Protein: UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (UQCRFS1 mitochondrial targeting sequence) (UQCRFS1 MTS) (Ubiquinol-cytochrome c reductase 8 kDa protein)]

Gene: UCRI, UQCRFS1
Organism: Homo sapiens
Interactions: 194
UniProt ID: P47985

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
GO:0006122 - mitochondrial electron transport, ubiquinol to cytochrome c
GO:0008121 - quinol-cytochrome-c reductase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

357853

CYB
Cytochrome b

1

1

High-throughput

0.691

High

577952

QCR7
Cytochrome b-c1 complex subunit 7

1

1

High-throughput

0.691

High

869257

QCR9
Cytochrome b-c1 complex subunit 9

1

1

High-throughput

0.691

High

869177

LYRM7
Complex III assembly factor LYRM7

5

0

Small-scale

0.684

High

168975

QCR8
Cytochrome b-c1 complex subunit 8

1

0

High-throughput

0.656

High

869247

TRXR2
Thioredoxin reductase 2, mitochondrial

1

0

High-throughput

0.656

High

869157

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

2

1

High-throughput

0.611

High

869165

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

1

High-throughput

0.611

High

156438

ACPM
Acyl carrier protein, mitochondrial

2

1

High-throughput

0.601

High

653182

HEMH
Ferrochelatase, mitochondrial

2

1

High-throughput

0.601

High

786022

LONM
Lon protease homolog, mitochondrial

2

1

High-throughput

0.601

High

869214

EFGM
Elongation factor G, mitochondrial

2

2

High-throughput

0.601

High

869215

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

2

2

High-throughput

0.601

High

842191

THIM
3-ketoacyl-CoA thiolase, mitochondrial

2

0

High-throughput

0.585

High

869173

SYAM
Alanine--tRNA ligase, mitochondrial

2

0

High-throughput

0.585

High

869201

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

2

0

High-throughput

0.585

High

301862

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

2

0

High-throughput

0.576

High

869178

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

2

0

High-throughput

0.576

High

869199

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

2

0

High-throughput

0.576

High

869148

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

2

High-throughput

0.571

High

328295

NDUB4
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

2

0

High-throughput

0.559

High

559906

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

0

High-throughput

0.559

High

869241

SFXN1
Sideroflexin-1

2

0

High-throughput

0.559

High

801218

HSPA9
Stress-70 protein, mitochondrial

1

2

High-throughput

0.554

High

869175

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

High-throughput

0.547

High

143814

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

1

High-throughput

0.536

High

156196

CO72L
Cytochrome c oxidase subunit 7A2-like, mitochondrial

1

1

High-throughput

0.536

High

166631

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

4

High-throughput

0.536

High

281130

NDK6
Nucleoside diphosphate kinase 6

1

1

High-throughput

0.536

High

425785

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

2

High-throughput

0.536

High

554785

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

1

High-throughput

0.536

High

572350

CX7A2
Cytochrome c oxidase subunit 7A2, mitochondrial

1

1

High-throughput

0.536

High

725591

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

2

High-throughput

0.536

High

856215

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.536

High

869142

SYHM
Histidine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

869160

SYLM
Leucine--tRNA ligase, mitochondrial

1

2

High-throughput

0.536

High

869161

PDK1
[Pyruvate dehydrogenase

1

4

High-throughput

0.536

High

869162

PDK2
[Pyruvate dehydrogenase

1

4

High-throughput

0.536

High

869163

PDK3
[Pyruvate dehydrogenase

1

4

High-throughput

0.536

High

869169

ACSF3
Malonate--CoA ligase ACSF3, mitochondrial

1

2

High-throughput

0.536

High

869176

SYVM
Valine--tRNA ligase, mitochondrial

1

2

High-throughput

0.536

High

869179

ACD10
Acyl-CoA dehydrogenase family member 10

1

1

High-throughput

0.536

High

869191

GUF1
Translation factor GUF1, mitochondrial

1

1

High-throughput

0.536

High

869206

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

1

High-throughput

0.536

High

869207

NSUN4
5-cytosine rRNA methyltransferase NSUN4

1

1

High-throughput

0.536

High

869208

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

2

High-throughput

0.536

High

869209

ECHD3
Enoyl-CoA hydratase domain-containing protein 3, mitochondrial

1

1

High-throughput

0.536

High

869211

SYMM
Methionine--tRNA ligase, mitochondrial

1

3

High-throughput

0.536

High

869224

SYTM
Threonine--tRNA ligase, mitochondrial

1

2

High-throughput

0.536

High

869238

NSUN3
tRNA

1

1

High-throughput

0.536

High

869243

RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial

1

1

High-throughput

0.536

High

869250

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

869251

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

1

1

High-throughput

0.536

High

869252

ACS2L
Acetyl-coenzyme A synthetase 2-like, mitochondrial

1

1

High-throughput

0.536

High

869262

BCS1
Mitochondrial chaperone BCS1

1

1

High-throughput

0.536

High

869189

