Protein: MK08
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)

Gene: MK08, Mapk8
Organism: Mus musculus
Interactions: 32
UniProt ID: Q91Y86

Gene Ontology (top 5):
GO:0001503 - ossification
GO:0001764 - neuron migration
GO:0002102 - podosome
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

432100

JUN
Transcription factor Jun

11

20

Small-scale

0.755

High

1353898

ZBT7C
Zinc finger and BTB domain-containing protein 7C

1

4

Small-scale

0.724

High

1362367

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

4

20

Small-scale

0.692

High

382506

P53
Cellular tumor antigen p53

4

12

Small-scale

0.676

High

107144

F8VQ72
Mitogen-activated protein kinase kinase kinase 1

1

20

Small-scale

0.618

High

723504

SSR3
Somatostatin receptor type 3

1

5

High-throughput

0.618

High

772576

IRS1
Insulin receptor substrate 1

1

8

Small-scale

0.618

High

1362368

DUS10
Dual specificity protein phosphatase 10

1

20

Small-scale

0.618

High

570732

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

4

Small-scale

0.586

High

1362370

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

2

9

Small-scale

0.584

High

591066

KPCE
Protein kinase C epsilon type

1

13

Small-scale

0.575

High

988908

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

Small-scale

0.575

High

1201712

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

20

Small-scale

0.561

High

205210

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.529

High

1021077

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog

1

13

Small-scale

0.501

High

236687

B2L11
Bcl-2-like protein 11

1

3

Small-scale

0.479

High

312233

KLC1
Kinesin light chain 1

1

3

Small-scale

0.479

High

665162

GSTA4
Glutathione S-transferase A4

1

8

Small-scale

0.479

High

1059025

NFE2
Transcription factor NF-E2 45 kDa subunit

1

13

Small-scale

0.479

High

1237814

MABP1
Mitogen-activated protein kinase-binding protein 1

1

15

Small-scale

0.479

High

1243983

SARM1
NAD(+) hydrolase SARM1

1

5

Small-scale

0.479

High

1362284

WWOX
WW domain-containing oxidoreductase

1

3

Small-scale

0.479

High

1362365

APBB2
Amyloid beta precursor protein binding family B member 2

1

2

Small-scale

0.479

High

1362366

ASC
Apoptosis-associated speck-like protein containing a CARD

1

1

Small-scale

0.479

High

1362369

P73
Tumor protein p73

1

12

Small-scale

0.479

High

1362371

BCL10
B-cell lymphoma/leukemia 10

1

1

Small-scale

0.479

High

866492

PA24A
Cytosolic phospholipase A2

1

7

High-throughput

0.457

High

1036083

CTNB1
Catenin beta-1

1

11

Small-scale

0.445

High

73133

B1AXJ3
Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

1

1

Small-scale

0.437

High

693167

TNR5
Tumor necrosis factor receptor superfamily member 5

1

7

Small-scale

0.437

High

1296671

JKAMP
JNK1/MAPK8-associated membrane protein

1

1

Small-scale

0.437

High

599657

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

20

Small-scale

0.338

High


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Last updated: 11Aug2025