Protein: RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerases I and III 16 kDa polypeptide) (RPA19)

Gene: RPAC2, RPC19
Organism: Saccharomyces cerevisiae S288C
Interactions: 128
UniProt ID: P28000

Gene Ontology (top 5):
GO:0001054 - RNA polymerase I activity
GO:0001056 - RNA polymerase III activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

429651

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

11

17

Small-scale

0.980

High

606563

RPC2
DNA-directed RNA polymerase III subunit RPC2

8

9

Small-scale

0.966

High

604511

RPA2
DNA-directed RNA polymerase I subunit RPA135

6

9

Small-scale

0.949

High

375585

RPC1
DNA-directed RNA polymerase III subunit RPC1

5

11

Small-scale

0.922

High

501329

RPA1
DNA-directed RNA polymerase I subunit RPA190

5

11

Small-scale

0.919

High

557923

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

17

Small-scale

0.775

High

593113

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

4

3

Small-scale

0.684

High

655595

RPA12
DNA-directed RNA polymerase I subunit RPA12

3

9

High-throughput

0.662

High

655601

RPC8
DNA-directed RNA polymerase III subunit RPC8

3

5

High-throughput

0.657

High

655591

RPC3
DNA-directed RNA polymerase III subunit RPC3

3

1

High-throughput

0.650

High

655623

RPA43
DNA-directed RNA polymerase I subunit RPA43

3

1

Small-scale

0.650

High

631646

RPC4
DNA-directed RNA polymerase III subunit RPC4

3

0

High-throughput

0.634

High

655625

RPA34
DNA-directed RNA polymerase I subunit RPA34

3

0

High-throughput

0.622

High

593289

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

3

High-throughput

0.618

High

655643

RAGAB
GTP-binding protein GTR1

2

0

Small-scale

0.613

High

593211

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

2

4

High-throughput

0.601

High

604657

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

4

High-throughput

0.601

High

655598

RPC6
DNA-directed RNA polymerase III subunit RPC6

2

1

High-throughput

0.601

High

655645

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

2

High-throughput

0.601

High

655588

TF3B
Transcription factor IIIB 70 kDa subunit

2

5

High-throughput

0.584

High

571998

RPC7
DNA-directed RNA polymerase III subunit RPC7

2

0

High-throughput

0.576

High

655630

RPC9
DNA-directed RNA polymerase III subunit RPC9

2

0

High-throughput

0.576

High

412527

CDC7
Cell division control protein 7

1

2

High-throughput

0.536

High

416199

SIR2
NAD-dependent histone deacetylase SIR2

1

1

High-throughput

0.515

High

615123

BUR1
Serine/threonine-protein kinase BUR1

1

1

High-throughput

0.515

High

356294

H4
Histone H4

1

0

High-throughput

0.513

High

655589

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

655612

RIX1
Pre-rRNA-processing protein RIX1

1

0

High-throughput

0.513

High

655646

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

655654

PDR8
Transcription factor PDR8

1

1

High-throughput

0.508

High

655594

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.493

High

655661

NSI1
RNA polymerase I termination factor

1

0

High-throughput

0.493

High

655634

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

1

High-throughput

0.489

High

655635

LIF1
Ligase-interacting factor 1

1

0

High-throughput

0.486

High

521116

RAD50
DNA repair protein RAD50

1

1

High-throughput

0.481

High

655626

YJ41B
Transposon Ty4-J Gag-Pol polyprotein

1

1

High-throughput

0.481

High

655649

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.481

High

412445

KIN28
Serine/threonine-protein kinase KIN28

1

0

High-throughput

0.480

High

630979

KCC4
Probable serine/threonine-protein kinase KCC4

1

0

High-throughput

0.480

High

655628

IKS1
Probable serine/threonine-protein kinase IKS1

1

0

High-throughput

0.480

High

454215

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.479

High

406845

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

655587

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.479

High

655596

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

2

High-throughput

0.479

High

655605

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

2

High-throughput

0.479

High

655617

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

3

High-throughput

0.479

High

655620

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.479

High

655624

TFC5
Transcription factor TFIIIB component B''

1

1

High-throughput

0.479

High

655642

SEN1
Helicase SEN1

1

2

High-throughput

0.479

High

655644

CDC14
Tyrosine-protein phosphatase CDC14

1

1

High-throughput

0.479

High

655650

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

655651

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

9

High-throughput

0.479

High

655655

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

655657

IWR1
RNA polymerase II nuclear localization protein IWR1

1

1

High-throughput

0.479

High

655660

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

655590

XPO1
Exportin-1

1

0

High-throughput

0.460

High

141198

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

339484

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.458

High

413349

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

419456

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

479966

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

526957

TBP
TATA-box-binding protein

1

0

High-throughput

0.458

High

630168

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

631715

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

634516

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

638656

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.458

High

645298

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

655602

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

655607

RRN10
RNA polymerase I-specific transcription initiation factor RRN10

1

0

High-throughput

0.458

High

655618

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

655631

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

655633

RPA14
DNA-directed RNA polymerase I subunit RPA14

1

0

High-throughput

0.458

High

655638

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

0

High-throughput

0.458

High

655641

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

655652

RBS1
RNA-binding suppressor of PAS kinase protein 1

1

0

Small-scale

0.458

High

655658

SGO1
Shugoshin

1

0

High-throughput

0.458

High

618313

STE11
Serine/threonine-protein kinase STE11

1

1

High-throughput

0.457

High

341952

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.457

High

423784

ATPA
ATP synthase subunit alpha, mitochondrial

1

3

High-throughput

0.457

High

555860

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.457

High

490526

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

493362

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

655615

PFD2
Prefoldin subunit 2

1

1

High-throughput

0.439

High

655600

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

655608

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

655627

NET1
Nucleolar protein NET1

1

1

High-throughput

0.437

High

655639

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.437

High

655648

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.437

High

655656

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

510485

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

655604

RRN3
RNA polymerase I-specific transcription initiation factor RRN3

1

0

Small-scale

0.426

High

655610

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

477967

HSP77
Import motor subunit, mitochondrial

1

3

High-throughput

0.407

High

655614

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.407

High

655653

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

5

High-throughput

0.407

High

655622

MIC19
MICOS complex subunit MIC19

2

0

High-throughput

0.326

High

655609

PHS
Putative pterin-4-alpha-carbinolamine dehydratase

2

0

High-throughput

0.314

High

655593

MDHP
Malate dehydrogenase, peroxisomal

1

0

High-throughput

0.269

Low

655599

BUD2
Inhibitory regulator protein BUD2/CLA2

1

0

High-throughput

0.269

Low

655662

ATG11
Autophagy-related protein 11

1

0

High-throughput

0.269

Low

360773

TBB
Tubulin beta chain

1

0

High-throughput

0.261

Low

367807

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.261

Low

389242

HXKA
Hexokinase-1

1

0

High-throughput

0.261

Low

452968

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

520794

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.261

Low

655619

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.261

Low

655592

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

655616

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

655629

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

655636

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

1

0

High-throughput

0.251

Low

655637

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

357928

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

405477

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

407774

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

425811

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

470906

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

480528

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

482124

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

655597

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

655603

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

655606

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

655611

NMD2
Nonsense-mediated mRNA decay protein 2

1

0

Small-scale

0.249

Low

655613

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

655621

BUD27
Bud site selection protein 27

1

0

High-throughput

0.249

Low

655632

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

655647

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

655659

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

655640

JJJ1
J protein JJJ1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024