Protein: FIG4
Polyphosphoinositide phosphatase (EC 3.1.3.-) (EC 3.1.3.36) (EC 3.1.3.86) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3) (Serine-protein phosphatase FIG4) (EC 3.1.3.16)

Gene: FIG4
Organism: Homo sapiens
Interactions: 25
UniProt ID: Q92562

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004439 - phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005811 - lipid droplet
GO:0006661 - phosphatidylinositol biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

997430

VAC14
Protein VAC14 homolog

6

1

Small-scale

0.735

High

1267345

FYV1
1-phosphatidylinositol 3-phosphate 5-kinase

5

3

Small-scale

0.712

High

1267344

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.580

High

556717

ANK1
Ankyrin-1

2

1

High-throughput

0.574

High

1267343

SNX27
Sorting nexin-27

1

3

High-throughput

0.536

High

228226

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.533

High

395354

A4
Amyloid-beta precursor protein

1

1

Small-scale

0.501

High

1267347

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

845124

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.479

High

1044406

PTC1
Protein patched homolog 1

1

1

Small-scale

0.479

High

1188332

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.479

High

1267342

MY18A
Unconventional myosin-XVIIIa

1

0

High-throughput

0.458

High

308937

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.437

High

969892

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.437

High

1043132

CUL4A
Cullin-4A

1

1

High-throughput

0.437

High

1267346

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

92410

E9PDH4
Phosphoinositide kinase, FYVE-type zinc finger containing

1

3

High-throughput

0.407

High

317487

YETS4
YEATS domain-containing protein 4

1

0

High-throughput

0.279

Low

813642

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

986828

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.279

Low

1069454

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.279

Low

1093030

CSPP1
Centrosome and spindle pole-associated protein 1

1

0

High-throughput

0.279

Low

847864

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.249

Low

1107788

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

0

High-throughput

0.249

Low

1245020

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024