Protein: GRM5
Metabotropic glutamate receptor 5 (mGluR5)

Gene: GRM5
Organism: Mus musculus
Interactions: 17
UniProt ID: Q3UVX5

Gene Ontology (top 5):
GO:0001639 - PLC activating G protein-coupled glutamate receptor activity
GO:0002029 - desensitization of G protein-coupled receptor signaling pathway
GO:0004930 - G protein-coupled receptor activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1190959

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

4

High-throughput

0.611

High

1190967

HOME1
Homer protein homolog 1

2

11

Small-scale

0.611

High

1013575

TNIK
Traf2 and NCK-interacting protein kinase

1

1

High-throughput

0.536

High

1190124

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

5

High-throughput

0.536

High

632512

KPCA
Protein kinase C alpha type

1

8

Small-scale

0.501

High

1190960

ACTN1
Alpha-actinin-1

1

2

Small-scale

0.481

High

104528

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

1

High-throughput

0.479

High

147949

STXB1
Syntaxin-binding protein 1

1

2

High-throughput

0.479

High

591133

MET
Hepatocyte growth factor receptor

1

5

High-throughput

0.479

High

723369

SSR3
Somatostatin receptor type 3

1

6

High-throughput

0.479

High

1190963

LRC4C
Leucine-rich repeat-containing protein 4C

1

2

High-throughput

0.479

High

1190966

HOME2
Homer protein homolog 2

1

12

Small-scale

0.479

High

420093

PRIO
Major prion protein

1

0

Small-scale

0.458

High

1190964

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

Small-scale

0.458

High

1190965

SRCN1
SRC kinase signaling inhibitor 1

1

4

High-throughput

0.445

High

1190962

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

5

High-throughput

0.437

High

1190961

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025