Protein: DZIP3
E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138)

Gene: DZIP3
Organism: Homo sapiens
Interactions: 175
UniProt ID: Q86Y13

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0003723 - RNA binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0019902 - phosphatase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1205115

UB2E2
Ubiquitin-conjugating enzyme E2 E2

4

20

High-throughput

0.885

High

849362

UB2D1
Ubiquitin-conjugating enzyme E2 D1

2

20

Small-scale

0.800

High

919775

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

20

Small-scale

0.800

High

1205096

DZIP3
E3 ubiquitin-protein ligase DZIP3

2

17

Small-scale

0.778

High

1205125

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

4

11

High-throughput

0.705

High

851839

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

High-throughput

0.698

High

895840

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

High-throughput

0.698

High

896485

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

High-throughput

0.698

High

908771

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.698

High

930285

UBC9
SUMO-conjugating enzyme UBC9

1

20

High-throughput

0.698

High

1033118

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

20

High-throughput

0.698

High

1079001

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

20

High-throughput

0.698

High

1138888

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.698

High

1174502

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

20

High-throughput

0.698

High

1205108

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

20

High-throughput

0.698

High

1205109

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

20

High-throughput

0.698

High

1205130

RNF38
E3 ubiquitin-protein ligase RNF38

1

10

High-throughput

0.698

High

1205159

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

High-throughput

0.698

High

868588

ATX1
Ataxin-1

3

2

Small-scale

0.676

High

855122

HNRPF
Heterogeneous nuclear ribonucleoprotein F

3

20

High-throughput

0.675

High

563632

ZNF24
Zinc finger protein 24

3

6

High-throughput

0.664

High

963544

TIAR
Nucleolysin TIAR

3

8

High-throughput

0.657

High

1205124

RBM4B
RNA-binding protein 4B

2

17

High-throughput

0.628

High

1205133

UBE2Z
Ubiquitin-conjugating enzyme E2 Z

1

20

High-throughput

0.625

High

1205134

AKTIP
AKT-interacting protein

1

20

High-throughput

0.625

High

1204045

CARM1
Histone-arginine methyltransferase CARM1

2

3

Small-scale

0.624

High

896331

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

20

High-throughput

0.621

High

1205144

RN181
E3 ubiquitin-protein ligase RNF181

1

8

High-throughput

0.618

High

1205160

RNF11
RING finger protein 11

1

13

Small-scale

0.618

High

314086

BAG4
BAG family molecular chaperone regulator 4

2

5

High-throughput

0.606

High

682879

HNRH1
Heterogeneous nuclear ribonucleoprotein H

2

20

High-throughput

0.606

High

941925

PITX1
Pituitary homeobox 1

2

3

High-throughput

0.606

High

1144563

TENS2
Tensin-2

2

7

High-throughput

0.606

High

1205102

ZCH10
Zinc finger CCHC domain-containing protein 10

3

1

High-throughput

0.606

High

387039

P53
Cellular tumor antigen p53

2

9

Small-scale

0.595

High

1205129

TOLIP
Toll-interacting protein

1

2

High-throughput

0.586

High

1038502

HDAC1
Histone deacetylase 1

2

14

Small-scale

0.584

High

1205110

PF21A
PHD finger protein 21A

2

9

Small-scale

0.584

High

1205111

FBX17
F-box only protein 17

2

0

High-throughput

0.580

High

1184436

ZN765
Zinc finger protein 765

1

1

High-throughput

0.573

High

622490

CCND1
G1/S-specific cyclin-D1

1

3

Small-scale

0.561

High

678945

HXC8
Homeobox protein Hox-C8

2

2

High-throughput

0.553

High

585003

RO52
E3 ubiquitin-protein ligase TRIM21

1

9

High-throughput

0.541

High

1035867

BIRC3
Baculoviral IAP repeat-containing protein 3

1

7

High-throughput

0.541

High

1036294

BIRC2
Baculoviral IAP repeat-containing protein 2

1

7

High-throughput

0.541

High

1108512

PCGF3
Polycomb group RING finger protein 3

1

9

High-throughput

0.541

High

71170

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

14

High-throughput

0.536

High

72144

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

20

High-throughput

0.528

High

391774

H2A1B
Histone H2A type 1-B/E

1

13

Small-scale

0.528

High

64722

RHG32
Rho GTPase-activating protein 32

1

6

High-throughput

0.523

High

1205116

CEP63
Centrosomal protein of 63 kDa

1

20

High-throughput

0.523

High

1205126

AP1M1
AP-1 complex subunit mu-1

1

2

High-throughput

0.523

High

1170430

UBR3
E3 ubiquitin-protein ligase UBR3

1

0

High-throughput

0.518

High

1205123

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.518

High

1205143

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.518

