Protein: K1C17
Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)

Gene: K1C17, KRT17
Organism: Homo sapiens
Interactions: 237
UniProt ID: Q04695

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0005198 - structural molecule activity
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0030307 - positive regulation of cell growth

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

409054

K2C8
Keratin, type II cytoskeletal 8

3

20

Small-scale

0.843

High

359482

K2C6A
Keratin, type II cytoskeletal 6A

2

20

High-throughput

0.785

High

980257

K2C72
Keratin, type II cytoskeletal 72

2

20

Small-scale

0.757

High

443468

VIME
Vimentin

2

20

High-throughput

0.754

High

980281

K2C1B
Keratin, type II cytoskeletal 1b

1

20

High-throughput

0.665

High

359335

K1C14
Keratin, type I cytoskeletal 14

1

20

High-throughput

0.618

High

380597

K2C1
Keratin, type II cytoskeletal 1

1

20

High-throughput

0.618

High

408784

K1C18
Keratin, type I cytoskeletal 18

1

20

High-throughput

0.618

High

444354

K1C19
Keratin, type I cytoskeletal 19

1

20

High-throughput

0.618

High

444534

K2C7
Keratin, type II cytoskeletal 7

1

20

High-throughput

0.618

High

445035

K1C16
Keratin, type I cytoskeletal 16

1

20

High-throughput

0.618

High

531352

K1C10
Keratin, type I cytoskeletal 10

1

19

High-throughput

0.618

High

531464

K1C13
Keratin, type I cytoskeletal 13

1

20

High-throughput

0.618

High

531555

K2C5
Keratin, type II cytoskeletal 5

1

20

High-throughput

0.618

High

724064

K1C9
Keratin, type I cytoskeletal 9

1

20

High-throughput

0.618

High

729070

K22E
Keratin, type II cytoskeletal 2 epidermal

1

20

High-throughput

0.618

High

821648

K2C6C
Keratin, type II cytoskeletal 6C

1

20

High-throughput

0.618

High

980271

K2C79
Keratin, type II cytoskeletal 79

1

20

High-throughput

0.618

High

980280

K1C27
Keratin, type I cytoskeletal 27

1

20

High-throughput

0.618

High

980286

K2C78
Keratin, type II cytoskeletal 78

1

20

High-throughput

0.618

High

924493

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.611

High

626105

APC
Adenomatous polyposis coli protein

2

8

High-throughput

0.608

High

255704

OBSL1
Obscurin-like protein 1

2

9

High-throughput

0.584

High

453303

ROA1
Heterogeneous nuclear ribonucleoprotein A1

2

14

High-throughput

0.584

High

644011

EF1G
Elongation factor 1-gamma

2

1

Small-scale

0.584

High

980283

TRI69
E3 ubiquitin-protein ligase TRIM69

1

11

High-throughput

0.573

High

529011

CFTR
Cystic fibrosis transmembrane conductance regulator

2

20

Small-scale

0.571

High

926952

1433Z
14-3-3 protein zeta/delta

2

17

Small-scale

0.571

High

310933

SNAPN
SNARE-associated protein Snapin

1

7

High-throughput

0.541

High

980302

CSN5
COP9 signalosome complex subunit 5

1

18

High-throughput

0.536

High

980262

CC85B
Coiled-coil domain-containing protein 85B

1

5

High-throughput

0.532

High

296295

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

11

High-throughput

0.515

High

456554

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

10

High-throughput

0.515

High

980314

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

1

High-throughput

0.515

High

349263

RASH
GTPase HRas

1

2

Small-scale

0.501

High

980285

ZDH17
Palmitoyltransferase ZDHHC17

1

2

High-throughput

0.494

High

980258

FL2D
Pre-mRNA-splicing regulator WTAP

1

8

High-throughput

0.489

High

980290

NETO2
Neuropilin and tolloid-like protein 2

1

1

High-throughput

0.489

High

129281

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.479

High

133991

DDX3X
ATP-dependent RNA helicase DDX3X

1

7

Small-scale

0.479

High

164607

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

10

High-throughput

0.479

High

165970

PER2
Period circadian protein homolog 2

1

1

Small-scale

0.479

High

176435

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

11

High-throughput

0.479

High

197283

SERA
D-3-phosphoglycerate dehydrogenase

1

7

Small-scale

0.479

High

201586

MCA3
Eukaryotic translation elongation factor 1 epsilon-1

1

2

High-throughput

0.479

High

227231

PRKN
E3 ubiquitin-protein ligase parkin

1

15

High-throughput

0.479

High

282631

RNF8
E3 ubiquitin-protein ligase RNF8

1

17

High-throughput

0.479

High

325699

LATS1
Serine/threonine-protein kinase LATS1

1

11

High-throughput

0.479

High

386576

P53
Cellular tumor antigen p53

1

8

Small-scale

0.479

High

388392

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.479

High

396722

S10A8
Protein S100-A8

1

3

High-throughput

0.479

High

416410

S10A9
Protein S100-A9

1

3

High-throughput

0.479

High

431761

HS90A
Heat shock protein HSP 90-alpha

