Protein: RFC2
Replication factor C subunit 2 (Replication factor C2) (Activator 1 41 kDa subunit)

Gene: RFC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 112
UniProt ID: P40348

Gene Ontology (top 5):
GO:0000076 - DNA replication checkpoint signaling
GO:0000077 - DNA damage checkpoint signaling
GO:0003677 - DNA binding
GO:0003689 - DNA clamp loader activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

751269

RFC3
Replication factor C subunit 3

12

15

Small-scale

0.980

High

747110

RFC5
Replication factor C subunit 5

9

16

Small-scale

0.968

High

772247

RFC4
Replication factor C subunit 4

8

15

Small-scale

0.960

High

751312

RFC1
Replication factor C subunit 1

7

20

Small-scale

0.949

High

550554

PCNA
Proliferating cell nuclear antigen

5

16

Small-scale

0.924

High

772422

CTF18
Chromosome transmission fidelity protein 18

5

17

Small-scale

0.916

High

697297

RAD24
Checkpoint protein RAD24

8

20

Small-scale

0.752

High

772442

ELG1
Telomere length regulation protein ELG1

8

17

Small-scale

0.748

High

756643

CTF8
Chromosome transmission fidelity protein 8

2

3

Small-scale

0.621

High

772281

ATAD2
ATPase histone chaperone YTA7

1

5

High-throughput

0.618

High

772435

RUVB1
RuvB-like protein 1

1

11

High-throughput

0.618

High

772446

RUVB2
RuvB-like protein 2

1

11

High-throughput

0.618

High

356514

H4
Histone H4

2

7

High-throughput

0.584

High

392455

H2A2
Histone H2A.2

2

7

High-throughput

0.584

High

772420

TCPQ
T-complex protein 1 subunit theta

2

2

High-throughput

0.584

High

494123

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.552

High

768579

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

372826

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

2

High-throughput

0.536

High

423464

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

1

High-throughput

0.536

High

676108

XPO1
Exportin-1

1

9

High-throughput

0.536

High

697219

BRR2
Pre-mRNA-splicing helicase BRR2

1

4

High-throughput

0.536

High

700451

RSSA1
Small ribosomal subunit protein uS2A

2

4

High-throughput

0.521

High

706309

RS3A1
Small ribosomal subunit protein eS1A

2

3

High-throughput

0.521

High

772415

ECO1
N-acetyltransferase ECO1

1

3

Small-scale

0.515

High

679835

NTH1
Endonuclease III homolog 1

1

0

High-throughput

0.513

High

772424

ROM2
RHO1 GDP-GTP exchange protein 2

1

0

High-throughput

0.513

High

772429

EF3B
Elongation factor 3B

1

0

High-throughput

0.513

High

772434

IMA1
Importin subunit alpha

1

0

High-throughput

0.513

High

745688

NU170
Nucleoporin NUP170

1

3

High-throughput

0.504

High

747175

MMS4
Crossover junction endonuclease MMS4

1

1

Small-scale

0.501

High

772436

MUS81
Crossover junction endonuclease MUS81

1

1

Small-scale

0.501

High

342035

ATPB
ATP synthase subunit beta, mitochondrial

1

7

High-throughput

0.500

High

498529

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.500

High

583231

METK2
S-adenosylmethionine synthase 2

1

1

High-throughput

0.500

High

633273

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.500

High

664866

BMH1
Protein BMH1

1

1

High-throughput

0.500

High

767651

IMB4
Importin subunit beta-4

1

2

High-throughput

0.500

High

765785

VAC8
Vacuolar protein 8

1

1

High-throughput

0.489

High

772416

RSSA2
Small ribosomal subunit protein uS2B

1

4

High-throughput

0.489

High

772423

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.489

High

772419

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.486

High

772447

CMR1
DNA damage-binding protein CMR1

1

5

High-throughput

0.481

High

355505

H2B1
Histone H2B.1

1

14

High-throughput

0.479

High

355909

H2B2
Histone H2B.2

1

14

High-throughput

0.479

High

389646

DNLI1
DNA ligase 1

1

3

Small-scale

0.479

High

407092

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

420134

TOP2
DNA topoisomerase 2

1

1

High-throughput

0.479

High

543852

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.479

High

558090

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.479

High

634057

DCC1
Sister chromatid cohesion protein DCC1

1

7

High-throughput

0.479

High

662396

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

688271

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.479

High

689888

ASF1
Histone chaperone ASF1

1

3

Small-scale

0.479

High

698830

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

3

High-throughput

0.479

High

772414

DSN1
Kinetochore-associated protein DSN1

1

3

High-throughput

0.479

High

772427

HST2
NAD-dependent protein deacetylase HST2

1

2

High-throughput

0.479

High

772431

H3
Histone H3

1

13

High-throughput

0.479

High

772432

CTF4
DNA polymerase alpha-binding protein

1

5

Small-scale

0.479

High

772440

SGO1
Shugoshin

1

3

High-throughput

0.479

High

772443

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

2

High-throughput

0.479

High

772444

SCC1
Sister chromatid cohesion protein 1

1

4

High-throughput

0.479

High

772437

IVY1
Protein IVY1

1

1

High-throughput

0.464

High

772438

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

397599

OTC
Ornithine carbamoyltransferase

1

2

High-throughput

0.457

High

772430

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

2

High-throughput

0.457

High

366387

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.445

High

478250

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.445

High

491410

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

511537

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

694816

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

728143

MPE1
Protein MPE1

1

0

High-throughput

0.438

High

141369

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.437

High

358099

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

383184

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.437

High

405660

RL26A
Large ribosomal subunit protein uL24A

1

6

High-throughput

0.437

High

407953

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.437

High

413542

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.437

High

425989

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.437

High

471091

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

472227

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

480139

RS6A
Small ribosomal subunit protein eS6A

1

5

High-throughput

0.437

High

480705

RS8A
Small ribosomal subunit protein eS8A

1

5

High-throughput

0.437

High

482293

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.437

High

631917

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.437

High

645481

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.437

High

701461

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

729947

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.437

High

752490

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.437

High

755089

NMD2
Nonsense-mediated mRNA decay protein 2

1

1

Small-scale

0.437

High

762261

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

772421

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.437

High

772425

RL26B
Large ribosomal subunit protein uL24B

1

6

High-throughput

0.437

High

772428

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.437

High

772433

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.437

High

772439

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.437

High

772441

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

404607

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.407

High

405206

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.407

High

613707

RS3A2
Small ribosomal subunit protein eS1B

1

3

High-throughput

0.407

High

667196

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.407

High

772417

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.407

High

772445

RL7B
Large ribosomal subunit protein uL30B

1

2

High-throughput

0.407

High

604267

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.279

Low

687063

ACH1
Acetyl-CoA hydrolase

1

0

High-throughput

0.279

Low

739488

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.279

Low

743810

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

549674

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.261

Low

772413

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.261

Low

524333

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

732147

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.238

Low

772418

MRX5
MIOREX complex component 5

1

0

High-throughput

0.238

Low

772426

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024