Protein: UME1
Transcriptional regulatory protein UME1 (WD repeat-containing transcriptional modulator 3)

Gene: UME1
Organism: Saccharomyces cerevisiae S288C
Interactions: 76
UniProt ID: Q03010

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006334 - nucleosome assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

693057

RPD3
Histone deacetylase RPD3

14

0

Small-scale

0.728

High

609135

SIN3
Transcriptional regulatory protein SIN3

12

0

Small-scale

0.723

High

974210

RCO1
Transcriptional regulatory protein RCO1

9

0

Small-scale

0.720

High

974218

CTI6
Histone deacetylase complex subunit CTI6

7

0

Small-scale

0.711

High

747159

RXT2
Transcriptional regulatory protein RXT2

7

0

Small-scale

0.709

High

680088

DEP1
Transcriptional regulatory protein DEP1

5

0

Small-scale

0.682

High

974220

EAF3
Chromatin modification-related protein EAF3

5

0

Small-scale

0.682

High

750111

SAP30
Transcriptional regulatory protein SAP30

4

0

Small-scale

0.661

High

974212

RXT3
Transcriptional regulatory protein RXT3

3

0

High-throughput

0.634

High

842778

PHO23
Transcriptional regulatory protein PHO23

3

0

Small-scale

0.628

High

902020

H3
Histone H3

3

0

Small-scale

0.619

High

710739

ASH1
Transcriptional regulatory protein ASH1

3

0

Small-scale

0.606

High

774793

SDS3
Transcriptional regulatory protein SDS3

2

0

High-throughput

0.585

High

705567

HSP78
Heat shock protein 78, mitochondrial

2

2

High-throughput

0.571

High

769274

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.552

High

774565

XBP1
Transcriptional repressor XBP1

2

0

Small-scale

0.547

High

972883

IMA1
Importin subunit alpha

1

1

High-throughput

0.536

High

974214

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.518

High

634262

GID7
Glucose-induced degradation protein 7

1

0

High-throughput

0.513

High

974205

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.513

High

565748

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

648235

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.480

High

765368

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

High-throughput

0.480

High

798330

TOS3
Serine/threonine-protein kinase TOS3

1

0

High-throughput

0.480

High

974206

SKY1
Serine/threonine-protein kinase SKY1

1

0

High-throughput

0.480

High

974216

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.480

High

342766

ENO1
Enolase 1

1

0

High-throughput

0.479

High

663113

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

701060

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

974204

UME1
Transcriptional regulatory protein UME1

1

3

Small-scale

0.479

High

974207

RUVB1
RuvB-like protein 1

1

4

High-throughput

0.479

High

974211

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

974213

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

974219

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

974223

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.479

High

141494

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

356677

H4
Histone H4

1

0

High-throughput

0.458

High

407271

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

408087

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

482425

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

632054

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

637157

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

0

High-throughput

0.458

High

655676

FUN19
SWIRM domain-containing protein FUN19

1

0

High-throughput

0.458

High

687736

BTAF1
TATA-binding protein-associated factor MOT1

1

0

Small-scale

0.458

High

692890

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.458

High

694205

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

716334

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

742963

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

752633

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

758976

UME6
Transcriptional regulatory protein UME6

1

0

Small-scale

0.458

High

967721

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

974208

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

974215

SGO1
Shugoshin

1

0

High-throughput

0.458

High

974222

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

492216

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

494784

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

512460

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

695372

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

797070

RGD2
Rho-GTPase-activating protein RGD2

1

0

High-throughput

0.438

High

355604

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

974209

DHR1
Probable ATP-dependent RNA helicase DHR1

2

0

High-throughput

0.324

High

520358

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

0

High-throughput

0.282

High

974221

OSH2
Oxysterol-binding protein homolog 2

1

0

High-throughput

0.282

High

378388

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

358228

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

383321

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

405799

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

413677

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

426121

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

471221

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

480846

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

645618

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

706454

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

852228

YPT32
GTP-binding protein YPT32/YPT11

1

0

High-throughput

0.249

Low

974217

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024