Protein: GNAO
Guanine nucleotide-binding protein G(o) subunit alpha (EC 3.6.5.-)

Gene: GNAO, Gnao1
Organism: Mus musculus
Interactions: 21
UniProt ID: P18872

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0003925 - G protein activity
GO:0005525 - GTP binding
GO:0005834 - heterotrimeric G-protein complex
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

617637

RGS16
Regulator of G-protein signaling 16

1

20

Small-scale

0.692

High

617639

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

5

High-throughput

0.691

High

104460

SYGP1
Ras/Rap GTPase-activating protein SynGAP

3

12

High-throughput

0.667

High

617642

DLG4
Disks large homolog 4

3

4

High-throughput

0.650

High

554287

PCP2
Purkinje cell protein 2

1

11

Small-scale

0.637

High

617638

RGS14
Regulator of G-protein signaling 14

1

20

High-throughput

0.618

High

108447

G3X9H5
Huntingtin

2

11

High-throughput

0.584

High

617644

NEB2
Neurabin-2

2

7

High-throughput

0.584

High

617641

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

6

High-throughput

0.575

High

617648

GPSM2
G-protein-signaling modulator 2

1

14

Small-scale

0.555

High

617635

VAMP2
Vesicle-associated membrane protein 2

1

1

Small-scale

0.536

High

617646

CNKR2
Connector enhancer of kinase suppressor of ras 2

1

10

High-throughput

0.536

High

617634

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

20

Small-scale

0.501

High

617636

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

20

Small-scale

0.501

High

97356

PRRT2
Proline-rich transmembrane protein 2

1

8

High-throughput

0.479

High

551377

A4
Amyloid-beta precursor protein

1

6

Small-scale

0.479

High

617643

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

0

Small-scale

0.458

High

617640

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

5

High-throughput

0.437

High

617645

FACD2
Fanconi anemia group D2 protein homolog

1

6

High-throughput

0.437

High

617647

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

3

High-throughput

0.437

High

439021

LDHA
L-lactate dehydrogenase A chain

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025