Protein: GPNMB
Transmembrane glycoprotein NMB (Hematopoietic growth factor inducible neurokinin-1 type)

Gene: GPNMB
Organism: Homo sapiens
Interactions: 18
UniProt ID: Q14956

Gene Ontology (top 5):
GO:0001818 - negative regulation of cytokine production
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1133858

IL31R
Interleukin-31 receptor subunit alpha

2

1

High-throughput

0.628

High

363301

EGFR
Epidermal growth factor receptor

1

0

Small-scale

0.564

High

866686

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.536

High

1106539

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.486

High

420537

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

5

Small-scale

0.479

High

565621

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

5

Small-scale

0.479

High

1133860

ITSN2
Intersectin-2

1

0

High-throughput

0.460

High

157386

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

400848

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

537180

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

1113126

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1118404

PTK6
Protein-tyrosine kinase 6

1

0

Small-scale

0.458

High

1133861

FBXL4
F-box/LRR-repeat protein 4

2

0

High-throughput

0.328

High

623625

TFEB
Transcription factor EB

1

0

High-throughput

0.279

Low

1133859

NJMU
Protein Njmu-R1

1

0

High-throughput

0.279

Low

330973

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.249

Low

1133857

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low

1133856

KLH22
Kelch-like protein 22

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025