1

1

High-throughput

0.479

High

432665

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

3

High-throughput

0.479

High

433140

LAMB1
Laminin subunit beta-1

1

1

High-throughput

0.479

High

438093

HS90B
Heat shock protein HSP 90-beta

1

1

High-throughput

0.479

High

450848

F16P1
Fructose-1,6-bisphosphatase 1

1

6

High-throughput

0.479

High

475002

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

3

High-throughput

0.479

High

499700

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

502001

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.479

High

503941

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

531127

EF2
Elongation factor 2

1

9

High-throughput

0.479

High

542290

PLAK
Junction plakoglobin

1

2

High-throughput

0.479

High

551676

DESP
Desmoplakin

1

20

High-throughput

0.479

High

584934

RO52
E3 ubiquitin-protein ligase TRIM21

1

18

High-throughput

0.479

High

610361

CBL
E3 ubiquitin-protein ligase CBL

1

11

High-throughput

0.479

High

618061

COF1
Cofilin-1

1

4

High-throughput

0.479

High

646819

1433T
14-3-3 protein theta

1

17

High-throughput

0.479

High

653905

PDE4A
3',5'-cyclic-AMP phosphodiesterase 4A

1

1

High-throughput

0.479

High

666076

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.479

High

669341

EF1D
Elongation factor 1-delta

1

2

High-throughput

0.479

High

725143

MYH10
Myosin-10

1

3

High-throughput

0.479

High

776656

STAT3
Signal transducer and activator of transcription 3

1

1

High-throughput

0.479

High

780684

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

2

High-throughput

0.479

High

787899

EPS15
Epidermal growth factor receptor substrate 15

1

20

High-throughput

0.479

High

802570

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

826625

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.479

High

842328

PPT1
Palmitoyl-protein thioesterase 1

1

1

High-throughput

0.479

High

874849

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.479

High

893002

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

901135

RND3
Rho-related GTP-binding protein RhoE

1

6

High-throughput

0.479

High

908412

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

13

High-throughput

0.479

High

918305

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

929408

RACK1
Small ribosomal subunit protein RACK1

1

6

High-throughput

0.479

High

932662

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.479

High

933764

TBB4B
Tubulin beta-4B chain

1

1

High-throughput

0.479

High

950941

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.479

High

952287

H33
Histone H3.3

1

1

High-throughput

0.479

High

962025

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

3

High-throughput

0.479

High

970757

DSG1
Desmoglein-1

1

2

High-throughput

0.479

High

974058

DYST
Dystonin

1

20

High-throughput

0.479

High

980245

DSC1
Desmocollin-1

1

1

High-throughput

0.479

High

980253

DPYL1
Dihydropyrimidinase-related protein 1

1

2

High-throughput

0.479

High

980254

DPYL3
Dihydropyrimidinase-related protein 3

1

2

High-throughput

0.479

High

980256

CUL7
Cullin-7

1

6

High-throughput

0.479

High

980259

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

9

High-throughput

0.479

High

980261

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

16

High-throughput

0.479

High

980264

DPYL2
Dihydropyrimidinase-related protein 2

1

2

High-throughput

0.479

High

980265

LARP7
La-related protein 7

1

15

High-throughput

0.479

High

980267

FILA2
Filaggrin-2

1

4

High-throughput

0.479

High

980272

VIR
Protein virilizer homolog

1

5

High-throughput

0.479

High

980274

RICTR
Rapamycin-insensitive companion of mTOR

1

6

High-throughput

0.479

High

980275

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

7

High-throughput

0.479

High

980276

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

980277

CRACD
Capping protein-inhibiting regulator of actin dynamics

1

18

High-throughput

0.479

High

980282

ZN598
E3 ubiquitin-protein ligase ZNF598

1

2

High-throughput

0.479

High

980284

HORN
Hornerin

1

3

High-throughput

0.479

High

980292

TTL11
Tubulin polyglutamylase TTLL11

1

2

High-throughput

0.479

High

980293

RBCC1
RB1-inducible coiled-coil protein 1

1

20

High-throughput

0.479

High

980299

RND1
Rho-related GTP-binding protein Rho6

1

5

High-throughput

0.479

High

980305

FUBP2
Far upstream element-binding protein 2

1

3

High-throughput

0.479

High

980307

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

8

Small-scale

0.479

High

980308

AP2M1
AP-2 complex subunit mu

1

8

High-throughput

