Protein: PDE10
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17)

Gene: PDE10, Pde10a
Organism: Mus musculus
Interactions: 10
UniProt ID: Q8CA95

Gene Ontology (top 5):
GO:0004114 - 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity
GO:0004118 - 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
GO:0005829 - cytosol
GO:0006198 - cAMP catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1247128

NEB2
Neurabin-2

2

4

High-throughput

0.584

High

92626

AKAP5
A-kinase anchor protein 5

1

2

Small-scale

0.479

High

771429

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

1

Small-scale

0.479

High

1029230

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

1

Small-scale

0.479

High

1223645

DLG4
Disks large homolog 4

1

1

Small-scale

0.479

High

1298124

APH1B
Gamma-secretase subunit APH-1B

1

1

Small-scale

0.479

High

1298199

Q8K1M3
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

3

Small-scale

0.479

High

420106

PRIO
Major prion protein

1

0

Small-scale

0.458

High

723466

SSR3
Somatostatin receptor type 3

1

1

High-throughput

0.437

High

1297459

APH1A
Gamma-secretase subunit APH-1A

1

1

Small-scale

0.437

High


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Last updated: 11Aug2025