High

794030

MATR3
Matrin-3

1

11

High-throughput

0.515

High

1054159

BECN1
Beclin-1

1

0

High-throughput

0.513

High

1205161

GRIP1
Glutamate receptor-interacting protein 1

1

13

Small-scale

0.512

High

1205141

DAZ1
Deleted in azoospermia protein 1

1

20

Small-scale

0.508

High

906004

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

10

Small-scale

0.501

High

241178

TOM1
Target of Myb1 membrane trafficking protein

1

9

High-throughput

0.479

High

296064

MTA2
Metastasis-associated protein MTA2

1

5

Small-scale

0.479

High

431002

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

2

High-throughput

0.479

High

443630

VIME
Vimentin

1

20

Small-scale

0.479

High

538574

CCNB1
G2/mitotic-specific cyclin-B1

1

1

Small-scale

0.479

High

613513

SFPQ
Splicing factor, proline- and glutamine-rich

1

17

Small-scale

0.479

High

632800

TYY1
Transcriptional repressor protein YY1

1

5

Small-scale

0.479

High

668383

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

12

High-throughput

0.479

High

673601

MPIP3
M-phase inducer phosphatase 3

1

1

Small-scale

0.479

High

820967

PRC2A
Protein PRRC2A

1

17

High-throughput

0.479

High

902956

DCAF7
DDB1- and CUL4-associated factor 7

1

19

Small-scale

0.479

High

944311

PRKDC
DNA-dependent protein kinase catalytic subunit

1

7

Small-scale

0.479

High

950215

SMAD3
Mothers against decapentaplegic homolog 3

1

3

Small-scale

0.479

High

1029601

TIF1B
Transcription intermediary factor 1-beta

1

13

Small-scale

0.479

High

1031895

MTA1
Metastasis-associated protein MTA1

1

5

Small-scale

0.479

High

1041079

CUL1
Cullin-1

1

11

Small-scale

0.479

High

1043443

CUL4B
Cullin-4B

1

11

Small-scale

0.479

High

1045130

RUNX3
Runt-related transcription factor 3

1

1

Small-scale

0.479

High

1050130

GIT2
ARF GTPase-activating protein GIT2

1

11

High-throughput

0.479

High

1056686

PUM1
Pumilio homolog 1

1

3

High-throughput

0.479

High

1057306

SMC1A
Structural maintenance of chromosomes protein 1A

1

15

Small-scale

0.479

High

1059713

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

9

Small-scale

0.479

High

1069734

NONO
Non-POU domain-containing octamer-binding protein

1

20

Small-scale

0.479

High

1078725

SMAD1
Mothers against decapentaplegic homolog 1

1

3

Small-scale

0.479

High

1082265

DDB1
DNA damage-binding protein 1

1

3

Small-scale

0.479

High

1083301

RBBP7
Histone-binding protein RBBP7

1

19

Small-scale

0.479

High

1089523

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

10

High-throughput

0.479

High

1157565

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.479

High

1168776

MEX3B
RNA-binding protein MEX3B

1

1

High-throughput

0.479

High

1192320

YTHD3
YTH domain-containing family protein 3

1

11

High-throughput

0.479

High

1205097

P66A
Transcriptional repressor p66-alpha

1

2

Small-scale

0.479

High

1205098

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

18

High-throughput

0.479

High

1205099

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

4

High-throughput

0.479

High

1205101

LNX1
E3 ubiquitin-protein ligase LNX

1

13

Small-scale

0.479

High

1205104

GEMI5
Gem-associated protein 5

1

10

Small-scale

0.479

High

1205105

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

1205106

FUBP2
Far upstream element-binding protein 2

1

15

High-throughput

0.479

High

1205107

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

5

Small-scale

0.479

High

1205113

FUBP3
Far upstream element-binding protein 3

1

15

High-throughput

0.479

High

1205118

RBM14
RNA-binding protein 14

1

13

Small-scale

0.479

High

1205119

WRIP1
ATPase WRNIP1

1

7

High-throughput

0.479

High

1205120

SIN3A
Paired amphipathic helix protein Sin3a

1

2

Small-scale

0.479

High

1205121

CDC5L
Cell division cycle 5-like protein

1

2

Small-scale

0.479

High

1205122

ATX2
Ataxin-2

1

8

High-throughput

0.479

High

1205127

YTHD1
YTH domain-containing family protein 1

1

11

High-throughput

0.479

High

1205131

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

14

Small-scale

0.479

High

1205132

TDRD3
Tudor domain-containing protein 3

1

1

High-throughput

0.479

High

1205135

MOV10
Helicase MOV-10

1

3

High-throughput

0.479

High

1205136

NCK5L
Nck-associated protein 5-like

1

2

High-throughput

0.479

High

1205138

TUFT1
Tuftelin

1

1

High-throughput

0.479

High

1205142

BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A

1

12

Small-scale

0.479

High

1205146

LIMD1
LIM domain-containing protein 1

1

15

Small-scale

0.479

High

1205148

HERC5
E3 ISG15--protein ligase HERC5

1

13

Small-scale

0.479

High

1205149

RABX5
Rab5 GDP/GTP exchange factor

1

2

High-throughput

0.479

High

1205153

MYO6
Unconventional myosin-VI

1

18

High-throughput

0.479

High

