Protein: PSA3
Proteasome subunit alpha type-3 (Macropain subunit Y13) (Multicatalytic endopeptidase complex subunit Y13) (Proteasome component Y13) (Proteinase YSCE subunit 13)

Gene: PSA3, PRE9
Organism: Saccharomyces cerevisiae S288C
Interactions: 97
UniProt ID: P23638

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019773 - proteasome core complex, alpha-subunit complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604751

PSB4
Proteasome subunit beta type-4

14

20

Small-scale

0.981

High

619323

PSA2
Proteasome subunit alpha type-2

9

19

Small-scale

0.975

High

597201

PSA7
Probable proteasome subunit alpha type-7

7

19

Small-scale

0.963

High

619335

PSB5
Proteasome subunit beta type-5

7

20

Small-scale

0.958

High

597285

PSA1
Proteasome subunit alpha type-1

5

20

Small-scale

0.922

High

619364

PSA4
Proteasome subunit alpha type-4

5

19

Small-scale

0.922

High

619363

PSA6
Proteasome subunit alpha type-6

4

19

Small-scale

0.884

High

619325

PSB2
Proteasome subunit beta type-2

4

20

Small-scale

0.881

High

619354

UMP1
Proteasome maturation factor UMP1

4

0

Small-scale

0.836

High

619324

PSB6
Proteasome subunit beta type-6

2

20

High-throughput

0.776

High

619328

PSB3
Proteasome subunit beta type-3

2

20

High-throughput

0.776

High

619336

PSB7
Proteasome subunit beta type-7

2

20

High-throughput

0.776

High

619338

PSA5
Proteasome subunit alpha type-5

2

20

High-throughput

0.776

High

619355

PSB1
Proteasome subunit beta type-1

2

20

High-throughput

0.776

High

619345

PRS6A
26S proteasome regulatory subunit 6A

2

20

High-throughput

0.754

High

619382

PRS8
26S proteasome regulatory subunit 8 homolog

2

20

Small-scale

0.754

High

619370

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

10

20

Small-scale

0.751

High

619369

BLM10
Proteasome activator BLM10

2

8

Small-scale

0.727

High

619393

RPN8
26S proteasome regulatory subunit RPN8

4

16

Small-scale

0.691

High

619358

RPN10
26S proteasome regulatory subunit RPN10

3

12

High-throughput

0.662

High

477138

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

3

20

Small-scale

0.646

High

619397

POC4
Proteasome chaperone 4

1

0

Small-scale

0.631

High

619346

PRS6B
26S proteasome regulatory subunit 6B homolog

1

20

High-throughput

0.618

High

619347

PRS7
26S proteasome regulatory subunit 7 homolog

1

20

High-throughput

0.618

High

619365

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

High-throughput

0.618

High

619375

PRS10
26S proteasome subunit RPT4

1

20

High-throughput

0.618

High

619400

RPN6
26S proteasome regulatory subunit RPN6

1

20

High-throughput

0.618

High

619339

RPN12
26S proteasome regulatory subunit RPN12

2

3

Small-scale

0.586

High

619349

POC2
Proteasome assembly chaperone 2

1

0

High-throughput

0.586

High

619392

POC3
Proteasome chaperone 3

1

0

Small-scale

0.586

High

619356

ECM29
Proteasome component ECM29

2

9

High-throughput

0.584

High

619357

RPN1
26S proteasome regulatory subunit RPN1

2

20

Small-scale

0.584

High

619398

RPN5
26S proteasome regulatory subunit RPN5

2

20

Small-scale

0.584

High

619330

PWP2
Periodic tryptophan protein 2

2

3

High-throughput

0.567

High

619344

SUI1
Eukaryotic translation initiation factor eIF-1

2

4

Small-scale

0.555

High

619362

SSB2
Ribosome-associated molecular chaperone SSB2

2

10

High-throughput

0.552

High

619332

KCC1
Calcium/calmodulin-dependent protein kinase I

2

3

High-throughput

0.550

High

619388

POC1
Proteasome chaperone 1

1

0

High-throughput

0.517

High

619333

CIN8
Kinesin-like protein CIN8

1

5

High-throughput

0.515

High

619374

YG2A
Zinc finger protein YGR067C

1

19

High-throughput

0.515

High

412659

KAPA
cAMP-dependent protein kinase type 1

1

1

High-throughput

0.501

High

565460

PHO85
Cyclin-dependent protein kinase PHO85

1

7

High-throughput

0.501

High

619348

NOT4
General negative regulator of transcription subunit 4

1

2

High-throughput

0.501

High

619385

TDA1
