Protein: ARBK1
Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein-coupled receptor kinase 2)

Gene: ARBK1, Grk2
Organism: Mus musculus
Interactions: 15
UniProt ID: Q99MK8

Gene Ontology (top 5):
GO:0002026 - regulation of the force of heart contraction
GO:0002029 - desensitization of G protein-coupled receptor signaling pathway
GO:0003108 - negative regulation of the force of heart contraction by chemical signal
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1229973

BRSK2
Serine/threonine-protein kinase BRSK2

1

15

High-throughput

0.618

High

861894

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

16

Small-scale

0.561

High

97749

E9PXB7
E3 ubiquitin-protein ligase

1

16

Small-scale

0.512

High

1408878

SCNNB
Epithelial sodium channel subunit beta

1

2

Small-scale

0.501

High

662991

MDM2
E3 ubiquitin-protein ligase Mdm2

1

5

Small-scale

0.479

High

983642

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

9

Small-scale

0.479

High

1188906

STING
Stimulator of interferon genes protein

1

4

High-throughput

0.479

High

1221330

PPP5
Serine/threonine-protein phosphatase 5

1

13

High-throughput

0.479

High

1247174

NEB2
Neurabin-2

1

13

Small-scale

0.479

High

1341674

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

5

High-throughput

0.479

High

1408876

PK3CG
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

1

3

Small-scale

0.479

High

992426

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

0

Small-scale

0.458

High

1408877

ITA2B
Integrin alpha-IIb

1

3

High-throughput

0.457

High

108835

G3X9H5
Huntingtin

1

5

High-throughput

0.437

High

1296250

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

2

High-throughput

0.437

High


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Last updated: 11Aug2025