0.479

High

980316

FACD2
Fanconi anemia group D2 protein

1

9

High-throughput

0.479

High

980321

RN208
RING finger protein 208

1

20

Small-scale

0.479

High

980322

GAN
Gigaxonin

1

14

High-throughput

0.479

High

980324

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

15

High-throughput

0.479

High

980325

ANLN
Anillin

1

12

High-throughput

0.479

High

980333

HDAC6
Histone deacetylase 6

1

20

High-throughput

0.479

High

980334

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

980335

TES
Testin

1

3

High-throughput

0.479

High

980336

FZR1
Fizzy-related protein homolog

1

16

High-throughput

0.479

High

980298

ARAP2
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

1

8

High-throughput

0.470

High

232115

KDM1A
Lysine-specific histone demethylase 1A

1

10

High-throughput

0.464

High

130052

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.458

High

381942

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.458

High

396225

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

417241

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

427528

ANXA2
Annexin A2

1

0

High-throughput

0.458

High

430145

PROF1
Profilin-1

1

0

High-throughput

0.458

High

445375

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.458

High

506231

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.458

High

519174

KCRB
Creatine kinase B-type

1

0

High-throughput

0.458

High

537880

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.458

High

550733

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

582242

NUCL
Nucleolin

1

0

High-throughput

0.458

High

607058

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

0

High-throughput

0.458

High

616268

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

671212

RL12
Large ribosomal subunit protein uL11

1

0

High-throughput

0.458

High

683068

CASPE
Caspase-14

1

0

High-throughput

0.458

High

759626

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

825928

FAS
Fatty acid synthase

1

0

High-throughput

0.458

High

842465

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.458

High

907860

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.458

High

914932

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.458

High

920437

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.458

High

932961

ACTS
Actin, alpha skeletal muscle

1

0

High-throughput

0.458

High

960755

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.458

High

980244

PRDX1
Peroxiredoxin-1

1

0

High-throughput

0.458

High

980260

SYK
Lysine--tRNA ligase

1

0

High-throughput

0.458

High

980313

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.458

High

980327

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.458

High

980329

RAB6B
Ras-related protein Rab-6B

1

0

High-throughput

0.458

High

980330

SPAT7
Spermatogenesis-associated protein 7

1

0

High-throughput

0.458

High

980328

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

170638

AXIN1
Axin-1

1

1

High-throughput

0.445

High

319805

HERC2
E3 ubiquitin-protein ligase HERC2

1

3

High-throughput

0.445

High

338309

EGFR
Epidermal growth factor receptor

1

11

Small-scale

0.445

High

496892

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

724787

MYH9
Myosin-9

1

3

High-throughput

0.445

High

980248

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

3

High-throughput

0.445

High

980269

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.445

High

980278

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.445

High

980320

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

165843

KDM6B
Lysine-specific demethylase 6B

1

3

Small-scale

0.437

High

225614

PCDH7
Protocadherin-7

1

2

High-throughput

0.437

High

303184

HEXI1
Protein HEXIM1

1

20

High-throughput

0.437

High

363769

ALBU
Albumin

1

7

High-throughput

0.437

High

379313

MYCN
N-myc proto-oncogene protein

1

13

High-throughput

0.437

High

397349

ADT2
ADP/ATP translocase 2

1

1

High-throughput

0.437

High

428677

TRY1
Serine protease 1

1

4

High-throughput

0.437

High

440476

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.437

High

478707

PRS56
Serine protease 56

1

1

High-throughput

0.437

High

564490

RHOQ
Rho-related GTP-binding protein RhoQ

1

2

High-throughput

0.437

High

569628

CEBPB
CCAAT/enhancer-binding protein beta

1

7

High-throughput

0.437

High

596000

EFNA1
Ephrin-A1

1

20

High-throughput

0.437

High

609818

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

14

High-throughput

0.437

High

627241

MCM3
DNA replication licensing factor MCM3

1

4

High-throughput

0.437

High