Serine/threonine-protein kinase TDA1

1

6

High-throughput

0.501

High

618808

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

0

High-throughput

0.493

High

619342

PMD1
Negative regulator of sporulation PMD1

1

0

High-throughput

0.493

High

619352

CND2
Condensin complex subunit 2

1

0

High-throughput

0.493

High

619368

GNA1
Glucosamine 6-phosphate N-acetyltransferase

1

0

High-throughput

0.493

High

619396

PSF3
DNA replication complex GINS protein PSF3

1

0

High-throughput

0.493

High

392058

H2A1
Histone H2A.1

1

1

High-throughput

0.479

High

392306

H2A2
Histone H2A.2

1

1

High-throughput

0.479

High

543234

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

619326

SIS1
Protein SIS1

1

5

High-throughput

0.479

High

619327

BPH1
Beige protein homolog 1

1

10

High-throughput

0.479

High

619334

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

619340

RPN2
26S proteasome regulatory subunit RPN2

1

20

High-throughput

0.479

High

619341

RAD23
UV excision repair protein RAD23

1

20

High-throughput

0.479

High

619343

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

619361

RPN3
26S proteasome regulatory subunit RPN3

1

8

High-throughput

0.479

High

619371

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

11

High-throughput

0.479

High

619377

APJ1
J domain-containing protein APJ1

1

6

High-throughput

0.479

High

619378

H3
Histone H3

1

1

High-throughput

0.479

High

619380

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

5

Small-scale

0.479

High

619384

TOM1
E3 ubiquitin-protein ligase TOM1

1

10

High-throughput

0.479

High

619386

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

619387

RPN9
26S proteasome regulatory subunit RPN9

1

11

High-throughput

0.479

High

619390

RPN7
26S proteasome regulatory subunit RPN7

1

20

High-throughput

0.479

High

619401

CMR1
DNA damage-binding protein CMR1

1

3

High-throughput

0.479

High

619383

MLP1
Protein MLP1

1

3

High-throughput

0.470

High

619379

ACAC
Acetyl-CoA carboxylase

1

0

Small-scale

0.460

High

141826

RPN13
26S proteasome regulatory subunit RPN13

1

0

High-throughput

0.458

High

294094

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.458

High

406804

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

413318

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

470876

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

472028

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

619337

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

619381

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

619394

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

619351

AKL1
Serine/threonine-protein kinase AKL1

1

4

High-throughput

0.457

High

619372

TOS3
Serine/threonine-protein kinase TOS3

1

4

High-throughput

0.457

High

490393

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

619329

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.445

High

619376

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.445

High

619366

MLP2
Protein MLP2

1

4

High-throughput

0.437

High

619391

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

619395

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

608674

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.426

High

619399

HSP42
Heat shock protein 42

1

1

High-throughput

0.407

High

619331

FUB1
Silencing boundary-establishment protein FUB1

2

0

Small-scale

0.305

High

619350

YK50
Mitochondrial hydrolase YKR070W

1

0

High-throughput

0.269

Low

619367

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

0

High-throughput

0.269

Low

619373

PMT4
Dolichyl-phosphate-mannose--protein mannosyltransferase 4

1

0

High-throughput

0.269

Low

619353

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

619360

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.249

Low

619389

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.249

Low

619359

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024