HitPredict

Interactor 1: NCBP1 (O14253)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: cbc1

Interactor 2: NCBP2 (Q9P383)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)
Gene: cbc2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25989903
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MIF4G_like~RRM_1, MIF4G_like_2~RRM_1
Common GO terms	GO:0000339 - RNA cap binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0005846 - nuclear cap binding complex GO:0048471 - perinuclear region of cytoplasm and 1 others more... GO:0072686 - mitotic spindle
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 780 Sp			1 182
+	Sp
		145203 NCBP1_SCHPO (1-780): 0: 1077: 100.00		PAB2_SCHPO (2-105): 6.17e-14: 67.8: 27.89
+	Hs
		853870 NCBP1_HUMAN (12-689): 0: 834: 21.34		NCBP2_HUMAN (9-146): 1.12e-35: 123: 58.27
+	Hs
		998037 NCBP1_HUMAN (12-689): 0: 834: 21.34		PABP4_HUMAN (20-181): 4.81e-27: 108: 12.58
+	Hs
		516479 NCBP1_HUMAN (12-689): 0: 834: 21.34		PABP1_HUMAN (4-180): 1.54e-26: 106: 13.73
+	Hs
		998026 NCBP1_HUMAN (12-689): 0: 834: 21.34		ELAV2_HUMAN (22-137): 5.62e-22: 92.7: 17.80
+	Hs
		442102 NCBP1_HUMAN (12-689): 0: 834: 21.34		RU17_HUMAN (32-110): 4.51e-12: 65.1: 26.58
+	Dm
		1180175 NCBP1_DROME (11-689): 0: 717: 23.63		NCBP2_DROME (6-143): 9.68e-36: 123: 52.52
+	At
		1352340 NCBP1_ARATH (38-683): 0: 645: 22.03		NCBP2_ARATH (1-164): 8.77e-39: 134: 52.38
+	Sc
		710232 NCBP1_YEAST (11-643): 2.82e-109: 355: 21.81		NCBP2_YEAST (3-144): 1.69e-34: 122: 58.62
+	Sc
		376713 NCBP1_YEAST (11-643): 2.82e-109: 355: 21.81		PABP_YEAST (20-175): 8.31e-24: 99.3: 14.91