Protein: ANT3
Antithrombin-III (ATIII) (Serpin C1)

Gene: ANT3, SERPINC1
Organism: Homo sapiens
Interactions: 52
UniProt ID: P01008

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

344110

FCGRN
IgG receptor FcRn large subunit p51

2

3

High-throughput

0.811

High

344093

ANT3
Antithrombin-III

2

6

Small-scale

0.799

High

341117

THRB
Prothrombin

2

20

Small-scale

0.768

High

344115

OS9
Protein OS-9

3

3

High-throughput

0.667

High

344129

TBB1
Tubulin beta-1 chain

3

1

High-throughput

0.667

High

344100

GRAA
Granzyme A

1

20

Small-scale

0.665

High

341268

FA9
Coagulation factor IX

1

20

Small-scale

0.647

High

341301

FA10
Coagulation factor X

1

20

Small-scale

0.647

High

344097

KLK1
Kallikrein-1

1

20

Small-scale

0.647

High

344107

BTD
Biotinidase

3

0

High-throughput

0.638

High

344096

IC1
Plasma protease C1 inhibitor

1

8

High-throughput

0.618

High

344118

TBB8
Tubulin beta-8 chain

2

1

High-throughput

0.611

High

344130

DDX31
ATP-dependent DNA helicase DDX31

2

5

High-throughput

0.574

High

344099

BIP
Endoplasmic reticulum chaperone BiP

1

10

High-throughput

0.536

High

344101

CFTR
Cystic fibrosis transmembrane conductance regulator

1

9

High-throughput

0.536

High

344132

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

3

High-throughput

0.536

High

344135

HYOU1
Hypoxia up-regulated protein 1

1

6

High-throughput

0.536

High

344105

MCH
Pro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid

1

0

High-throughput

0.513

High

344098

HS90A
Heat shock protein HSP 90-alpha

1

6

Small-scale

0.501

High

208025

HAIR
Lysine-specific demethylase hairless

1

1

High-throughput

0.489

High

344113

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

9

High-throughput

0.489

High

344119

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

6

High-throughput

0.489

High

344124

HBAP1
HSPB1-associated protein 1

1

4

High-throughput

0.489

High

344125

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

2

High-throughput

0.489

High

344114

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

2

Small-scale

0.484

High

344122

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

Small-scale

0.480

High

344104

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

1

High-throughput

0.479

High

344094

CO3
Complement C3

1

0

High-throughput

0.458

High

344095

HRG
Histidine-rich glycoprotein

1

0

High-throughput

0.458

High

226207

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.437

High

260422

PITX3
Pituitary homeobox 3

1

4

Small-scale

0.437

High

344102

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

344103

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.437

High

344106

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

344108

SOX2
Transcription factor SOX-2

1

13

High-throughput

0.437

High

344111

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.437

High

344116

CUL2
Cullin-2

1

6

Small-scale

0.437

High

344121

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

4

Small-scale

0.437

High

344127

FACD2
Fanconi anemia group D2 protein

1

12

High-throughput

0.437

High

344128

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

4

High-throughput

0.437

High

344131

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.437

High

344134

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

4

Small-scale

0.437

High

344123

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.407

High

344109

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

3

0

High-throughput

0.347

High

344126

TEX15
Testis-expressed protein 15

3

0

High-throughput

0.347

High

344117

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.279

Low

344133

ING4
Inhibitor of growth protein 4

1

0

High-throughput

0.279

Low

233135

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

271011

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

0

Small-scale

0.249

Low

344112

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.249

Low

344120

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024