Protein: PTN6
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (70Z-SHP) (Hematopoietic cell protein-tyrosine phosphatase) (PTPTY-42) (Protein-tyrosine phosphatase 1C) (PTP-1C) (SH-PTP1) (SHP-1)

Gene: PTN6, Ptpn6
Organism: Mus musculus
Interactions: 29
UniProt ID: P29351

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0000278 - mitotic cell cycle
GO:0001784 - phosphotyrosine residue binding
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0002924 - negative regulation of humoral immune response mediated by circulating immunoglobulin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

665993

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

20

Small-scale

0.740

High

665987

LCP2
Lymphocyte cytosolic protein 2

1

3

Small-scale

0.724

High

665982

LIRB3
Leukocyte immunoglobulin-like receptor subfamily B member 3

6

20

Small-scale

0.721

High

665980

PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

1

4

Small-scale

0.646

High

665983

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

3

13

Small-scale

0.640

High

639436

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.618

High

665977

STAT1
Signal transducer and activator of transcription 1

1

15

Small-scale

0.618

High

665978

STAT3
Signal transducer and activator of transcription 3

1

16

Small-scale

0.618

High

665979

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.618

High

665989

JAK2
Tyrosine-protein kinase JAK2

1

20

Small-scale

0.618

High

665991

LRB4A
Leukocyte immunoglobulin-like receptor subfamily B member 4A

2

20

Small-scale

0.608

High

665992

FCRL5
Fc receptor-like protein 5

2

20

Small-scale

0.584

High

665981

DOK1
Docking protein 1

1

15

Small-scale

0.561

High

660215

I23O1
Indoleamine 2,3-dioxygenase 1

1

1

Small-scale

0.536

High

665976

CD22
B-cell receptor CD22

2

19

Small-scale

0.504

High

665996

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

2

Small-scale

0.500

High

610140

CD3E
T-cell surface glycoprotein CD3 epsilon chain

1

1

Small-scale

0.479

High

621829

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

4

Small-scale

0.479

High

665984

STING
Stimulator of interferon genes protein

1

4

High-throughput

0.479

High

665985

CBLB
E3 ubiquitin-protein ligase CBL-B

1

13

Small-scale

0.479

High

665988

TRAF3
TNF receptor-associated factor 3

1

8

Small-scale

0.479

High

665994

FACD2
Fanconi anemia group D2 protein homolog

1

3

High-throughput

0.479

High

665998

GAB2
GRB2-associated-binding protein 2

1

14

Small-scale

0.479

High

665990

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

Small-scale

0.458

High

93615

E9Q604
Integrin alpha M

1

11

High-throughput

0.457

High

665997

ITA2B
Integrin alpha-IIb

1

11

High-throughput

0.457

High

665995

LAIR1
Leukocyte-associated immunoglobulin-like receptor 1

1

20

Small-scale

0.457

High

665986

CARL2
Capping protein, Arp2/3 and myosin-I linker protein 2

1

3

Small-scale

0.445

High

60475

A5D6Q2
Ncoa3 protein

1

0

Small-scale

0.251

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024