Protein: ESMD
Enhancer of split mdelta protein (E(spl)mdelta) (HLH-mdelta) (Split locus enhancer protein mC)

Gene: ESMD, E(spl)mdelta-HLH
Organism: Drosophila melanogaster
Interactions: 39
UniProt ID: Q01071

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0007219 - Notch signaling pathway
GO:0007525 - somatic muscle development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

594686

GROU
Protein groucho

6

20

Small-scale

0.734

High

560167

ESM5
Enhancer of split m5 protein

2

16

Small-scale

0.723

High

1028570

ESMD
Enhancer of split mdelta protein

2

19

Small-scale

0.723

High

1028582

LASP1
LIM and SH3 domain protein Lasp

2

1

High-throughput

0.686

High

560180

ESM7
Enhancer of split m7 protein

1

17

Small-scale

0.656

High

560210

ESM8
Enhancer of split m8 protein

1

16

Small-scale

0.656

High

1028541

ESM3
Enhancer of split m3 protein

1

17

Small-scale

0.656

High

1028554

ESMB
Enhancer of split mbeta protein

1

19

Small-scale

0.656

High

1028559

ESMC
Enhancer of split mgamma protein

1

18

Small-scale

0.656

High

1014299

UBX
Homeotic protein ultrabithorax

1

6

High-throughput

0.621

High

1028576

Q7JZ51
Insensible, isoform A

2

3

High-throughput

0.594

High

1028592

Q9VRQ6
Uncharacterized protein, isoform A

2

0

High-throughput

0.569

High

1028571

HR78
Nuclear hormone receptor HR78

1

20

High-throughput

0.541

High

1028577

GLIS2
Zinc finger protein GLIS2 homolog

1

1

High-throughput

0.541

High

1028585

Q962I0
LD47926p

1

1

High-throughput

0.541

High

1028590

Q9VM77
FI20031p1

1

1

High-throughput

0.541

High

235204

HTH
Homeobox protein homothorax

1

0

High-throughput

0.518

High

1028574

E2F1
Transcription factor E2f1

1

0

High-throughput

0.518

High

1028579

Q7KT79
C2H2-type domain-containing protein

1

0

High-throughput

0.518

High

1028580

CHN
Protein charlatan

1

0

High-throughput

0.518

High

234463

CTBP
C-terminal-binding protein

1

3

Small-scale

0.508

High

1028575

Q59DN8
Shaven, isoform F

1

1

High-throughput

0.481

High

1028581

Q8I0J6
Degringolade, isoform B

1

10

Small-scale

0.479

High

1028578

Q7KND8
FI09619p

1

3

High-throughput

0.464

High

1028583

Q8MSM9
AT18730p

1

1

High-throughput

0.464

High

195197

O16117
Shaven, isoform A

1

1

High-throughput

0.457

High

1028572

Q24216
Cyclin-dependent kinase 7

1

1

High-throughput

0.445

High

1028593

Q9VXR9
FI03680p

1

1

High-throughput

0.439

High

1028584

Q961V9
GH03273p

1

1

High-throughput

0.417

High

1028573

CDC37
Hsp90 co-chaperone Cdc37

3

0

High-throughput

0.340

High

458839

SRYA
Serendipity locus protein alpha

2

0

High-throughput

0.310

High

1028587

Q9VHV6
RE31520p

2

0

High-throughput

0.310

High

1028591

Q9VMY2
RE15880p

2

0

High-throughput

0.310

High

1028586

Q9V3G9
AT18705p

1

0

High-throughput

0.265

Low

1028588

PAK
Serine/threonine-protein kinase Pak

1

0

High-throughput

0.265

Low

1028594

Q9VZV8
LD46404p

1

0

High-throughput

0.265

Low

1028595

Q9XZ15
LD17368p

1

0

High-throughput

0.265

Low

1028589

Q9VM19
Trehalose 6-phosphate phosphatase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025