Protein: PLPP2
Phospholipid phosphatase 2 (EC 3.1.3.-) (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 2) (PAP2-gamma) (PAP2-G) (Phosphatidate phosphohydrolase type 2c) (Phosphatidic acid phosphatase 2c) (PAP-2c) (PAP2c)

Gene: PLPP2
Organism: Homo sapiens
Interactions: 23
UniProt ID: O43688

Gene Ontology (top 5):
GO:0005769 - early endosome
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0005901 - caveola

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

154519

PLPP1
Phospholipid phosphatase 1

2

11

Small-scale

0.789

High

154544

PLPP3
Phospholipid phosphatase 3

2

11

Small-scale

0.789

High

224434

PLPP2
Phospholipid phosphatase 2

1

11

Small-scale

0.618

High

224444

VSTM1
V-set and transmembrane domain-containing protein 1

2

1

High-throughput

0.606

High

224440

NSG1
Neuronal vesicle trafficking-associated protein 1

2

0

High-throughput

0.580

High

224448

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.580

High

224449

TR1L1
Translocating chain-associated membrane protein 1-like 1

2

0

High-throughput

0.580

High

224436

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

224441

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.541

High

224437

LEG3
Galectin-3

1

2

High-throughput

0.536

High

224439

HNF4A
Hepatocyte nuclear factor 4-alpha

1

1

High-throughput

0.523

High

224445

NT2NA
Notch homolog 2 N-terminal-like protein A

1

3

High-throughput

0.523

High

224451

RM44
Large ribosomal subunit protein mL44

1

0

High-throughput

0.518

High

224450

IGDC4
Immunoglobulin superfamily DCC subclass member 4

1

0

High-throughput

0.513

High

224452

PCDA8
Protocadherin alpha-8

1

0

High-throughput

0.513

High

125091

LEG9
Galectin-9

1

2

High-throughput

0.489

High

224435

NPT2B
Sodium-dependent phosphate transport protein 2B

1

2

High-throughput

0.445

High

224438

MLH1
DNA mismatch repair protein Mlh1

1

0

Small-scale

0.438

High

224442

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High

224443

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

0

High-throughput

0.279

Low

224446

RABEK
Rab9 effector protein with kelch motifs

1

0

High-throughput

0.249

Low

224447

TM192
Transmembrane protein 192

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025