Protein: AP2S1
AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma-adaptin 3b) (Sigma2-adaptin)

Gene: AP2S1
Organism: Mus musculus
Interactions: 35
UniProt ID: P62743

Gene Ontology (top 5):
GO:0006886 - intracellular protein transport
GO:0009898 - cytoplasmic side of plasma membrane
GO:0016192 - vesicle-mediated transport
GO:0030122 - AP-2 adaptor complex
GO:0035615 - clathrin adaptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604478

AP2A2
AP-2 complex subunit alpha-2

1

20

High-throughput

0.618

High

977885

AP2S1
AP-2 complex subunit sigma

1

12

High-throughput

0.618

High

977888

AP2M1
AP-2 complex subunit mu

1

19

High-throughput

0.618

High

237091

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

977886

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

7

High-throughput

0.479

High

977889

TERA
Transitional endoplasmic reticulum ATPase

1

8

High-throughput

0.479

High

977905

ATG5
Autophagy protein 5

1

3

Small-scale

0.479

High

977893

SC6A4
Sodium-dependent serotonin transporter

1

0

High-throughput

0.458

High

147480

DPYL2
Dihydropyrimidinase-related protein 2

1

1

Small-scale

0.437

High

312821

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.437

High

398261

CFAD
Complement factor D

1

3

High-throughput

0.437

High

631781

MTAP2
Microtubule-associated protein 2

1

12

High-throughput

0.437

High

693422

MAP4
Microtubule-associated protein 4

1

13

High-throughput

0.437

High

977887

DNJA1
DnaJ homolog subfamily A member 1

1

1

High-throughput

0.437

High

977890

STING
Stimulator of interferon genes protein

1

3

High-throughput

0.437

High

977891

TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

1

2

High-throughput

0.437

High

977896

Q7TMG8
Glioblastoma amplified sequence

1

1

High-throughput

0.437

High

977897

UBP2L
Ubiquitin-associated protein 2-like

1

5

High-throughput

0.437

High

977898

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

1

1

High-throughput

0.437

High

977899

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

2

High-throughput

0.437

High

977901

Q8BNP7
Adenomatous polyposis coli protein

1

2

High-throughput

0.437

High

977902

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.437

High

977904

EED
Polycomb protein EED

1

5

High-throughput

0.437

High

977906

RBP2
E3 SUMO-protein ligase RanBP2

1

1

High-throughput

0.437

High

977907

MAP1A
Microtubule-associated protein 1A

1

1

High-throughput

0.437

High

977908

RUVB2
RuvB-like 2

1

3

High-throughput

0.437

High

915518

HMGA2
High mobility group protein HMGI-C

1

1

High-throughput

0.407

High

977900

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

7

High-throughput

0.407

High

531206

GSTM1
Glutathione S-transferase Mu 1

1

0

High-throughput

0.249

Low

926885

STMN1
Stathmin

1

0

High-throughput

0.249

Low

977892

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.249

Low

977894

PCNP
PEST proteolytic signal-containing nuclear protein

1

0

High-throughput

0.249

Low

977895

DHX29
ATP-dependent RNA helicase DHX29

1

0

High-throughput

0.249

Low

977903

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025