Protein: KLHL8
Kelch-like protein 8

Gene: KLHL8
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q9P2G9

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
GO:0031463 - Cul3-RING ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1042720

CUL3
Cullin-3

9

20

Small-scale

0.970

High

177611

SIGL5
Sialic acid-binding Ig-like lectin 5

2

3

High-throughput

0.726

High

1235383

KCD17
BTB/POZ domain-containing protein KCTD17

1

3

High-throughput

0.691

High

911985

RUXF
Small nuclear ribonucleoprotein F

3

0

High-throughput

0.646

High

442562

RU17
U1 small nuclear ribonucleoprotein 70 kDa

2

2

High-throughput

0.628

High

1271207

RBP56
TATA-binding protein-associated factor 2N

2

5

High-throughput

0.628

High

1327796

RGAP1
Rac GTPase-activating protein 1

2

1

High-throughput

0.628

High

1184998

CSN6
COP9 signalosome complex subunit 6

2

9

High-throughput

0.621

High

800952

MK09
Mitogen-activated protein kinase 9

2

2

High-throughput

0.606

High

448838

RU1C
U1 small nuclear ribonucleoprotein C

2

0

High-throughput

0.602

High

1347574

GEMI8
Gem-associated protein 8

2

0

High-throughput

0.602

High

518946

RLBP1
Retinaldehyde-binding protein 1

2

0

High-throughput

0.580

High

826926

TCPG
T-complex protein 1 subunit gamma

2

3

High-throughput

0.574

High

1306718

TCPH
T-complex protein 1 subunit eta

2

3

High-throughput

0.574

High

1326971

UBA5
Ubiquitin-like modifier-activating enzyme 5

2

1

High-throughput

0.574

High

503171

PNMT
Phenylethanolamine N-methyltransferase

2

2

High-throughput

0.553

High

716590

CAH8
Carbonic anhydrase-related protein

2

1

High-throughput

0.553

High

441385

RU2B
U2 small nuclear ribonucleoprotein B''

1

1

High-throughput

0.536

High

446822

SNRPA
U1 small nuclear ribonucleoprotein A

1

1

High-throughput

0.536

High

453927

RU2A
U2 small nuclear ribonucleoprotein A'

