HitPredict

Interactor 1: PRDX3 (P20108)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (PRX III) (Perioredoxin-3) (Protein MER5) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Interactor 2: THIOM (P97493)
Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)
Gene: Txn2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	31018154
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	1-cysPrx_C~Thioredoxin, AhpC-TSA~Thioredoxin
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 257 Mm			1 166
+	Mm
		1021693 PRDX2_MOUSE (60-256): 9.26e-105: 303: 62.94		THIOM_MOUSE (1-166): 5.65e-54: 170: 100.00
+	Mm
		148340 PRDX4_MOUSE (40-256): 2.39e-101: 297: 58.53		THIOM_MOUSE (1-166): 5.65e-54: 170: 100.00
+	Mm
		776005 PRDX1_MOUSE (60-254): 1.56e-100: 293: 61.74		THIOM_MOUSE (1-166): 5.65e-54: 170: 100.00
+	Hs
		566569 PRDX3_HUMAN (1-257): 6.54e-119: 341: 85.60		PDIA4_HUMAN (60-165): 1.13e-28: 112: 27.52
+	Hs
		528200 PRDX2_HUMAN (60-256): 1.29e-104: 303: 63.45		THIO_HUMAN (61-165): 5.2e-37: 124: 34.91
+	Hs
		452246 PRDX4_HUMAN (40-256): 8.46e-101: 296: 58.07		PDIA1_HUMAN (52-166): 9.36e-35: 128: 27.50
+	Os
		1232160 BAS1_ORYSJ (1-255): 3.38e-102: 299: 45.98		TRXX_ORYSJ (1-165): 4.57e-36: 124: 22.99
+	Hs
		1096965 PRDX4_HUMAN (40-256): 8.46e-101: 296: 58.07		PDIA6_HUMAN (62-165): 1.24e-32: 122: 23.81
+	Hs
		528237 PRDX1_HUMAN (60-254): 1.03e-100: 293: 63.27		THIO_HUMAN (61-165): 5.2e-37: 124: 34.91
+	At
		1319812 BAS1B_ARATH (17-255): 1.39e-98: 290: 47.11		TRXX_ARATH (5-165): 7.3e-36: 124: 22.75
+	Hs
		717461 PRDX4_HUMAN (40-256): 8.46e-101: 296: 58.07		PDIA3_HUMAN (49-163): 3.44e-30: 115: 23.53
+	So
		200683 BAS1_SPIOL (1-255): 5.69e-94: 278: 43.45		TRXM_SPIOL (52-165): 6.34e-39: 132: 28.95
+	Hs
		566655 PRDX4_HUMAN (40-256): 8.46e-101: 296: 58.07		PDIA4_HUMAN (60-165): 1.13e-28: 112: 27.52
+	Rn
		801674 PRDX4_RAT (40-256): 3.62e-101: 297: 58.07		PDIA4_RAT (16-165): 2.11e-28: 111: 23.23
+	Dm
		1464120 Q9V3Q4_DROME (40-256): 4.55e-95: 280: 56.68		THIO2_DROME (61-162): 5.97e-37: 124: 37.86
+	At
		1319811 BAS1A_ARATH (58-255): 1.7e-93: 277: 54.00		TRXX_ARATH (5-165): 7.3e-36: 124: 22.75
+	Ss
		910416 Y755_SYNY3 (61-257): 1.11e-91: 270: 54.55		THIO_SYNY3 (59-165): 4.91e-39: 130: 31.78
+	Sc
		652865 TSA1_YEAST (62-257): 5.37e-90: 266: 58.16		TRX2_YEAST (61-154): 2.22e-36: 123: 31.92
+	Sc
		646595 TSA1_YEAST (62-257): 5.37e-90: 266: 58.16		TRX1_YEAST (61-154): 6.49e-36: 122: 37.23
+	Ss
		910432 Y755_SYNY3 (61-257): 1.11e-91: 270: 54.55		THIO1_SYNY3 (65-151): 2.31e-34: 118: 31.03