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.530

High

869231

ISCU
Iron-sulfur cluster assembly enzyme ISCU

1

0

High-throughput

0.530

High

61451

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.513

High

71714

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.513

High

177523

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.513

High

231213

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.513

High

278633

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.513

High

296106

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

1

0

High-throughput

0.513

High

322216

GLSK
Glutaminase kidney isoform, mitochondrial

1

0

High-throughput

0.513

High

350814

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.513

High

462768

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.513

High

559673

UNG
Uracil-DNA glycosylase

1

0

High-throughput

0.513

High

649871

ADRO
NADPH:adrenodoxin oxidoreductase, mitochondrial

1

0

High-throughput

0.513

High

846002

CACP
Carnitine O-acetyltransferase

1

0

High-throughput

0.513

High

869143

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.513

High

869146

DPOG1
DNA polymerase subunit gamma-1

1

0

High-throughput

0.513

High

869150

CP24A
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

1

0

High-throughput

0.513

High

869154

NNTM
NAD(P) transhydrogenase, mitochondrial

1

0

High-throughput

0.513

High

869155

TOP3A
DNA topoisomerase 3-alpha

1

0

High-throughput

0.513

High

869164

TAZ
Tafazzin

1

0

High-throughput

0.513

High

869166

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.513

High

869170

PPCEL
Prolyl endopeptidase-like

1

0

High-throughput

0.513

High

869172

SYEM
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

1

0

High-throughput

0.513

High

869180

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

0

High-throughput

0.513

High

869181

SYDM
Aspartate--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

869185

NDUF7
Protein arginine methyltransferase NDUFAF7, mitochondrial

1

0

High-throughput

0.513

High

869187

NDUAB
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

1

0

High-throughput

0.513

High

869188

DLP1
All trans-polyprenyl-diphosphate synthase PDSS2

1

0

High-throughput

0.513

High

869192

CBR4
3-oxoacyl-[acyl-carrier-protein] reductase

1

0

High-throughput

0.513

High

869195

CHDH
Choline dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

869196

ABHDB
sn-1-specific diacylglycerol lipase ABHD11

1

0

High-throughput

0.513

High

869198

NUBPL
Iron-sulfur cluster transfer protein NUBPL

1

0

High-throughput

0.513

High

869200

ALAT2
Alanine aminotransferase 2

1

0

High-throughput

0.513

High

869202

NUDT8
Mitochondrial coenzyme A diphosphatase NUDT8

1

0

High-throughput

0.513

High

869203

TFB1M
Dimethyladenosine transferase 1, mitochondrial

1

0

High-throughput

0.513

High

869204

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

1

0

High-throughput

0.513

High

869210

TRM2B
tRNA

1

0

High-throughput

0.513

High

869212

SYNM
Asparaginyl-tRNA synthetase

1

0

High-throughput

0.513

High

869216

CK5P1
Mitochondrial tRNA methylthiotransferase CDK5RAP1

1

0

High-throughput

0.513

High

869217

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

0

High-throughput

0.513

High

869218

MACD1
ADP-ribose glycohydrolase MACROD1

1

0

High-throughput

0.513

High

869219

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.513

High

869220

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.513

High

869221

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.513

High

869223

TR61B
tRNA

1

0

High-throughput

0.513

High

869227

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.513

High

869234

OSGL1
tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial

1

0

High-throughput

0.513

High

869235

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.513

High

869240

PGES2
Prostaglandin E synthase 2

1

0

High-throughput

0.513

High

869242

L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

869245

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.513

High

869249

D39U1
Epimerase family protein SDR39U1

1

0

High-throughput

0.513

High

869254

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.513

High

869255

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.513

High

869259

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

0

High-throughput

0.513

High

869260

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

869263

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

869264

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

High-throughput

0.513

High

869267

HEMK1
MTRF1L release factor glutamine methyltransferase

1

0

High-throughput

0.513

High

869268

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.513

High

774199

BASI
Basigin

1

0

High-throughput

0.493

High

302775

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

1

High-throughput

0.489

High

720968

CLIP1
CAP-Gly domain-containing linker protein 1

1

1

High-throughput

0.489

High

470915

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

576094

CX6B1
Cytochrome c oxidase subunit 6B1

1

1

High-throughput

0.479

High

869152

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