1

6

High-throughput

0.536

High

897321

CSN2
COP9 signalosome complex subunit 2

1

17

High-throughput

0.536

High

912120

RUXG
Small nuclear ribonucleoprotein G

1

4

High-throughput

0.536

High

921453

RBX1
E3 ubiquitin-protein ligase RBX1

1

7

High-throughput

0.536

High

1024231

CSN1
COP9 signalosome complex subunit 1

1

13

High-throughput

0.536

High

1216459

RBM45
RNA-binding protein 45

1

1

High-throughput

0.536

High

1272661

CSN5
COP9 signalosome complex subunit 5

1

11

High-throughput

0.536

High

1292397

DCNL1
DCN1-like protein 1

1

10

High-throughput

0.536

High

1305355

CSN8
COP9 signalosome complex subunit 8

1

2

High-throughput

0.536

High

1344043

PDLI7
PDZ and LIM domain protein 7

1

4

High-throughput

0.536

High

1348326

SPHK1
Sphingosine kinase 1

1

1

High-throughput

0.536

High

1350341

CSN3
COP9 signalosome complex subunit 3

1

15

High-throughput

0.536

High

353217

LV657
Immunoglobulin lambda variable 6-57

1

3

High-throughput

0.514

High

1329453

PDCL3
Phosducin-like protein 3

1

0

High-throughput

0.513

High

1350340

CGBP1
CGG triplet repeat-binding protein 1

1

0

High-throughput

0.513

High

1044910

RAPSN
43 kDa receptor-associated protein of the synapse

1

3

Small-scale

0.512

High

868780

ATX1
Ataxin-1

1

4

High-throughput

0.508

High

1273939

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

8

High-throughput

0.508

High

1350339

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.493

High

147362

DPYL4
Dihydropyrimidinase-related protein 4

1

1

High-throughput

0.489

High

243649

DNJA2
DnaJ homolog subfamily A member 2

1

3

High-throughput

0.489

High

534273

YJU2B
Probable splicing factor YJU2B

1

2

High-throughput

0.489

High

623682

IBP5
Insulin-like growth factor-binding protein 5

1

3

High-throughput

0.489

High

626328

CO8A2
Collagen alpha-2(VIII) chain

1

4

High-throughput

0.489

High

821446

TCPE
T-complex protein 1 subunit epsilon

1

3

High-throughput

0.489

High

943522

TCPB
T-complex protein 1 subunit beta

1

5

High-throughput

0.489

High

1110309

SP6
Transcription factor Sp6

1

4

High-throughput

0.489

High

1121808

ANR39
Ankyrin repeat domain-containing protein 39

1

2

High-throughput

0.489

High

1176305

ATS13
A disintegrin and metalloproteinase with thrombospondin motifs 13

1

1

High-throughput

0.489

High

1229774

ZN444
Zinc finger protein 444

1

5

High-throughput

0.489

High

1292806

XAGE2
X antigen family member 2

1

1

High-throughput

0.489

High

1304284

GA2L1
GAS2-like protein 1

1

2

High-throughput

0.489

High

1315233

RFIP5
Rab11 family-interacting protein 5

1

1

High-throughput

0.489

High

1315251

5NT1A
Cytosolic 5'-nucleotidase 1A

1

1

High-throughput

0.489

High

1318268

GSX2
GS homeobox 2

1

1

High-throughput

0.489

High

1350342

NEUR2
Sialidase-2

1

2

High-throughput

0.489

High

750510

COIL
Coilin

1

0

High-throughput

0.486

High

718265

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.479

High

1036964

SQSTM
Sequestosome-1

1

5

High-throughput

0.479

High

1085702

HIF1A
Hypoxia-inducible factor 1-alpha

1

3

Small-scale

0.479

High

573513

TCPA
T-complex protein 1 subunit alpha

1

3

High-throughput

0.470

High

1153095

Q6IPC0
Protein phosphatase 1F

1

1

High-throughput

0.470

High

829471

PPM1F
Protein phosphatase 1F

1

1

High-throughput

0.439

High

483639

CSH2
Chorionic somatomammotropin hormone 2

1

1

High-throughput

0.437

High

483620

CSH1
Chorionic somatomammotropin hormone 1

1

1

High-throughput

0.407

High

738936

PEDF
Pigment epithelium-derived factor

2

0

High-throughput

0.328

High

1293368

CC120
Coiled-coil domain-containing protein 120

2

0

High-throughput

0.328

High

815041

LEG7
Galectin-7

2

0

High-throughput

0.318

High

120103

ST2B1
Sulfotransferase 2B1

2

0

High-throughput

0.316

High

1189154

ARMC9
LisH domain-containing protein ARMC9

2

0

High-throughput

0.316

High

1240384

P5I13
Tumor protein p53-inducible protein 13

2

0

High-throughput

0.316

High

1316028

TX101
Testis-expressed protein 101

2

0

High-throughput

0.316

High

208304

DCX
Neuronal migration protein doublecortin

1

0

High-throughput

0.279

Low

265482

PAGE1
P antigen family member 1

1

0

High-throughput

0.279

Low

1125966

TCAL5
Transcription elongation factor A protein-like 5

1

0

High-throughput

0.279

Low

1203389

PRSR2
Proline and serine-rich protein 2

1

0

High-throughput

0.279

Low

1273134

GCDH
Glutaryl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1297561

MAGBA
Melanoma-associated antigen B10

1

0

High-throughput

0.279

Low

1335810

WFDC1
WAP four-disulfide core domain protein 1

1

0

High-throughput

0.279

Low

738095

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024