Protein: ESMC
Enhancer of split mgamma protein (E(spl)mgamma) (Split locus enhancer protein mB)

Gene: ESMC, E(spl)mgamma-HLH
Organism: Drosophila melanogaster
Interactions: 27
UniProt ID: Q01070

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0002052 - positive regulation of neuroblast proliferation
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

518457

AST5
Achaete-scute complex protein T5

3

20

Small-scale

0.843

High

518491

AST4
Achaete-scute complex protein T4

3

20

Small-scale

0.832

High

542909

DA
Protein daughterless

2

8

Small-scale

0.768

High

560209

ESM8
Enhancer of split m8 protein

2

16

Small-scale

0.768

High

652967

VND
Homeobox protein vnd

1

7

High-throughput

0.698

High

1028564

HEY
Hairy/enhancer-of-split related with YRPW motif protein

1

18

High-throughput

0.698

High

486735

AST8
Achaete-scute complex protein T8

1

20

Small-scale

0.656

High

560166

ESM5
Enhancer of split m5 protein

1

16

Small-scale

0.656

High

560179

ESM7
Enhancer of split m7 protein

1

18

Small-scale

0.656

High

1028540

ESM3
Enhancer of split m3 protein

1

18

Small-scale

0.656

High

1028553

ESMB
Enhancer of split mbeta protein

1

19

Small-scale

0.656

High

1028558

ESMC
Enhancer of split mgamma protein

1

18

Small-scale

0.656

High

1028559

ESMD
Enhancer of split mdelta protein

1

18

Small-scale

0.656

High

594685

GROU
Protein groucho

3

20

Small-scale

0.648

High

1028563

Q7JZ51
Insensible, isoform A

3

3

Small-scale

0.646

High

1028560

Q0IGU0
IP21556p

1

7

High-throughput

0.637

High

1014298

UBX
Homeotic protein ultrabithorax

1

6

High-throughput

0.621

High

1028561

DPN
Protein deadpan

1

19

Small-scale

0.618

High

638295

SINA
E3 ubiquitin-protein ligase sina

2

1

High-throughput

0.594

High

1028569

PSA6
Proteasome subunit alpha type-6

2

1

High-throughput

0.594

High

1028567

Q9VFL3
FI08014p

2

1

High-throughput

0.542

High

715243

ETS3
DNA-binding protein D-ETS-3

1

1

High-throughput

0.541

High

1028562

Q4V5A5
IP14661p

1

1

High-throughput

0.541

High

1028566

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

5

High-throughput

0.541

High

1028565

Q8I0J6
Degringolade, isoform B

1

10

Small-scale

0.479

High

1028568

Q9VWT5
X-ray repair cross complementing 2

1

0

High-throughput

0.282

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025