Protein: DHPR
Dihydropteridine reductase (EC 1.5.1.34) (HDHPR) (Quinoid dihydropteridine reductase) (Short chain dehydrogenase/reductase family 33C member 1)

Gene: DHPR, QDPR
Organism: Homo sapiens
Interactions: 27
UniProt ID: P09417

Gene Ontology (top 5):
GO:0004155 - 6,7-dihydropteridine reductase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006520 - amino acid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

481017

DHPR
Dihydropteridine reductase

1

2

High-throughput

0.698

High

481031

AN13A
Ankyrin repeat domain-containing protein 13A

2

0

High-throughput

0.559

High

481024

CUL1
Cullin-1

1

1

High-throughput

0.536

High

481025

CUL3
Cullin-3

1

1

High-throughput

0.536

High

375108

RASK
GTPase KRas

1

0

High-throughput

0.518

High

481026

CASP8
Caspase-8

1

0

High-throughput

0.518

High

387211

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.513

High

481018

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

481027

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

481028

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

481030

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

481033

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

481037

ELF5
ETS-related transcription factor Elf-5

1

0

High-throughput

0.493

High

361031

PH4H
Phenylalanine-4-hydroxylase

1

0

Small-scale

0.460

High

421356

A4
Amyloid-beta precursor protein

1

0

Small-scale

0.458

High

481021

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

481022

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

481023

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.458

High

481029

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

481036

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

481020

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

481032

RL3R2
Relaxin-3 receptor 2

1

0

High-throughput

0.282

High

481019

EGLN
Endoglin

1

0

High-throughput

0.279

Low

481034

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

0

High-throughput

0.279

Low

105169

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

481035

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025