Protein: ACS2L
Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1) (Propionate--CoA ligase) (EC 6.2.1.17)

Gene: ACS2L, ACSS1
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q9NUB1

Gene Ontology (top 5):
GO:0003987 - acetate-CoA ligase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006068 - ethanol catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1432191

IPYR2
Inorganic pyrophosphatase 2, mitochondrial

3

1

High-throughput

0.667

High

1162581

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

3

1

Small-scale

0.640

High

275398

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

2

1

High-throughput

0.628

High

533002

CH60
60 kDa heat shock protein, mitochondrial

2

5

High-throughput

0.628

High

1066031

VAC14
Protein VAC14 homolog

3

1

High-throughput

0.616

High

1414101

TMM70
Transmembrane protein 70, mitochondrial

2

0

High-throughput

0.602

High

284623

ECI2
Enoyl-CoA delta isomerase 2

1

0

High-throughput

0.586

High

869252

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

1

High-throughput

0.536

High

1449507

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

1

2

Small-scale

0.536

High

1292772

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1389018

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

1232601

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

279940

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

471274

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

1403446

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

894196

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

1368496

CBP
CREB-binding protein

1

3

Small-scale

0.439

High

106719

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

589816

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

696634

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

769301

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

879514

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

1255742

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1404678

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025