643482

PTBP1
Polypyrimidine tract-binding protein 1

1

1

High-throughput

0.437

High

719703

RADI
Radixin

1

2

High-throughput

0.437

High

856367

EFNA4
Ephrin-A4

1

20

High-throughput

0.437

High

903153

WDR5
WD repeat-containing protein 5

1

5

High-throughput

0.437

High

903896

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

3

High-throughput

0.437

High

917149

H4
Histone H4

1

1

High-throughput

0.437

High

980246

CNTN1
Contactin-1

1

1

High-throughput

0.437

High

980247

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.437

High

980249

DDX10
Probable ATP-dependent RNA helicase DDX10

1

8

High-throughput

0.437

High

980250

SRSF6
Serine/arginine-rich splicing factor 6

1

1

High-throughput

0.437

High

980251

DX39B
Spliceosome RNA helicase DDX39B

1

20

High-throughput

0.437

High

980255

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.437

High

980263

EZH2
Histone-lysine N-methyltransferase EZH2

1

14

High-throughput

0.437

High

980268

EMC4
ER membrane protein complex subunit 4

1

4

High-throughput

0.437

High

980270

ATD3C
ATPase family AAA domain-containing protein 3C

1

6

High-throughput

0.437

High

980279

MEPCE
7SK snRNA methylphosphate capping enzyme

1

14

High-throughput

0.437

High

980288

ARL10
ADP-ribosylation factor-like protein 10

1

10

High-throughput

0.437

High

980294

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

20

High-throughput

0.437

High

980295

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

2

Small-scale

0.437

High

980297

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

8

High-throughput

0.437

High

980300

HDAC2
Histone deacetylase 2

1

14

High-throughput

0.437

High

980301

ATOH1
Transcription factor ATOH1

1

2

High-throughput

0.437

High

980303

FGF11
Fibroblast growth factor 11

1

2

High-throughput

0.437

High

980304

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

3

High-throughput

0.437

High

980309

MBD6
Methyl-CpG-binding domain protein 6

1

5

High-throughput

0.437

High

980310

FUBP3
Far upstream element-binding protein 3

1

3

High-throughput

0.437

High

980311

H2A1H
Histone H2A type 1-H

1

1

High-throughput

0.437

High

980312

CCNL2
Cyclin-L2

1

8

High-throughput

0.437

High

980315

TBB2B
Tubulin beta-2B chain

1

1

High-throughput

0.437

High

980317

ACE2
Angiotensin-converting enzyme 2

1

7

High-throughput

0.437

High

980318

DDX24
ATP-dependent RNA helicase DDX24

1

20

High-throughput

0.437

High

980319

RNF38
E3 ubiquitin-protein ligase RNF38

1

3

Small-scale

0.437

High

980323

RC3H2
Roquin-2

1

19

High-throughput

0.437

High

980326

SAR1A
Small COPII coat GTPase SAR1A

1

10

High-throughput

0.437

High

980331

MBD5
Methyl-CpG-binding domain protein 5

1

3

High-throughput

0.437

High

980289

POC5
Centrosomal protein POC5

1

0

Small-scale

0.426

High

980252

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

High-throughput

0.407

High

980287

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.407

High

216999

TLL1
Tolloid-like protein 1

1

0

High-throughput

0.249

Low

262796

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.249

Low

388025

AMYP
Pancreatic alpha-amylase

1

0

High-throughput

0.249

Low

393171

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.249

Low

441111

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.249

Low

469811

FREM3
FRAS1-related extracellular matrix protein 3

1

0

High-throughput

0.249

Low

489730

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.249

Low

518981

PIP
Prolactin-inducible protein

1

0

High-throughput

0.249

Low

636897

ATPA
ATP synthase subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

852884

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

High-throughput

0.249

Low

885002

RGS8
Regulator of G-protein signaling 8

1

0

High-throughput

0.249

Low

901566

LYSC
Lysozyme C

1

0

High-throughput

0.249

Low

946501

DCD
Dermcidin

1

0

High-throughput

0.249

Low

950769

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.249

Low

980266

BRDT
Bromodomain testis-specific protein

1

0

High-throughput

0.249

Low

980273

IF5AL
Eukaryotic translation initiation factor 5A-1-like

1

0

High-throughput

0.249

Low

980291

DBF4B
Protein DBF4 homolog B

1

0

High-throughput

0.249

Low

980296

POF1B
Protein POF1B

1

0

High-throughput

0.249

Low

980306

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

Small-scale

0.249

Low

980332

CLCF1
Cardiotrophin-like cytokine factor 1

1

0

High-throughput

0.249

Low

980337

S4A4
Electrogenic sodium bicarbonate cotransporter 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024