1205156

RUVB2
RuvB-like 2

1

7

Small-scale

0.479

High

1205158

R3HD2
R3H domain-containing protein 2

1

6

High-throughput

0.479

High

1205162

YTHD2
YTH domain-containing family protein 2

1

12

High-throughput

0.479

High

1045452

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

20

High-throughput

0.470

High

122212

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.458

High

154209

CHK1
Serine/threonine-protein kinase Chk1

1

0

Small-scale

0.458

High

204376

MS18B
Protein Mis18-beta

1

0

High-throughput

0.458

High

471620

TFPT
TCF3 fusion partner

1

0

High-throughput

0.458

High

1205137

BRMS1
Breast cancer metastasis-suppressor 1

1

0

Small-scale

0.458

High

964364

RUNX1
Runt-related transcription factor 1

1

1

Small-scale

0.457

High

1205150

TNIK
TRAF2 and NCK-interacting protein kinase

1

18

High-throughput

0.457

High

1199972

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

9

High-throughput

0.445

High

124234

TAF4
Transcription initiation factor TFIID subunit 4

1

8

Small-scale

0.437

High

126147

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

8

High-throughput

0.437

High

155024

NDC80
Kinetochore protein NDC80 homolog

1

18

High-throughput

0.437

High

181538

CLOCK
Circadian locomoter output cycles protein kaput

1

8

High-throughput

0.437

High

232291

KDM1A
Lysine-specific histone demethylase 1A

1

4

High-throughput

0.437

High

261541

NCOR1
Nuclear receptor corepressor 1

1

14

Small-scale

0.437

High

414331

RB
Retinoblastoma-associated protein

1

1

Small-scale

0.437

High

438960

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

5

Small-scale

0.437

High

595292

LMNB1
Lamin-B1

1

17

Small-scale

0.437

High

658699

SMCA1
Probable global transcription activator SNF2L1

1

12

Small-scale

0.437

High

794275

MSH2
DNA mismatch repair protein Msh2

1

2

Small-scale

0.437

High

881217

CTBP2
C-terminal-binding protein 2

1

3

Small-scale

0.437

High

898150

MAX
Protein max

1

4

High-throughput

0.437

High

934285

CSK21
Casein kinase II subunit alpha

1

12

Small-scale

0.437

High

980804

TLE3
Transducin-like enhancer protein 3

1

16

Small-scale

0.437

High

997791

RBBP4
Histone-binding protein RBBP4

1

15

Small-scale

0.437

High

1032498

CTBP1
C-terminal-binding protein 1

1

3

Small-scale

0.437

High

1070136

RABE1
Rab GTPase-binding effector protein 1

1

16

High-throughput

0.437

High

1074796

TAF5
Transcription initiation factor TFIID subunit 5

1

10

Small-scale

0.437

High

1087235

H2B2E
Histone H2B type 2-E

1

12

Small-scale

0.437

High

1118315

GRAP1
GRIP1-associated protein 1

1

18

High-throughput

0.437

High

1121525

EIPR1
EARP and GARP complex-interacting protein 1

1

14

High-throughput

0.437

High

1122589

CCD93
Coiled-coil domain-containing protein 93

1

11

High-throughput

0.437

High

1155856

PHLB3
Pleckstrin homology-like domain family B member 3

1

16

High-throughput

0.437

High

1160249

PKN3
Serine/threonine-protein kinase N3

1

12

High-throughput

0.437

High

1173018

TM1L2
TOM1-like protein 2

1

9

High-throughput

0.437

High

1190365

HAUS6
HAUS augmin-like complex subunit 6

1

3

High-throughput

0.437

High

1205100

GOGA5
Golgin subfamily A member 5

1

19

High-throughput

0.437

High

1205103

CCHCR
Coiled-coil alpha-helical rod protein 1

1

16

High-throughput

0.437

High

1205117

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

1

High-throughput

0.437

High

1205128

NUF2
Kinetochore protein Nuf2

1

18

High-throughput

0.437

High

1205139

HM20A
High mobility group protein 20A

1

9

High-throughput

0.437

High

1205145

ZMYM2
Zinc finger MYM-type protein 2

1

1

High-throughput

0.437

High

1205151

RCOR1
REST corepressor 1

1

7

High-throughput

0.437

High

1205154

MAGD2
Melanoma-associated antigen D2

1

11

Small-scale

0.437

High

1205155

SMC3
Structural maintenance of chromosomes protein 3

1

8

Small-scale

0.437

High

1205157

RUVB1
RuvB-like 1

1

7

Small-scale

0.437

High

1205163

NS1BP
Influenza virus NS1A-binding protein

1

6

Small-scale

0.437

High

1205140

MED4
Mediator of RNA polymerase II transcription subunit 4

2

0

High-throughput

0.328

High

1158416

T2H2L
General transcription factor IIH subunit 2-like protein

1

0

High-throughput

0.299

High

81736

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

High-throughput

0.249

Low

317470

YETS4
YEATS domain-containing protein 4

1

0

High-throughput

0.249

Low

1137627

VPS53
Vacuolar protein sorting-associated protein 53 homolog

1

0

High-throughput

0.249

Low

1205112

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.249

Low

1205114

VPS50
Syndetin

1

0

High-throughput

0.249

Low

1205147

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.249

Low

1205152

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024