Protein: TAP1
Antigen peptide transporter 1 (APT1) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 2) (Peptide supply factor 1) (Peptide transporter PSF1) (PSF-1) (Peptide transporter TAP1) (Peptide transporter involved in antigen processing 1) (Really interesting new gene 4 protein) (RING4)

Gene: TAP1
Organism: Homo sapiens
Interactions: 132
UniProt ID: Q03518

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0005524 - ATP binding
GO:0005743 - mitochondrial inner membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

976712

TAP2
Antigen peptide transporter 2

12

15

Small-scale

0.978

High

182268

TPSN
Tapasin

6

6

Small-scale

0.732

High

671791

PDIA3
Protein disulfide-isomerase A3

4

2

Small-scale

0.694

High

654274

CALX
Calnexin

3

4

Small-scale

0.667

High

976711

TAP1
Antigen peptide transporter 1

1

14

Small-scale

0.647

High

501039

IRF1
Interferon regulatory factor 1

5

3

Small-scale

0.641

High

382396

HLAA
HLA class I histocompatibility antigen, A alpha chain

3

9

Small-scale

0.640

High

653564

CALR
Calreticulin

2

4

Small-scale

0.611

High

674141

HMOX2
Heme oxygenase 2

2

2

High-throughput

0.611

High

976723

SOAT
Sodium-dependent organic anion transporter

2

1

High-throughput

0.606

High

976734

RN19B
E3 ubiquitin-protein ligase RNF19B

2

4

High-throughput

0.606

High

976773

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

2

High-throughput

0.606

High

901862

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

2

16

Small-scale

0.601

High

536511

IRF2
Interferon regulatory factor 2

3

3

Small-scale

0.585

High

883975

GEMI4
Gem-associated protein 4

2

0

High-throughput

0.580

High

976748

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.580

High

976767

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.580

High

976779

X5CMH5
ABC-type antigen peptide transporter

1

14

High-throughput

0.575

High

674786

GRPR
Gastrin-releasing peptide receptor

2

5

High-throughput

0.574

High

786319

STAT1
Signal transducer and activator of transcription 1-alpha/beta

2

0

Small-scale

0.559

High

976716

AQP6
Aquaporin-6

2

20

High-throughput

0.553

High

976719

NTCP
Hepatic sodium/bile acid cotransporter

2

1

High-throughput

0.553

High

976747

GP152
Probable G-protein coupled receptor 152

2

13

High-throughput

0.553

High

591213

ACM3
Muscarinic acetylcholine receptor M3

1

1

High-throughput

0.541

High

171979

GP182
G-protein coupled receptor 182

1

11

High-throughput

0.536

High

207040

XRCC3
DNA repair protein XRCC3

1

1

High-throughput

0.536

High

310607

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

2

High-throughput

0.536

High

330662

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

3

High-throughput

0.536

High

452221

HMOX1
Heme oxygenase 1

1

2

High-throughput

0.536

High

489400

BCL2
Apoptosis regulator Bcl-2

1

1

High-throughput

0.536

High

537731

INSRR
Insulin receptor-related protein

1

5

High-throughput

0.536

High

558716

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

5

High-throughput

0.536

High

561558

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

6

High-throughput

0.536

High

580348

TSN8
Tetraspanin-8

1

5

High-throughput

0.536

High

976715

KLRD1
Natural killer cells antigen CD94

1

11

High-throughput

0.536

High

976718

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

1

High-throughput

0.536

High

976730

ATLA3
Atlastin-3

1

1

High-throughput

0.536

High

976741

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

2

High-throughput

0.536

High

976746

HUMMR
Protein MGARP

1

1

High-throughput

0.536

High

976749

AQP3
Aquaporin-3

1

20

High-throughput

0.536

High

976753

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

3

High-throughput

0.536

High

976759

S22A4
Solute carrier family 22 member 4

1

6

High-throughput

0.536

High

976769

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.536

High

976770

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

2

High-throughput

0.536

High

976772

CLC4E
C-type lectin domain family 4 member E

1

3

High-throughput

0.536

High

976778

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

1

High-throughput

0.536

High

976750

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

0

High-throughput

0.518

High

126798

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

196765

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.513

High

678347

GDIA
Rab GDP dissociation inhibitor alpha

1

0

High-throughput

0.513

High

739080

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

838782

EMD
Emerin

1

0

High-throughput

0.513

High

976724

SHSL1
Protein shisa-like-1

1

0

High-throughput

0.513

High

976732

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.513

High

976735

MBOA1
Lysophospholipid acyltransferase 1

1

0

High-throughput

0.513

High

976744

TLC3A
TLC domain-containing protein 3A

1

0

High-throughput

0.513

High

976751

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

976754

BSCL2
Seipin

1

0

High-throughput

0.513

High

423209

PDIA1
Protein disulfide-isomerase

1

3

Small-scale

0.500

High

146337

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

1

High-throughput

0.489

High

