389

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

0

High-throughput

0.279

Low

1151398

EMC9
ER membrane protein complex subunit 9

1

0

High-throughput

0.279

Low

168260

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.249

Low

255161

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.249

Low

910700

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.249

Low

985675

CTSL2
CTD small phosphatase-like protein 2

1

0

Small-scale

0.249

Low

1151379

CNPY3
Protein canopy homolog 3

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024