Protein: CNKR2
Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2)

Gene: CNKR2, Cnksr2
Organism: Mus musculus
Interactions: 51
UniProt ID: Q80YA9

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0009966 - regulation of signal transduction
GO:0014069 - postsynaptic density
GO:0019901 - protein kinase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1223600

DLG4
Disks large homolog 4

3

14

High-throughput

0.847

High

1190163

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

2

12

High-throughput

0.811

High

989415

CYH2
Cytohesin-2

2

20

Small-scale

0.789

High

1193804

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

11

High-throughput

0.789

High

60107

KALRN
Kalirin

1

17

High-throughput

0.691

High

148524

CYH3
Cytohesin-3

1

20

High-throughput

0.691

High

548962

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

14

High-throughput

0.691

High

704226

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

14

High-throughput

0.691

High

811951

ZO1
Tight junction protein 1

1

20

High-throughput

0.691

High

993941

KPCG
Protein kinase C gamma type

1

19

High-throughput

0.691

High

996600

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

13

High-throughput

0.691

High

999791

DLG3
Disks large homolog 3

1

13

High-throughput

0.691

High

1013645

TNIK
Traf2 and NCK-interacting protein kinase

1

20

High-throughput

0.691

High

1229297

GIT1
ARF GTPase-activating protein GIT1

1

17

High-throughput

0.691

High

1281867

LRRC7
Leucine-rich repeat-containing protein 7

1

7

High-throughput

0.691

High

1282975

DLG1
Disks large homolog 1

1

13

High-throughput

0.691

High

1282977

BAIP2
BAR/IMD domain-containing adapter protein 2

1

14

High-throughput

0.691

High

1282978

TENR
Tenascin-R

1

9

High-throughput

0.691

High

1282979

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

20

High-throughput

0.691

High

1282981

DLG2
Disks large homolog 2

1

16

High-throughput

0.691

High

1282982

RHEB
GTP-binding protein Rheb

1

15

High-throughput

0.691

High

1282985

ARHG7
Rho guanine nucleotide exchange factor 7

1

18

High-throughput

0.691

High

1282986

MINK1
Misshapen-like kinase 1

1

20

High-throughput

0.691

High

1282988

CYH1
Cytohesin-1

1

20

High-throughput

0.691

High

1221406

CSK21
Casein kinase II subunit alpha

1

10

High-throughput

0.618

High

1190882

CDKL5
Cyclin-dependent kinase-like 5

1

12

High-throughput

0.618

High

104582

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

19

High-throughput

0.611

High

1282984

DLGP1
Disks large-associated protein 1

2

12

High-throughput

0.611

High

947836

RHG39
Rho GTPase-activating protein 39

2

9

Small-scale

0.558

High

86356

B9EKJ1
Spectrin alpha chain, non-erythrocytic 1

1

20

High-throughput

0.553

High

1253393

TAOK2
Serine/threonine-protein kinase TAO2

1

20

High-throughput

0.553

High

470779

NFL
Neurofilament light polypeptide

1

13

High-throughput

0.536

High

481007

PGK1
Phosphoglycerate kinase 1

1

2

High-throughput

0.536

High

578755

GLNA
Glutamine synthetase

1

1

High-throughput

0.536

High

617646

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

1

10

High-throughput

0.536

High

983635

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

12

High-throughput

0.536

High

990004

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1197975

LRIG2
Leucine-rich repeats and immunoglobulin-like domains protein 2

1

1

High-throughput

0.536

High

1222996

AP180
Clathrin coat assembly protein AP180

1

6

High-throughput

0.536

High

1223944

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

20

High-throughput

0.536

High

1229235

GRM4
Metabotropic glutamate receptor 4

1

1

High-throughput

0.536

High

1229319

Q68FG2
Spectrin beta chain

1

20

High-throughput

0.536

High

1282980

PARN
Poly(A)-specific ribonuclease PARN

1

1

High-throughput

0.536

High

1282983

PARK7
Parkinson disease protein 7 homolog

1

2

High-throughput

0.536

High

597659

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

20

High-throughput

0.514

High

855297

SYT1
Synaptotagmin-1

1

0

High-throughput

0.513

High

858175

AINX
Alpha-internexin

1

14

High-throughput

0.489

High

1221911

CAPR1
Caprin-1

1

5

High-throughput

0.489

High

1230428

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

16

High-throughput

0.479

High

1282987

SRCN1
SRC kinase signaling inhibitor 1

1

3

High-throughput

0.445

High

1282976

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

16

High-throughput

0.437

High


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Last updated: 11Aug2025