156820

FFAR1
Free fatty acid receptor 1

1

10

High-throughput

0.489

High

362134

ACHA
Acetylcholine receptor subunit alpha

1

3

High-throughput

0.489

High

686286

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

2

High-throughput

0.489

High

723293

APJ
Apelin receptor

1

3

High-throughput

0.489

High

813934

GPR12
G-protein coupled receptor 12

1

5

High-throughput

0.489

High

856598

EFNA5
Ephrin-A5

1

1

High-throughput

0.489

High

876107

PAR2
Proteinase-activated receptor 2

1

10

High-throughput

0.489

High

976727

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

1

High-throughput

0.489

High

976738

P2RY8
P2Y purinoceptor 8

1

10

High-throughput

0.489

High

976739

TMM25
Transmembrane protein 25

1

1

High-throughput

0.489

High

976740

S22A9
Organic anion transporter 7

1

6

High-throughput

0.489

High

976755

OPALI
Opalin

1

1

High-throughput

0.489

High

976764

LPAR2
Lysophosphatidic acid receptor 2

1

6

High-throughput

0.489

High

976765

GPR35
G-protein coupled receptor 35

1

8

High-throughput

0.489

High

976766

TMM9B
Transmembrane protein 9B

1

2

High-throughput

0.489

High

976774

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

1

High-throughput

0.489

High

976776

GPR45
Probable G-protein coupled receptor 45

1

4

High-throughput

0.489

High

216712

CREB3
Cyclic AMP-responsive element-binding protein 3

1

0

High-throughput

0.486

High

435055

SP1
Transcription factor Sp1

1

2

Small-scale

0.479

High

570321

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

9

Small-scale

0.479

High

651010

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

668614

PML
Protein PML

1

1

High-throughput

0.479

High

799973

VDAC2
Voltage-dependent anion-selective channel protein 2

1

3

High-throughput

0.479

High

863210

COPB
Coatomer subunit beta

1

1

Small-scale

0.479

High

893924

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

900401

RHOA
Transforming protein RhoA

1

17

High-throughput

0.479

High

976713

TF65
Transcription factor p65

1

3

Small-scale

0.479

High

976714

PDIA2
Protein disulfide-isomerase A2

1

3

Small-scale

0.479

High

976745

RDH11
Retinol dehydrogenase 11

1

3

High-throughput

0.479

High

976771

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

976777

COPG1
Coatomer subunit gamma-1

1

1

Small-scale

0.479

High

656054

PSB8
Proteasome subunit beta type-8

1

5

Small-scale

0.464

High

976720

KS6A1
Ribosomal protein S6 kinase alpha-1

1

0

High-throughput

0.458

High

976722

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

976737

THOC4
THO complex subunit 4

1

0

Small-scale

0.458

High

976761

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

976762

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

353925

IGHM
Immunoglobulin heavy constant mu

1

1

High-throughput

0.445

High

976752

ERP27
Endoplasmic reticulum resident protein 27

1

3

Small-scale

0.445

High

181190

NUP42
Nucleoporin NUP42

1

0

Small-scale

0.438

High

205295

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

397922

ISG15
Ubiquitin-like protein ISG15

1

7

High-throughput

0.437

High

587541

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

3

Small-scale

0.437

High

940806

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.437

High

976729

VIR
Protein virilizer homolog

1

2

High-throughput

0.437

High

976731

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

976736

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

976742

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

1

Small-scale

0.437

High

976763

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

656108

PSB9
Proteasome subunit beta type-9

1

5

Small-scale

0.417

High

102392

G3V234
Retinol dehydrogenase 11

1

3

High-throughput

0.407

High

111101

I3L4P8
Heme oxygenase 2

1

2

High-throughput

0.407

High

976725

Q5JSD2
Voltage-dependent anion-selective channel protein 2

1

2

High-throughput

0.407

High

890925

SYCY2
Syncytin-2

2

0

High-throughput

0.316

High

976728

LCE2C
Late cornified envelope protein 2C

2

0

High-throughput

0.316

High

976768

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

976717

THOC5
THO complex subunit 5 homolog

1

0

Small-scale

0.288

High

316326

TYDP2
Tyrosyl-DNA phosphodiesterase 2

1

0

High-throughput

0.282

High

976756

MDFI
MyoD family inhibitor

1

0

High-throughput

0.282

High

976757

KR412
Keratin-associated protein 4-12

1

0

High-throughput

0.282

High

296900

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.279

Low

565915

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.279

Low

976726

CSCL2
CSC1-like protein 2

1

0

High-throughput

0.279

Low

976733

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

976743

OR2M7
Olfactory receptor 2M7

1

0

High-throughput

0.279

Low

976775

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

147717

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

0

High-throughput

0.269

Low

359871

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

976721

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

976758

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.249

Low

976760

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024