Protein: ELF5
ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2)

Gene: ELF5
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q9UKW6

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001712 - ectodermal cell fate commitment

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1436928

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

9

High-throughput

0.618

High

1329936

SIR6
NAD-dependent protein deacylase sirtuin-6

2

0

High-throughput

0.613

High

1449060

GLRX2
Glutaredoxin-2, mitochondrial

2

0

High-throughput

0.580

High

1067825

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.561

High

274059

CREST
Calcium-responsive transactivator

1

20

High-throughput

0.541

High

958375

ARP2
Actin-related protein 2

1

1

High-throughput

0.541

High

1156714

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

Small-scale

0.541

High

1159571

NFE2
Transcription factor NF-E2 45 kDa subunit

1

20

High-throughput

0.541

High

1448808

UBQL4
Ubiquilin-4

1

1

High-throughput

0.541

High

969717

RS15A
Small ribosomal subunit protein uS8

1

0

High-throughput

0.518

High

1410842

NRIP2
Nuclear receptor-interacting protein 2

1

0

High-throughput

0.518

High

1048751

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.513

High

1367997

SFRP3
Secreted frizzled-related protein 3

1

1

High-throughput

0.508

High

481037

DHPR
Dihydropteridine reductase

1

0

High-throughput

0.493

High

1403150

CRBN
Protein cereblon

1

0

Small-scale

0.480

High

154771

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

161524

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

180959

TIF1A
Transcription intermediary factor 1-alpha

1

20

High-throughput

0.479

High

194627

KDM6A
Lysine-specific demethylase 6A

1

7

High-throughput

0.479

High

282800

E2F6
Transcription factor E2F6

1

5

High-throughput

0.479

High

345021

WIZ
Protein Wiz

1

9

High-throughput

0.479

High

728475

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

High-throughput

0.479

High

903278

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

18

High-throughput

0.479

High

916116

NKX25
Homeobox protein Nkx-2.5

1

17

High-throughput

0.479

High

1032792

SATB1
DNA-binding protein SATB1

1

6

High-throughput

0.479

High

1047883

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

1061919

TLE5
TLE family member 5

1

14

High-throughput

0.479

High

1149762

SSXT
Protein SSXT

1

20

High-throughput

0.479

High

1228290

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

1245185

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

4

High-throughput

0.479

High

1257167

PAXI1
PAX-interacting protein 1

1

16

High-throughput

0.479

High

1288009

PB1
Protein polybromo-1

1

20

High-throughput

0.479

High

1338284

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

1338782

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

1357481

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

8

High-throughput

0.479

High

1368278

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

1368414

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

1370767

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

20

High-throughput

0.479

High

1392085

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

14

High-throughput

0.479

High

1396148

Z512B
Zinc finger protein 512B

1

12

High-throughput

0.479

High

1410250

TBL1Y
F-box-like/WD repeat-containing protein TBL1Y

1

17

High-throughput

0.479

High

1434509

ZN644
Zinc finger protein 644

1

9

High-throughput

0.479

High

1446431

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

1461296

TRI33
E3 ubiquitin-protein ligase TRIM33

1

20

High-throughput

0.479

High

1461297

SATB2
DNA-binding protein SATB2

1

6

High-throughput

0.479

High

1461298

ZN281
Zinc finger protein 281

1

11

High-throughput

0.479

High

299424

FLOT1
Flotillin-1

1

10

High-throughput

0.457

High

1124943

FLOT2
Flotillin-2

1

10

High-throughput

0.457

High


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Last updated: 11Aug2025