Protein: ESM3
Enhancer of split m3 protein (E(spl)m3) (HLH-m3)

Gene: ESM3, E(spl)m3-HLH
Organism: Drosophila melanogaster
Interactions: 27
UniProt ID: Q01068

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0002052 - positive regulation of neuroblast proliferation
GO:0005634 - nucleus
GO:0006355 - regulation of DNA-templated transcription
GO:0007219 - Notch signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

518489

AST4
Achaete-scute complex protein T4

2

20

Small-scale

0.800

High

518455

AST5
Achaete-scute complex protein T5

2

20

Small-scale

0.778

High

569354

HAIR
Protein hairy

1

17

Small-scale

0.724

High

594683

GROU
Protein groucho

5

20

Small-scale

0.706

High

1028538

ESM3
Enhancer of split m3 protein

2

17

Small-scale

0.689

High

486733

AST8
Achaete-scute complex protein T8

1

20

Small-scale

0.656

High

560164

ESM5
Enhancer of split m5 protein

1

16

Small-scale

0.656

High

878205

ATO
Protein atonal

1

20

Small-scale

0.656

High

1028539

ESMB
Enhancer of split mbeta protein

1

18

Small-scale

0.656

High

1028540

ESMC
Enhancer of split mgamma protein

1

18

Small-scale

0.656

High

1028541

ESMD
Enhancer of split mdelta protein

1

17

Small-scale

0.656

High

1028542

Q24090
GH08712p

2

1

High-throughput

0.571

High

1028543

HR78
Nuclear hormone receptor HR78

1

20

High-throughput

0.541

High

1028545

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

5

High-throughput

0.541

High

1028546

Q9VDQ3
Identity crisis

1

1

High-throughput

0.508

High

119520

M9NHC5
Uncharacterized protein, isoform C

1

2

High-throughput

0.479

High

1028544

Q8I0J6
Degringolade, isoform B

1

10

Small-scale

0.479

High

1028551

Q9W3A1
Uncharacterized protein, isoform A

1

3

High-throughput

0.464

High

263516

MK38B
Mitogen-activated protein kinase p38b

1

1

High-throughput

0.445

High

1028550

Q9VWG1
LD37169p

1

2

High-throughput

0.445

High

118300

M9ND06
Replication in mitochondria 2, isoform C

1

1

High-throughput

0.439

High

1028547

Q9VKI8
GH03305p

1

3

High-throughput

0.439

High

1028548

RIM2
Mitochondrial carrier protein Rim2

1

1

High-throughput

0.417

High

732226

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.265

Low

715085

CLH
Clathrin heavy chain

1

0

High-throughput

0.232

Low

1028549

CLC
Clathrin light chain

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025