Protein: IMD
Protein immune deficiency

Gene: IMD
Organism: Drosophila melanogaster
Interactions: 119
UniProt ID: Q7K4Z4

Gene Ontology (top 5):
GO:0002230 - positive regulation of defense response to virus by host
GO:0002803 - positive regulation of antibacterial peptide production
GO:0005829 - cytosol
GO:0006955 - immune response
GO:0006959 - humoral immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1266713

FADD
Fas-associated death domain protein

6

0

Small-scale

0.890

High

1266696

IMD
Protein immune deficiency

1

0

Small-scale

0.674

High

1266710

PGPLC
Peptidoglycan-recognition protein LC

3

1

Small-scale

0.640

High

1266755

Q9W2E6
Poor Imd response upon knock-in, isoform A

3

0

Small-scale

0.613

High

198146

GBLP
Small ribosomal subunit protein RACK1

2

0

High-throughput

0.575

High

559803

EF2
Eukaryotic translation elongation factor 2

2

0

High-throughput

0.575

High

1266704

CASP8
Caspase-8

2

0

Small-scale

0.569

High

1173312

DIAP2
Death-associated inhibitor of apoptosis 2

2

0

Small-scale

0.559

High

54136

A1Z893
1-Cys peroxiredoxin

1

2

High-throughput

0.481

High

1266716

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

Small-scale

0.480

High

198045

PRS8
26S proteasome regulatory subunit 8

1

1

Small-scale

0.479

High

1266697

Q7KMQ0
26S proteasome regulatory subunit 7

1

1

High-throughput

0.479

High

1266715

PRDX2
Peroxiredoxin 2

1

2

High-throughput

0.479

High

1266746

PGPLE
Peptidoglycan-recognition protein LE

1

1

Small-scale

0.479

High

1266702

Q8I0N3
RE31819p

1

1

High-throughput

0.464

High

1266714

Q9V3G9
AT18705p

1

1

High-throughput

0.464

High

1266744

Q9VW23
Male sterile

1

1

High-throughput

0.464

High

415065

CYC1
Cytochrome c-1

1

0

High-throughput

0.458

High

538244

HSP7D
Heat shock 70 kDa protein cognate 4

1

0

High-throughput

0.458

High

604337

CATA
Catalase

1

0

High-throughput

0.458

High

633065

NCD
Protein claret segregational

1

0

High-throughput

0.458

High

852494

CADF
Cofilin/actin-depolymerizing factor homolog

1

0

High-throughput

0.458

High

938881

FAF
Probable ubiquitin carboxyl-terminal hydrolase FAF

1

0

Small-scale

0.458

High

1266709

BCL9
Protein BCL9 homolog

1

0

High-throughput

0.458

High

1266711

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.458

High

1266726

VRET
Protein vreteno

1

0

High-throughput

0.458

High

1266732

Q9VHL2
T-complex protein 1 subunit eta

1

0

High-throughput

0.458

High

1266733

SMD2
Probable small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

1266735

SOYB
Putative ATP-dependent RNA helicase SoYb

1

0

High-throughput

0.458

High

1266741

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

Small-scale

0.458

High

1266742

FRL
Formin-like protein

1

0

High-throughput

0.458

High

1266762

RHGF
Rho GTPase-activating protein Graf

1

0

High-throughput

0.458

High

54011

A1Z892
1-Cys peroxiredoxin

1

2

High-throughput

0.457

High

1266698

Q7KTD2
SR family splicing factor SC35, isoform A

1

1

High-throughput

0.439

High

1266724

Q9VBE0
TweedleB

1

1

High-throughput

0.439

High

119832

HAKAI
E3 ubiquitin-protein ligase Hakai

1

0

High-throughput

0.438

High

53053

A1Z7K2
FI03455p

1

1

High-throughput

0.437

High

146115

CH60A
Heat shock protein 60A

1

1

High-throughput

0.437

High

444082

TBA1
Tubulin alpha-1 chain

1

2

High-throughput

0.437

High

444119

TBA2
Tubulin alpha-2 chain

1

2

High-throughput

0.437

High

444143

TBA3
Tubulin alpha-3 chain

1

2

High-throughput

0.437

High

715357

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.437

High

715397

HSP7E
Heat shock 70 kDa protein cognate 5

1

2

High-throughput

0.437

High

856463

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.437

High

875219

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.437

High

1265771

Q7K3J0
T-complex protein 1 subunit theta

1

1

High-throughput

0.437

High

1266701

LIG
Protein lingerer

1

1

High-throughput

0.437

High

1266703

SLE
Protein slender lobes

1

1

High-throughput

0.437

High

1266712

NH2L1
NHP2-like protein 1 homolog

1

1

High-throughput

0.437

High

1266727

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

1

High-throughput

0.437

High

1266729

SLEL
Slender lobes-like protein

1

1

High-throughput

0.437

High

1266737

CH60C
60 kDa heat shock protein homolog 2, mitochondrial

1

1

High-throughput

0.437

High

1266759

Q9W392
T-complex protein 1 subunit beta

1

1

High-throughput

0.437

High

1266761

EAF3
NuA4 complex subunit EAF3 homolog

1

1

High-throughput

0.437

High

1266717

Q9V3T8
LD32469p

1

1

High-throughput

0.417

High

938908

RS20