High-throughput

0.479

High

869232

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

1

High-throughput

0.479

High

869237

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.479

High

137673

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

279692

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

283816

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

443258

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.458

High

505420

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

720090

PURA2
Adenylosuccinate synthetase isozyme 2

1

0

High-throughput

0.458

High

822521

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

869149

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

869205

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.458

High

869222

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

869225

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

869229

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

869239

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

869248

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

0

Small-scale

0.458

High

869253

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

869183

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

1

High-throughput

0.445

High

353091

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

869145

CDK9
Cyclin-dependent kinase 9

1

1

High-throughput

0.437

High

869174

WIPI1
WD repeat domain phosphoinositide-interacting protein 1

1

1

Small-scale

0.437

High

869184

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

869190

PELI3
E3 ubiquitin-protein ligase pellino homolog 3

1

1

Small-scale

0.437

High

869228

TRI55
Tripartite motif-containing protein 55

1

1

High-throughput

0.437

High

869236

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

869244

PELI2
E3 ubiquitin-protein ligase pellino homolog 2

1

1

Small-scale

0.437

High

869265

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

1

High-throughput

0.437

High

485853

COX6C
Cytochrome c oxidase subunit 6C

1

0

Small-scale

0.426

High

844910

EAA2
Excitatory amino acid transporter 2

1

0

High-throughput

0.426

High

869158

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.426

High

869168

AL1L2
Mitochondrial 10-formyltetrahydrofolate dehydrogenase

1

0

High-throughput

0.426

High

869197

SPT20
Spermatogenesis-associated protein 20

1

0

High-throughput

0.426

High

869246

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.426

High

395671

ESR1
Estrogen receptor

2

0

High-throughput

0.298

High

776033

SOX5
Transcription factor SOX-5

1

0

High-throughput

0.282

High

869144

5HT6R
5-hydroxytryptamine receptor 6

1

0

High-throughput

0.282

High

869147

RELB
Transcription factor RelB

1

0

High-throughput

0.282

High

209506

SERA
D-3-phosphoglycerate dehydrogenase

1

0

High-throughput

0.279

Low

221925

FOXS1
Forkhead box protein S1

1

0

High-throughput

0.279

Low

369030

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.279

Low

485782

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

0

High-throughput

0.279

Low

772666

MYH9
Myosin-9

1

0

High-throughput

0.279

Low

869151

LTOR4
Ragulator complex protein LAMTOR4

1

0

High-throughput

0.279

Low

869153

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.279

Low

869159

RBM39
RNA-binding protein 39

1

0

High-throughput

0.279

Low

869186

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

869256

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.279

Low

869261

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.279

Low

869266

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

105541

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

208476

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.249

Low

489032

LKHA4
Leukotriene A-4 hydrolase

1

0

High-throughput

0.249

Low

536722

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.249

Low

582708

EZRI
Ezrin

1

0

High-throughput

0.249

Low

588157

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

694879

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

767653

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

798830

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.249

Low

845256

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

0

High-throughput

0.249

Low

869141

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

869156

CUL3
Cullin-3

1

0

High-throughput

0.249

Low

869167

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

869171

MIDN
Midnolin

1

0

High-throughput

0.249

Low

869182

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

869193

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low

869194

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

869213

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

869226

AP1M1
AP-1 complex subunit mu-1

1

0

High-throughput

0.249

Low

869230

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

869258

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

371438

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.232

Low

841107

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.232

Low

869233

RHBG
Ammonium transporter Rh type B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025