Small ribosomal subunit protein uS10

2

0

High-throughput

0.313

High

145781

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

0

High-throughput

0.265

Low

912366

UBC84
Ubiquitin-conjugating enzyme E2-18 kDa

1

0

High-throughput

0.265

Low

1265122

Q7K264
LD16826p

1

0

High-throughput

0.265

Low

1266736

Q9VMC3
LD35051p

1

0

High-throughput

0.265

Low

1266743

ROGDI
Protein rogdi

1

0

High-throughput

0.265

Low

1266749

Q9W0C3
GH11843p

1

0

High-throughput

0.265

Low

1266760

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.265

Low

57786

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.249

Low

120498

M9PD90
Discs large 5, isoform D

1

0

High-throughput

0.249

Low

197779

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.249

Low

234477

CTBP
C-terminal-binding protein

1

0

High-throughput

0.249

Low

234698

O46048
EG:133E12.4 protein

1

0

High-throughput

0.249

Low

583637

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.249

Low

652041

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

0

High-throughput

0.249

Low

654857

MA205
205 kDa microtubule-associated protein

1

0

High-throughput

0.249

Low

770951

ATPA
ATP synthase subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

891977

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.249

Low

898328

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.249

Low

963849

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.249

Low

1013228

STIM
Stromal interaction molecule homolog

1

0

High-throughput

0.249

Low

1019545

MIC60
MICOS complex subunit Mic60

1

0

High-throughput

0.249

Low

1055705

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

1070937

Q0KI85
Sidestep VI, isoform B

1

0

High-throughput

0.249

Low

1173531

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.249

Low

1174355

CP190
Centrosome-associated zinc finger protein Cp190

1

0

High-throughput

0.249

Low

1174586

TBB1
Tubulin beta-1 chain

1

0

High-throughput

0.249

Low

1175938

ADT
ADP,ATP carrier protein

1

0

High-throughput

0.249

Low

1260738

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

1263883

Q7K012
Brahma associated protein 55kD

1

0

High-throughput

0.249

Low

1266335

DGT5
Augmin complex subunit dgt5

1

0

High-throughput

0.249

Low

1266699

Q7KTV5
Nopp140, isoform B

1

0

High-throughput

0.249

Low

1266700

Q86BM5
A kinase anchor protein 200, isoform D

1

0

High-throughput

0.249

Low

1266705

LVA
Protein lava lamp

1

0

High-throughput

0.249

Low

1266706

Q8SYU0
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.249

Low

1266707

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

0

High-throughput

0.249

Low

1266708

CATL1
Cathepsin L1

1

0

High-throughput

0.249

Low

1266718

Q9V406
Activator protein 4

1

0

High-throughput

0.249

Low

1266719

PDIA6
Protein disulfide-isomerase A6 homolog

1

0

High-throughput

0.249

Low

1266720

HCF
Host cell factor

1

0

High-throughput

0.249

Low

1266721

ANLN
Anillin

1

0

High-throughput

0.249

Low

1266722

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

High-throughput

0.249

Low

1266723

S39AD
Zinc transporter ZIP13 homolog

1

0

High-throughput

0.249

Low

1266725

Q9VBU9
40S ribosomal protein S27

1

0

High-throughput

0.249

Low

1266728

MBDR2
Protein MBD-R2

1

0

High-throughput

0.249

Low

1266730

RUVB1
RuvB-like helicase 1

1

0

High-throughput

0.249

Low

1266731

Q9VHH8
Beag

1

0

High-throughput

0.249

Low

1266734

Q9VJD1
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low

1266738

Q9VP57
LD15904p

1

0

High-throughput

0.249

Low

1266739

Q9VPU7
Arouser, isoform C

1

0

High-throughput

0.249

Low

1266740

Q9VRL8
Blanks

1

0

High-throughput

0.249

Low

1266745

Q9VWP5
Hat-trick, isoform D

1

0

High-throughput

0.249

Low

1266747

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

0

High-throughput

0.249

Low

1266748

Q9VZF2
LD05244p

1

0

High-throughput

0.249

Low

1266750

Q9W1B9
Large ribosomal subunit protein uL11

1

0

High-throughput

0.249

Low

1266751

Q9W1H5
Decapping protein 1, isoform A

1

0

High-throughput

0.249

Low

1266752

Q9W1I8
LD03592p

1

0

High-throughput

0.249

Low

1266753

NU214
Nuclear pore complex protein Nup214

1

0

High-throughput

0.249

Low

1266754

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.249

Low

1266756

SGF29
SAGA-associated factor 29kDa

1

0

High-throughput

0.249

Low

1266758

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.249

Low

1266763

X2JLM6
Ubiquitin carboxyl-terminal hydrolase

1

0

Small-scale

0.249

Low

1266757

Q9W2L2
LD27118p

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025